Evidence for soft selective sweeps in the evolution of pneumococcal multidrug resistance and vaccine escape

Genome Biology and Evolution

Volumn 6, Issue 7, 2014, Pages 1589-1602

  Croucher, Nicholas J ^a,b   Chewapreecha, Claire ^b   Hanage, William P ^a   Harris, Simon R ^b   McGee, Lesley ^c   Van Der Linden, Mark ^d   Song, Jae Hoon ^e   Ko, Kwan Soo ^f   De Lencastre, Herminia ^g,h   Turner, Claudia ^i,j   Yang, Fan ^k   Sa Leao, Raquel ^g   Beall, Bernard ^c   Klugman, Keith P ^l,m   Parkhill, Julian ^b   Turner, Paul ^i,j   Bentley, Stephen D ^b,n  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^e Samsung Medical Center   (South Korea)

^f Sungkyunkwan University   (South Korea)

^g INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^h ROCKEFELLER UNIVERSITY   (United States)

ⁱ MAHIDOL UNIVERSITY   (Thailand)

^j UNIVERSITY OF OXFORD   (United Kingdom)

^k FUDAN UNIVERSITY   (China)

^l EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

ⁿ UNIVERSITY OF CAMBRIDGE   (United Kingdom)

more..

Author keywords

Antibiotic resistance; Bacterial evolution; Phylogenomics; Recombination; Selective sweeps; Vaccine escape

Indexed keywords

PNEUMOCOCCUS VACCINE;

CHROMOSOME MAP; GENETIC RECOMBINATION; GENETIC SELECTION; GENETICS; HUMAN; IMMUNOLOGY; MOLECULAR EVOLUTION; MULTIDRUG RESISTANCE; PHYLOGENY; STREPTOCOCCUS PNEUMONIAE;

CHROMOSOME MAPPING; DRUG RESISTANCE, MULTIPLE; EVOLUTION, MOLECULAR; HUMANS; PHYLOGENY; PNEUMOCOCCAL VACCINES; RECOMBINATION, GENETIC; SELECTION, GENETIC; STREPTOCOCCUS PNEUMONIAE;

EID: 84923323708     PISSN: None     EISSN: 17596653     Source Type: Journal    
DOI: 10.1093/gbe/evu120     Document Type: Article

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