Mechanism of sulfonamide resistance in clinical isolates of Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 10, 1997, Pages 2121-2126

  Maskell, Jeffrey P ^a   Sefton, Armine M ^a   Hall, Lucinda M C ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROPTEROATE SYNTHASE; SULFONAMIDE;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; GENE DUPLICATION; GENETIC POLYMORPHISM; GENETIC TRANSFORMATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

EID: 0030793841     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.10.2121     Document Type: Article

References (23)

1. Barry, A. L., and C. Thornsberry. 1985. Susceptibility tests: diffusion test procedures, p. 978-990. In E. H. Lennette, A. Balows, W. J. Hausler, Jr., and H. J. Shadomy (ed.), Manual of clinical microbiology, 4th ed. American Society for Microbiology, Washington, D.C.
2. Brown, G. M. 1962. The biosynthesis of folic acid. II. Inhibition by sulfonamides. J. Biol. Chem. 237:536-540.
3. Carvalho, C., P. Geslin, and M. V. Vaz Pato. 1996. Pulsed field gel electrophoresis in Streptococcus pneumoniae isolated in France and Portugal. Pathol. Biol. 44:430-434.
4. Coffey, T. J., C. G. Dowson, M. Daniels, J. Zhou, C. Martin, B. G. Spratt, and J. M. Musser. 1991. Horizontal transfer of multiple penicillin-binding protein genes, and capsular biosynthetic genes, in natural populations of Streptococcus pneumoniae. Mol. Microbiol. 5:2255-2260.
5. Dowson, C. G., T. J. Coffey, C. Kell, and R. A. Whiley. 1993. Evolution of penicillin resistance in Streptococcus pneumoniae: the role of Streptococcus mitis in the formation of a low affinity PBP2B in S. pneumoniae. Mol. Microbiol. 9:635-643.
6. Dowson, C. G., A. Hutchison, J. A. Brannigan, R. C. George, D. Hansman, J. Linares, A. Tomasz, J. M. Smith, and B. G. Spratt. 1989. Horizontal transfer of penicillin binding protein genes in penicillin resistant clinical isolates of Streptococcus pneumoniae. Proc. Natl. Acad. Sci. USA 86:8842-8846.
7. Garnier, J., D. J. Osguthorpe, and B. Robson. 1978. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J. Mol. Biol. 120:97-120.
8. Gasc, A. M., P. Geslin, and A. M. Sicard. 1995. Relatedness of penicillin-resistant Streptococcus pneumoniae serotype 9 strains from France and Spain. Microbiology 141:623-627.
9. Hall, L. M. C., R. A. Whiley, B. Duke, R. C. George, and A. Efstratiou. 1996. Genetic relatedness within and between serotypes of Streptococcus pneumoniae from the United Kingdom: analysis of multilocus enzyme electrophoresis, pulsed-field gel electrophoresis, and antimicrobial resistance patterns. J. Clin. Microbiol. 34:853-859.
10. Huovinen, P., L. Sundstrom, G. Swedberg, and O. Sköld. 1995. Trimethoprim and sulfonamide resistance. Antimicrob. Agents Chemother. 39: 279-289.
11. Klugman, K. P. 1990. Pneumococcal resistance to antibiotics. Clin. Microbiol. Rev. 3:171-196.
12. Koornhof, H. J., A. Wasas, and K. Klugman. 1992. Antimicrobial resistance in Streptococcus pneumoniae: a South African perspective. Clin. Infect. Dis. 15:84-94.
13. Lefevre, J. C., M. A. Bertrand, and G. Faucon. 1995. Molecular analysis by pulsed-field gel electrophoresis of penicillin-resistant Streptococcus pneumoniae from Toulouse, France. Eur. J. Clin. Microbiol. Infect. Dis. 14:491-497.
14. Lopez, P., M. Espinosa, B. Greenberg, and S. A. Lacks. 1987. Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme. J. Bacteriol. 169:4320-4326.
15. Marton, A., M. Gulyas, R. Munoz, and A. Tomasz. 1991. Extremely high incidence of antibiotic resistance in clinical isolates of Streptococcus pneumoniae in Hungary. J. Infect. Dis. 163:542-548.
16. Morrison, D. A., S. A. Lacks, W. R. Guild, and J. M. Hageman. 1983. Isolation and characterization of three new classes of transformation-deficient mutants of Streptococcus pneumoniae that are defective in DNA transport and genetic recombination. J. Bacteriol. 156:281-290.
17. National Committee for Clinical Laboratory Standards. 1997. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. National Committee for Clinical Laboratory Standards Villanova, Pa.
18. Perez, J. L., J. Linares, J. Bosch, M. J. Lopez de Goicoechea, and R. Martin. 1987. Antibiotic resistance of Streptococcus pneumoniae in childhood carriers. J. Antimicrob. Chemother. 19:278-280.
19. Porter, R. D., and W. R. Guild. 1976. Characterization of some pneumococcal bacteriophages. J. Virol. 19:659-667.
20. Rådström, P., C. Fermér, B.-E. Kristiansen, A. Jenkins, O. Sköld, and G. Swedberg. 1992. Transformational exchanges in the dihydropteroate synthase gene of Neisseria meningitidis: a novel mechanism for acquisition of sulfonamide resistance. J. Bacteriol. 174:6386-6393.
21. Reichmann, P., E. Varon, E. Gunther, R. R. Reinert, R. Luttiken, A. Marton, P. Geslin, J. Wagner, and R. Hakenbeck. 1995. Penicillin-resistant Streptococcus pneumoniae in Germany: genetic relationship to clones from other European countries. J. Med. Microbiol. 43:377-385.
22. Sibold, C., J. Wang, J. Henrichsen, and R. Hakenbeck. 1992. Genetic relationships of penicillin-susceptible and -resistant Streptococcus pneumoniae strains isolated on different continents. Infect. Immun. 60:4119-4126.
23. Vaz Pato, M. V., C. Belo de Carvalho, A. Tomasz, and the Multicenter Study Group. 1995. Antibiotic susceptibility of Streptococcus pneumoniae isolates in Portugal. A multicenter study between 1989 and 1993. Microb. Drug Res. 1:59-69.