Selection of DNA-encoded small molecule libraries against unmodified and non-immobilized protein targets

Angewandte Chemie - International Edition

Volumn 53, Issue 38, 2014, Pages 10056-10059

  Zhao, Peng ^a   Chen, Zitian ^b   Li, Yizhou ^a   Sun, Dawei ^a   Gao, Yuan ^a   Huang, Yanyi ^b   Li, Xiaoyu ^a,b  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

DNA; DNA encoded library; DNA templated chemistry; drug discovery; selection

Indexed keywords

CROSSLINKING; LIBRARIES; PROTEINS;

BIOLOGICAL TARGETS; DRUG DISCOVERY; IMMOBILIZED PROTEINS; PHOTOCROSS-LINKING; PROTECTION STRATEGY; SELECTION; SMALL-MOLECULE LIBRARY; TEMPLATED;

DNA;

DNA; LIGAND; MOLECULAR LIBRARY; PROTEIN;

ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; SYNTHESIS;

DNA; LIGANDS; MOLECULAR STRUCTURE; PROTEINS; SMALL MOLECULE LIBRARIES;

EID: 84923301851     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201404830     Document Type: Article

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