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Volumn 10, Issue 2, 2015, Pages

High mobility group box 1 induced human lung myofibroblasts differentiation and enhanced migration by activation of MMP-9

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; GELATINASE B; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; ADVANCED GLYCATION END PRODUCT RECEPTOR; IMMUNOGLOBULIN RECEPTOR;

EID: 84923278196     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116393     Document Type: Article
Times cited : (45)

References (40)
  • 1
    • 4644241215 scopus 로고    scopus 로고
    • Differences in airway remodeling between asthma and chronic obstructive pulmonary disease
    • pmid:15347849
    • Aoshiba K, Nagai A (2004) Differences in airway remodeling between asthma and chronic obstructive pulmonary disease. Clin Rev Allergy Immunol 27:35-43. pmid:15347849 doi: 10.1385/criai:27:1:035
    • (2004) Clin Rev Allergy Immunol , vol.27 , pp. 35-43
    • Aoshiba, K.1    Nagai, A.2
  • 2
    • 24644520068 scopus 로고    scopus 로고
    • Airway remodeling contributes to the progressive loss of lung function in asthma: An overview
    • quiz 487, pmid:16159612
    • Pascual RM, Peters SP (2005) Airway remodeling contributes to the progressive loss of lung function in asthma: an overview. J Allergy Clin Immunol 116:477-486; quiz 487. pmid:16159612 doi: 10.1016/j.jaci.2005.07.011
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 477-486
    • Pascual, R.M.1    Peters, S.P.2
  • 3
    • 84876282871 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smoke
    • pmid:23299965
    • Milara J, Peiro T, Serrano A, Cortijo J (2013) Epithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smoke. Thorax 68:410-420. doi: 10.1136/thoraxjnl-2012-201761. pmid:23299965
    • (2013) Thorax , vol.68 , pp. 410-420
    • Milara, J.1    Peiro, T.2    Serrano, A.3    Cortijo, J.4
  • 4
    • 24944464002 scopus 로고    scopus 로고
    • Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease
    • pmid:16113432
    • Jeffery PK (2004) Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 1:176-183. pmid:16113432 doi: 10.1513/pats.200402-009ms
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 176-183
    • Jeffery, P.K.1
  • 5
    • 0028353880 scopus 로고
    • Hypothesis: Excessive bronchoconstriction in asthma is due to decreased airway elastance
    • pmid:8162988
    • Bramley AM, Thomson RJ, Roberts CR, Schellenberg RR (1994) Hypothesis: excessive bronchoconstriction in asthma is due to decreased airway elastance. Eur Respir J 7:337-341. pmid:8162988 doi: 10.1183/09031936.9407020337
    • (1994) Eur Respir J , vol.7 , pp. 337-341
    • Bramley, A.M.1    Thomson, R.J.2    Roberts, C.R.3    Schellenberg, R.R.4
  • 6
    • 14844337560 scopus 로고    scopus 로고
    • Airway fibroblasts exhibit a synthetic phenotype in severe asthma
    • pmid:15753901
    • Lewis CC, Chu HW, Westcott JY, Tucker A, Langmack EL, et al. (2005) Airway fibroblasts exhibit a synthetic phenotype in severe asthma. J Allergy Clin Immunol 115:534-540. pmid:15753901 doi: 10.1016/j.jaci.200411.051
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 534-540
    • Lewis, C.C.1    Chu, H.W.2    Westcott, J.Y.3    Tucker, A.4    Langmack, E.L.5
  • 7
    • 0015857760 scopus 로고
    • A new group of chromatin-associated proteins with a high content of acidic and basic amino acids
    • Goodwin GH, Sanders C, Johns EW (1973) A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem 38:14-19. doi: 10.1111/j.1432-1033.1973.tb03026.x
    • (1973) Eur J Biochem , vol.38 , pp. 14-19
    • Goodwin, G.H.1    Sanders, C.2    Johns, E.W.3
  • 8
    • 0034698830 scopus 로고    scopus 로고
    • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    • pmid:10952726
    • Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, et al. (2000) High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 192:565-570. pmid:10952726 doi: 10.1084/jem.192.4.565
    • (2000) J Exp Med , vol.192 , pp. 565-570
    • Andersson, U.1    Wang, H.2    Palmblad, K.3    Aveberger, A.C.4    Bloom, O.5
  • 9
    • 19944431800 scopus 로고    scopus 로고
    • RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages
    • pmid: 15644117
    • Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, et al. (2005) RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand J Immunol 61:1-9. pmid: 15644117 doi: 10.1111/j.0300-9475.2005.01534.x
    • (2005) Scand J Immunol , vol.61 , pp. 1-9
    • Kokkola, R.1    Andersson, A.2    Mullins, G.3    Ostberg, T.4    Treutiger, C.J.5
  • 10
    • 0037376222 scopus 로고    scopus 로고
    • Activation of gene expression in human neutrophils by high mobility group box 1 protein
    • pmid:12620891
    • Park JS, Arcaroli J, Yum HK, Yang H, Wang H, et al. (2003) Activation of gene expression in human neutrophils by high mobility group box 1 protein. Am J Physiol Cell Physiol 284:C870-879. pmid:12620891 doi: 10.1152/ajpcell.00322.2002
    • (2003) Am J Physiol Cell Physiol , vol.284 , pp. C870-C879
    • Park, J.S.1    Arcaroli, J.2    Yum, H.K.3    Yang, H.4    Wang, H.5
  • 11
    • 0037769813 scopus 로고    scopus 로고
    • Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells
    • pmid: 12456506
    • Fiuza C, Bustin M, Talwar S, Tropea M, Gerstenberger E, et al. (2003) Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood 101:2652-2660. pmid: 12456506 doi: 10.1182/blood-2002-05-1300
    • (2003) Blood , vol.101 , pp. 2652-2660
    • Fiuza, C.1    Bustin, M.2    Talwar, S.3    Tropea, M.4    Gerstenberger, E.5
  • 12
    • 2942700201 scopus 로고    scopus 로고
    • High mobility group box protein 1: An endogenous signal for dendritic cell maturation and Th1 polarization
    • pmid:15210788
    • Messmer D, Yang H, Telusma G, Knoll F, Li J, et al. (2004) High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization. J Immunol 173:307-313. pmid:15210788 doi: 10.4049/jimmunol.173.1.307
    • (2004) J Immunol , vol.173 , pp. 307-313
    • Messmer, D.1    Yang, H.2    Telusma, G.3    Knoll, F.4    Li, J.5
  • 13
    • 67650493786 scopus 로고    scopus 로고
    • Novel HMGB1-inhibiting therapeutic agents for experimental sepsis
    • pmid: 19333143
    • Wang H, Ward MF, Sama AE (2009) Novel HMGB1-inhibiting therapeutic agents for experimental sepsis. Shock 32:348-357. doi: 10.1097/SHK.0b013e3181 a551 bd. pmid: 19333143
    • (2009) Shock , vol.32 , pp. 348-357
    • Wang, H.1    Ward, M.F.2    Sama, A.E.3
  • 15
    • 34250837518 scopus 로고    scopus 로고
    • A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA
    • pmid: 17548579
    • Ivanov S, Dragoi A-M, Wang X, Dallacosta C, Louten J, et al. (2007) A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood 110:1970-1981. pmid: 17548579 doi: 10.1182/blood-2006-09-044776
    • (2007) Blood , vol.110 , pp. 1970-1981
    • Ivanov, S.1    Dragoi, A.-M.2    Wang, X.3    Dallacosta, C.4    Louten, J.5
  • 16
    • 84863828722 scopus 로고    scopus 로고
    • High mobility group box-1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K/Akt pathway activation
    • pmid:21698364
    • Yang J, Chen L, Yang J, Ding J, Rong H, et al. (2012) High mobility group box-1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K/Akt pathway activation. Mol Biol Rep 39:3361-3367. doi: 10.1007/s11033-011-1106-6. pmid:21698364
    • (2012) Mol Biol Rep , vol.39 , pp. 3361-3367
    • Yang, J.1    Chen, L.2    Yang, J.3    Ding, J.4    Rong, H.5
  • 17
    • 77952307233 scopus 로고    scopus 로고
    • Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease
    • pmid:20133931
    • Ferhani N, Letuve S, Kozhich A, Thibaudeau O, Grandsaigne M, et al. (2010) Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 181:917-927. doi: 10.1164/rccm.200903-0340OC. pmid:20133931
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 917-927
    • Ferhani, N.1    Letuve, S.2    Kozhich, A.3    Thibaudeau, O.4    Grandsaigne, M.5
  • 18
    • 54049139979 scopus 로고    scopus 로고
    • Potential role of high mobility group box 1 in cystic fibrosis airway disease
    • pmid:18658107
    • Rowe SM, Jackson PL, Liu G, Hardison M, Livraghi A, et al. (2008) Potential role of high mobility group box 1 in cystic fibrosis airway disease. Am J Respir Crit Care Med 178:822-831. doi: 10.1164/rccm.200712-1894OC pmid:18658107
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 822-831
    • Rowe, S.M.1    Jackson, P.L.2    Liu, G.3    Hardison, M.4    Livraghi, A.5
  • 19
    • 53349099086 scopus 로고    scopus 로고
    • The role of high mobility group box1 in pulmonary fibrosis
    • pmid:18441281
    • Hamada N, Maeyama T, Kawaguchi T, Yoshimi M, Fukumoto J, et al. (2008) The role of high mobility group box1 in pulmonary fibrosis. Am J Respir Cell Mol Biol 39:440-447. doi: 10.1165/rcmb.2007-0330OC. pmid:18441281
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 440-447
    • Hamada, N.1    Maeyama, T.2    Kawaguchi, T.3    Yoshimi, M.4    Fukumoto, J.5
  • 20
    • 84884670778 scopus 로고    scopus 로고
    • Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma
    • pmid:23948063
    • Lee CC, Lai YT, Chang HT, Liao JW, Shyu WC, et al. (2013) Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma. Biochem Pharmacol 86:940-949. doi: 10.1016/j.bcp. 2013.08.003. pmid:23948063
    • (2013) Biochem Pharmacol , vol.86 , pp. 940-949
    • Lee, C.C.1    Lai, Y.T.2    Chang, H.T.3    Liao, J.W.4    Shyu, W.C.5
  • 21
    • 84862813185 scopus 로고    scopus 로고
    • Motorcycle exhaust particles up-regulate expression of vascular adhesion molecule-1 and intercellular adhesion molecule-1 in human umbilical vein endothelial cells
    • pmid:22313677
    • Lee CC, Huang SH, Yang YT, Cheng YW, Li CH, et al. (2012) Motorcycle exhaust particles up-regulate expression of vascular adhesion molecule-1 and intercellular adhesion molecule-1 in human umbilical vein endothelial cells. Toxicol In Vitro 26:552-560. doi: 10.1016/j.tiv. 2012.01.021. pmid:22313677
    • (2012) Toxicol in Vitro , vol.26 , pp. 552-560
    • Lee, C.C.1    Huang, S.H.2    Yang, Y.T.3    Cheng, Y.W.4    Li, C.H.5
  • 22
    • 84883631190 scopus 로고    scopus 로고
    • Ovatodiolide inhibits the maturation of allergen-induced bone marrow-derived dendritic cells and induction of Th2 cell differentiation
    • pmid:24001794
    • Rao YK, Chen YC, Fang SH, Lai CH, Geethangili M, et al. (2013) Ovatodiolide inhibits the maturation of allergen-induced bone marrow-derived dendritic cells and induction of Th2 cell differentiation. Int Immunopharmacol 17:617-624. doi: 10.1016/j.intimp. 2013.08.002. pmid:24001794
    • (2013) Int Immunopharmacol , vol.17 , pp. 617-624
    • Rao, Y.K.1    Chen, Y.C.2    Fang, S.H.3    Lai, C.H.4    Geethangili, M.5
  • 23
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • pmid:17406593
    • Liang CC, Park AY, Guan JL (2007) In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protocols 2:329-333. pmid:17406593 doi: 10.1038/nprot.2007.30
    • (2007) Nat Protocols , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 25
    • 80052037008 scopus 로고    scopus 로고
    • Shikonin inhibited mitogen-activated IL-4 and IL-5 production on EL-4 cells through downregulation of GATA-3 and c-Maf induction
    • pmid:21806999
    • Lee CC, Kang JJ, Chiang BL, Wang CN, Cheng YW (2011) Shikonin inhibited mitogen-activated IL-4 and IL-5 production on EL-4 cells through downregulation of GATA-3 and c-Maf induction. Life Sci 89:364-370. doi: 10.1016/j.lfs.2011.07.002. pmid:21806999
    • (2011) Life Sci , vol.89 , pp. 364-370
    • Lee, C.C.1    Kang, J.J.2    Chiang, B.L.3    Wang, C.N.4    Cheng, Y.W.5
  • 26
    • 84866355652 scopus 로고    scopus 로고
    • Antiallergic asthma properties of brazilin through inhibition of TH2 responses in T cells and in a murine model of asthma
    • pmid:22920671
    • Lee CC, Wang CN, Kang JJ, Liao JW, Chiang BL, et al. (2012) Antiallergic asthma properties of brazilin through inhibition of TH2 responses in T cells and in a murine model of asthma. J Agric Food Chem 60:9405-9414. pmid:22920671 doi: 10.1021/jf2038778
    • (2012) J Agric Food Chem , vol.60 , pp. 9405-9414
    • Lee, C.C.1    Wang, C.N.2    Kang, J.J.3    Liao, J.W.4    Chiang, B.L.5
  • 27
    • 79960726338 scopus 로고    scopus 로고
    • High mobility group protein B1 (HMGB1) in Asthma: Comparison of patients with chronic obstructive pulmonary disease and healthy controls
    • pmid:21380479
    • Hou C, Zhao H, Liu L, Li W, Zhou X, et al. (2011) High mobility group protein B1 (HMGB1) in Asthma: comparison of patients with chronic obstructive pulmonary disease and healthy controls. Mol Med 17:807-815. doi: 10.2119/molmed.2010.00173. pmid:21380479
    • (2011) Mol Med , vol.17 , pp. 807-815
    • Hou, C.1    Zhao, H.2    Liu, L.3    Li, W.4    Zhou, X.5
  • 28
    • 67650218306 scopus 로고    scopus 로고
    • Osteopontin induces airway remodeling and lung fibroblast activation in a murine model of asthma
    • pmid:19151319
    • Kohan M, Breuer R, Berkman N (2009) Osteopontin induces airway remodeling and lung fibroblast activation in a murine model of asthma. Am J Respir Cell Mol Biol 41:290-296. doi: 10.1165/rcmb.2008-0307OC. pmid:19151319
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 290-296
    • Kohan, M.1    Breuer, R.2    Berkman, N.3
  • 29
    • 41049117932 scopus 로고    scopus 로고
    • Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)
    • pmid:18264787
    • Van Beijnum JR, Buurman WA, Griffioen AW (2008) Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis 11:91-99. doi: 10.1007/s10456-008-9093-5. pmid:18264787
    • (2008) Angiogenesis , vol.11 , pp. 91-99
    • Van Beijnum, J.R.1    Buurman, W.A.2    Griffioen, A.W.3
  • 30
    • 84864866406 scopus 로고    scopus 로고
    • Into the matrix: Targeting fibroblasts in pulmonary fibrosis
    • pmid:22847104
    • Sivakumar P, Ntolios P, Jenkins G, Laurent G (2012) Into the matrix: targeting fibroblasts in pulmonary fibrosis. Curr Opin Pulm Med 18:462-469. doi: 10.1097/MCP.0b013e328356800f. pmid:22847104
    • (2012) Curr Opin Pulm Med , vol.18 , pp. 462-469
    • Sivakumar, P.1    Ntolios, P.2    Jenkins, G.3    Laurent, G.4
  • 31
    • 26644438095 scopus 로고    scopus 로고
    • Role of matrix metalloproteinases in the development of airway inflammation and remodeling
    • pmid:16172745
    • Lagente V, Manoury B, Nenan S, Le Quement C, Martin-Chouly C, et al. (2005) Role of matrix metalloproteinases in the development of airway inflammation and remodeling. Braz J Med Biol Res 38:1521-1530. pmid:16172745 doi: 10.1590/s0100-879x2005001000009
    • (2005) Braz J Med Biol Res , vol.38 , pp. 1521-1530
    • Lagente, V.1    Manoury, B.2    Nenan, S.3    Le Quement, C.4    Martin-Chouly, C.5
  • 32
    • 4043161974 scopus 로고    scopus 로고
    • Mitochondrial redox control of matrix metalloproteinases
    • pmid:15304253
    • Nelson KK, Melendez JA (2004) Mitochondrial redox control of matrix metalloproteinases. Free Radic Biol Med 37:768-784 pmid:15304253 doi: 10.1016/j.freeradbiomed.200406.008
    • (2004) Free Radic Biol Med , vol.37 , pp. 768-784
    • Nelson, K.K.1    Melendez, J.A.2
  • 33
    • 33846785537 scopus 로고    scopus 로고
    • Matrix metalloproteinases in lung: Multiple, multifarious, and multifaceted
    • pmid:17237343
    • Greenlee KJ, Werb Z, Kheradmand F (2007) Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev 87:69-98. pmid:17237343 doi: 10.1152/physrev. 00022.2006
    • (2007) Physiol Rev , vol.87 , pp. 69-98
    • Greenlee, K.J.1    Werb, Z.2    Kheradmand, F.3
  • 34
    • 84865173127 scopus 로고    scopus 로고
    • The role of high-mobility group box-1 (HMGB1) in the pathogenesis of asthma
    • pmid:22909167
    • Shim EJ, Chun E, Lee HS, Bang BR, Kim TW, et al. (2012) The role of high-mobility group box-1 (HMGB1) in the pathogenesis of asthma. Clin Exp Allergy 42:958-965. doi: 10.1111/j.1365-2222.2012.03998.x. pmid:22909167
    • (2012) Clin Exp Allergy , vol.42 , pp. 958-965
    • Shim, E.J.1    Chun, E.2    Lee, H.S.3    Bang, B.R.4    Kim, T.W.5
  • 35
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis: Therapeutic translation for fibrotic disease
    • pmid:22772564
    • Wynn TA, Ramalingam TR (2012) Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med 18:1028-1040. doi: 10.1038/nm.2807. pmid:22772564
    • (2012) Nat Med , vol.18 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 36
    • 0242319836 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. Prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation
    • pmid:12738687
    • Kolodsick JE, Peters-Golden M, Larios J, Toews GB, Thannickal VJ, et al. (2003) Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation. Am J Respir Cell Mol Biol 29:537-544 pmid:12738687 doi: 10.1165/rcmb.2002-0243oc
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 537-544
    • Kolodsick, J.E.1    Peters-Golden, M.2    Larios, J.3    Toews, G.B.4    Thannickal, V.J.5
  • 37
    • 33748189347 scopus 로고    scopus 로고
    • Cell-surface association between matrix metalloproteinases and integrins: Role of the complexes in leukocyte migration and cancer progression
    • pmid:16609063
    • Stefanidakis M, Koivunen E (2006) Cell-surface association between matrix metalloproteinases and integrins: role of the complexes in leukocyte migration and cancer progression. Blood 108:1441-1450. pmid:16609063 doi: 10.1182/blood-2006-02-005363
    • (2006) Blood , vol.108 , pp. 1441-1450
    • Stefanidakis, M.1    Koivunen, E.2
  • 38
    • 39449091122 scopus 로고    scopus 로고
    • Osteopontin expression is required for myofibroblast differentiation
    • pmid:18079410
    • Lenga Y, Koh A, Perera AS, McCulloch CA, Sodek J, et al. (2008) Osteopontin expression is required for myofibroblast differentiation. Circ Res 102:319-327. pmid:18079410 doi: 10.1161/circresaha.107.160408
    • (2008) Circ Res , vol.102 , pp. 319-327
    • Lenga, Y.1    Koh, A.2    Perera, A.S.3    McCulloch, C.A.4    Sodek, J.5
  • 39
    • 78651442474 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase signalling and ERK1/2 bistability in asthma
    • pmid:21121982
    • Alam R, Gorska MM (2011) Mitogen-activated protein kinase signalling and ERK1/2 bistability in asthma. Clin Exp Allergy 41:149-159. doi: 10.1111/j.1365-2222.2010.03658.x. pmid:21121982
    • (2011) Clin Exp Allergy , vol.41 , pp. 149-159
    • Alam, R.1    Gorska, M.M.2
  • 40
    • 33746731651 scopus 로고    scopus 로고
    • HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
    • pmid:16878026
    • Yu M, Wang H, Ding A, Golenbock DT, Latz E, et al. (2006) HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock 26:174-179. pmid:16878026 doi: 10.1097/01.shk.0000225404.51320.82
    • (2006) Shock , vol.26 , pp. 174-179
    • Yu, M.1    Wang, H.2    Ding, A.3    Golenbock, D.T.4    Latz, E.5


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