Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma

Biochemical Pharmacology

Volumn 86, Issue 7, 2013, Pages 940-949

  Lee, Chen Chen ^a,b   Lai, Yu Ting ^b   Chang, Hao Teng ^b   Liao, Jiunn Wang ^c   Shyu, Woei Cherng ^b   Li, Chi Yuan ^b   Wang, Chien Neng ^b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Airway inflammation; Airway remodeling; HMGB1; IL 17

Indexed keywords

COLLAGEN; GAMMA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; NEUTRALIZING ANTIBODY; OVALBUMIN; PROTEIN; RAGE PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AIRWAY REMODELING; AIRWAY RESISTANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; FEMALE; LUNG PARENCHYMA; MEDIASTINUM LYMPH NODE; MOUSE; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RESPIRATORY TRACT INFLAMMATION; TH1 CELL; TH17 CELL; TH2 CELL; THERAPY EFFECT;

AIRWAY INFLAMMATION; AIRWAY REMODELING; HMGB1; IL-17;

AIRWAY RESISTANCE; ANIMALS; ANTIBODIES, NEUTRALIZING; ASTHMA; BRONCHITIS; BRONCHOALVEOLAR LAVAGE FLUID; CHRONIC DISEASE; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HMGB1 PROTEIN; LUNG; MICE; MICE, INBRED BALB C; OVALBUMIN; PNEUMONIA; RABBITS; TH1 CELLS; TH17 CELLS; TH2 CELLS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84884670778     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.08.003     Document Type: Article

References (56)

1. W.W. Busse, and R.F.J. Lermanske Asthma New England Journal of Medicine 344 2001 350 362 (Pubitemid 32107645)
2. D.T. Umetsu, J.J. Mclntire, O. Akbari, C. Macaubas, and R.H. Dekruyff Asthma: an epidemic of dysregulated immunity Nature Immunology 3 2002 715 720
3. K.F. Chung, and P.J. Barnes Cytokines in asthma Thorax 54 1999 825
4. M. Wills-karp Immunologic basis of antigen-induced airway hyperresponsiveness Annual Review of Immunology 17 1999 255
5. R.H. Wilson, G.S. Whitehead, H. Nakano, M.E. Free, J.K. Kolls, and D.N. Cook Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness American Journal of Respiratory and Critical Care Medicine 180 2009 720 730
6. W. Al-Ramli, D. Préfontaine, F. Chouiali, J.G. Martin, R. Olivenstein, and C. Lemière TH17-associated cytokines (IL-17A and IL-17F) in severe asthma Journal of Allergy and Clinical Immunology 123 2009 1185 1187
7. M. Pelletier, L. Maggi, A. Micheletti, E. Lazzeri, N. Tamassia, and C. Costantini Evidence for a cross-talk between human neutrophils and Th17 cells Blood 115 2010 335 343
8. J. Monteseirin Neutrophils and asthma Journal of Investigational Allergology & Clinical Immunology 19 2009 340 354
9. G.H. Goodwin, C. Sanders, and E.W. Johns A new group of chromatin-associated proteins with a high content of acidic and basic amino acids European Journal of Biochemistry 38 1973 14 19
10. H. Wang, O. Bloom, M. Zhang, J.M. Vishnubhakat, M. Ombrellino, and J. Che HMG-1 as a late mediator of endotoxin lethality in mice Science 285 1999 248 251 (Pubitemid 29329996)
11. P.L. Sappington, R. Yang, H. Yang, K.J. Tracey, R.L. Delude, and M.P. Fink HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice Gastroenterology 123 2002 790 802 (Pubitemid 34977085)
12. T. Hamada, M. Torikai, A. Kuwazuru, M. Tanaka, N. Horai, and T. Fukuda Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis Arthritis and Rheumatism 58 2008 2675 2685
13. K.A. O'Connor, M.K. Hansen, C. Rachal Pugh, M.M. Deak, J.C. Biedenkapp, and E.D. Milligan Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects Cytokine 24 2003 254 265 (Pubitemid 37373661)
14. N. Ferhani, S. Letuve, A. Kozhich, O. Thibaudeau, M. Grandsaigne, and M. Maret Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease American Journal of Respiratory and Critical Care Medicine 181 2010 917 927
15. N. Hamada, T. Maeyama, T. Kawaguchi, M. Yoshimi, J. Fukumoto, and M. Yamada The role of high mobility group box1 in pulmonary fibrosis American Journal of Respiratory Cell and Molecular Biology 39 2008 440 447
16. H. Yang, H. Wang, J.C. Christopher, and K.J. Tracey The cytokine activity of HMGB1 Journal of Leukocyte Biology 78 2005 1 8 (Pubitemid 40979937)
17. S. Ivanov, A.-M. Dragoi, X. Wang, C. Dallacosta, J. Louten, and G. Musco A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA Blood 110 2007 1970 1981 (Pubitemid 47443911)
18. J. Yang, L. Chen, J. Ding, H. Rong, W. Dong, and X. Li High mobility group box-1 induces migration of vascular smooth muscle cells via TLR4-dependent PI3K/Akt pathway activation Molecular Biology Reports 39 2012 3361 3367
19. T. Watanabe, K. Asai, H. Fujimoto, H. Tanaka, H. Kanazawa, and K. Hirata Increased levels of HMGB-1 and endogenous secretory RAGE in induced sputum from asthmatic patients Respiratory Medicine 105 2011 519 525
20. E.J. Shim, E. Chun, H.S. Lee, B.R. Bang, T.W. Kim, and S.H. Cho The role of high-mobility group box-1 (HMGB1) in the pathogenesis of asthma Clinical and Experimental Allergy 42 2012 958 965
21. A.J. Sandford, T. Chagani, S. Zhu, T.D. Weir, T.R. Bai, and J.J. Spinelli Polymorphisms in the IL4, IL4RA, and FCERIB genes and asthma severity Journal of Allergy and Clinical Immunology 106 2000 135 140 (Pubitemid 30482863)
22. V. Siroux, I. Pin, M.P. Oryszczyn, N. LeMoual, and F. Kauffmann Relationships of active smoking to asthma and asthma severity in the EGEA study. Epidemiological study on the Genetics and Environment of Asthma European Respiratory Journal 15 2000 470 477 (Pubitemid 30158183)
23. R.L. Evans, A.T. Nials, R.G. Knowles, E.J. Kidd, W.R. Ford, and K.J. Broadley A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma Pulmonary Pharmacology and Therapeutics 25 2012 453 464
24. M. Wegmann, H. Fehrenbach, A. Fehrenbach, T. Held, C. Schramm, and H. Garn Involvement of distal airways in a chronic model of experimental asthma Clinical and Experimental Allergy 35 2005 1263 1271
25. E. Di Valentin, C. Crahay, N. Garbacki, B. Hennuy, M. Gueders, and A. Noel New asthma biomarkers: lessons from murine models of acute and chronic asthma American Journal of Physiology - Lung Cellular and Molecular Physiology 296 2009 L185 L197
26. S.J. McMillan, and C.M. Lloyd Prolonged allergen challenge in mice leads to persistent airway remodelling Clinical and Experimental Allergy 34 2004 497 507 (Pubitemid 38373015)
27. J. Chakir, J. Shannon, S. Molet, M. Fukakusa, J. Elias, and M. Laviolette Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression Journal of Allergy and Clinical Immunology 111 2003 1293 1298 (Pubitemid 36683685)
28. S.M. Molet, Q.A. Hamid, and D.L. Hamilos IL-11 and IL-17 expression in nasal polyps: relationship to collagen deposition and suppression by intranasal fluticasone propionate Laryngoscope 113 2003 1803 1812 (Pubitemid 37210986)
29. D.C. Simoes, G. Xanthou, K. Petrochilou, V. Panoutsakopoulou, C. Roussos, and C. Gratziou Osteopontin deficiency protects against airway remodeling and hyperresponsiveness in chronic asthma American Journal of Respiratory and Critical Care Medicine 179 2009 894 902
30. C.C. Lee, H.Y. Huang, and B.L. Chiang Lentiviral-mediated interleukin-4 and interleukin-13 RNA interference decrease airway inflammation and hyperresponsiveness Human Gene Therapy 22 2011 577 586
31. C.C. Lee, C.N. Wang, Y.T. Lai, J.J. Kang, J.W. Liao, and B.L. Chiang Shikonin inhibits maturation of bone marrow-derived dendritic cells and suppresses allergic airway inflammation in a murine model of asthma British Journal of Pharmacology 161 2010 1496 1511
32. B. Degryse, T. Bonaldi, P. Scaffidi, S. Muller, M. Resnati, and F. Sanvito The high mobility group (HMG) boxenuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells Journal of Cell Biology 152 2001 1197 1206 (Pubitemid 34280177)
33. S.S. Wagers, H.C. Haverkamp, J.H.T. Bates, R.J. Norton, J.A. Thompson-Figueroa, and M.J. Sullivan Intrinsic and antigen-induced airway hyperresponsiveness are the result of diverse physiological mechanisms Journal of Applied Physiology 102 2007 221 230 (Pubitemid 46089770)
34. C.C. Lee, J.J. Kang, B.L. Chiang, C.N. Wang, and Y.W. Cheng Shikonin inhibited mitogen-activated IL-4 and IL-5 production on EL-4 cells through downregulation of GATA-3 and c-Maf induction Life Sciences 89 2011 364 370
35. I.E. Dumitriu, P. Baruah, B. Valentinis, R.E. Voll, M. Herrmann, and P.P. Nawroth Release of high mobility group box 1 by dendritic cells controls T cell activation via the receptor for advanced clycation end products Journal of Immunology 174 2005 7506 7515 (Pubitemid 40806253)
36. C. Semino, G. Angelini, A. Poggi, and A. Rubartelli NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1 Blood 106 2005 609 616 (Pubitemid 40981258)
37. G. Chen, J. Li, M. Ochani, B. Rendon-Mitchell, X. Qiang, and S. Susarla Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms Journal of Leukocyte Biology 76 2004 994 1001 (Pubitemid 39462000)
38. P.C. Fulkerson, N. Zimmermann, L.M. Hassman, F.D. Finkelman, and M.E. Rothenberg Pulmonary chemokine expression is coordinately regulated by STAT1, STAT6, and IFN-gamma Journal of Immunology 173 2004 7565 7574 (Pubitemid 39628198)
39. G. Hansen, G. Berry, R.H. DeKruyff, and D.T. Umetsu Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation Journal of Clinical Investigation 103 1999 175 183 (Pubitemid 29053135)
40. D.A. Randolph, R. Stephens, C.J. Carruthers, and D.D. Chaplin Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation Journal of Clinical Investigation 104 1999 1021 1029 (Pubitemid 29536312)
41. Y. Shi, S. Sandoghchian Shotorbani, Z. Su, Y. Liu, J. Tong, and D. Zheng Enhanced HMGB1 expression may contribute to Th17 cells activation in rheumatoid arthritis Clinical and Developmental Immunology 2012 2012 295081
42. Z. Su, C. Sun, C. Zhou, Y. Liu, H. Zhu, and S. Sandoghchian HMGB1 blockade attenuates experimental autoimmune myocarditis and suppresses Th17-cell expansion European Journal of Immunology 41 2011 3586 3595
43. D. Yang, Q. Chen, H. Yang, K.J. Tracey, M. Bustin, and J.J. Oppenheim High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin Journal of Leukocyte Biology 81 2007 59 66 (Pubitemid 46021253)
44. D. Messmer, H. Yang, G. Telusma, F. Knoll, J. Li, and B. Messmer High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization Journal of Immunology 173 2004 307 313 (Pubitemid 38797355)
45. C.S. Park, B.R. Bang, H.S. Kwon, K.A. Moon, T.B. Kim, and K.Y. Lee Metformin reduces airway inflammation and remodeling via activation of AMP-activated protein kinase Biochemical Pharmacology 84 2012 1660 1670
46. T. Nabe, F. Hosokawa, K. Matsuya, T. Morishita, A. Ikedo, and M. Fujii Important role of neutrophils in the late asthmatic response in mice Life Sciences 88 2011 1127 1135
47. S.T. Holgate, J. Holloway, S. Wilson, P.H. Howarth, H.M. Haitchi, and S. Babu Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities Journal of Allergy and Clinical Immunology 117 2006 496 506
48. V.V. Orlova, E.Y. Choi, C. Xie, E. Chavakis, A. Bierhaus, and E. Ihanus A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin EMBO Journal 26 2007 1129 1139
49. A.B. Kaya, S. Phippsa, and D.S. Robinson A role for eosinophils in airway remodelling in asthma Trends in Immunology 25 2004 477 482 (Pubitemid 39490254)
50. A. Trompette, S. Divanovic, A. Visintin, C. Blanchard, R.S. Hegde, and R. Madan Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein Nature 457 2009 585 588
51. K.F. Buckland, E. O'Connor, L.A. Murray, and C.M. Hogaboam Toll like receptor-2 modulates both innate and adaptive immune responses during chronic fungal asthma in mice Inflammation Research 57 2008 379 387
52. P.S. Milutinovic, J.F. Alcorn, J.M. Englert, L.T. Crum, and T.D. Oury The receptor for advanced glycation end products is a central mediator of asthma pathogenesis American Journal of Pathology 181 2012 1215 1225
53. S.T. Buckley, and C. Ehrhardt The receptor for advanced glycation end products (RAGE) and the lung Journal of Biomedicine and Biotechnology 2010 2010 917108
54. J.M. Englert, L.E. Hanford, N. Kaminski, J.M. Tobolewski, R.J. Tan, and C.L. Fattman A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis American Journal of Pathology 172 2008 583 591 (Pubitemid 351354532)
55. M. He, H. Kubo, K. Ishizawa, A.E. Hegab, Y. Yamamoto, and H. Yamamoto The role of the receptor for advanced glycation end-products in lung fibrosis American Journal of Physiology - Lung Cellular and Molecular Physiology 293 2007 L1427 L1436
56. D. Tang, R. Kang, W. Xiao, H. Zhang, M.T. Lotze, and H. Wang Quercetin prevents LPS-induced high mobility group box 1 release and proinflammatory function American Journal of Respiratory Cell and Molecular Biology 41 2009 651 660