Newborn hypoxia/anoxia inhibits cardiomyocyte proliferation and decreases cardiomyocyte endowment in the developing heart: Role of endothelin-1

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Paradis, Alexandra N ^a   Gay, Maresha S ^a   Wilson, Christopher G ^a,b   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 METHOXYPHENYL) 2 (3,4 METHYLENEDIOXYPHENYL) 4 OXO 3 (3,4,5 TRIMETHOXYBENZYL) 2 BUTENOIC ACID; CYCLIN D2; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEIN P27; 1,3 DIOXOLANE DERIVATIVE; CYCLINE; ENDOTHELIN A RECEPTOR ANTAGONIST; HIF1A PROTEIN, RAT; P27 ANTIGEN; PROENDOTHELIN 1; PROTEIN PRECURSOR;

ANALYTICAL PARAMETERS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOCYTE BINUCLEATION; CARDIOMYOCYTE ENDOWMENT; CARDIOMYOCYTE NUMBER PER HEART WEIGHT; CARDIOVASCULAR PARAMETERS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SIZE; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; COMPARATIVE STUDY; CONTROLLED STUDY; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART SIZE; HEART TO BODY WEIGHT RATIO; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; ISOLATED HEART; MOLECULAR DYNAMICS; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; ANIMAL; BODY WEIGHT; CARDIAC MUSCLE CELL; CELL COUNT; CELL HYPOXIA; CYTOLOGY; DRUG EFFECTS; EMBRYOLOGY; FEMALE; FETUS HEART; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; ORGAN SIZE; PREGNANCY; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; CELL COUNT; CELL HYPOXIA; CELL PROLIFERATION; CELL SIZE; DIOXOLES; ENDOTHELIN A RECEPTOR ANTAGONISTS; ENDOTHELIN-1; FEMALE; FETAL HEART; GENE EXPRESSION REGULATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MYOCYTES, CARDIAC; ORGAN SIZE; PREGNANCY; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RNA, MESSENGER;

EID: 84923271024     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116600     Document Type: Article

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