메뉴 건너뛰기




Volumn 23, Issue 24, 2003, Pages 9032-9045

Anoxic Fibroblasts Activate a Replication Checkpoint that Is Bypassed by E1a

Author keywords

[No Author keywords available]

Indexed keywords

E1A PROTEIN; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN P53; TRANSCRIPTION FACTOR E2F;

EID: 0344197968     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.24.9032-9045.2003     Document Type: Article
Times cited : (22)

References (56)
  • 1
    • 0032531871 scopus 로고    scopus 로고
    • A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1)
    • Alevizopoulos, K., B. Catarin, J. Vlach, and B. Amati. 1998. A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1). EMBO J. 17:5987-5997.
    • (1998) EMBO J. , vol.17 , pp. 5987-5997
    • Alevizopoulos, K.1    Catarin, B.2    Vlach, J.3    Amati, B.4
  • 2
    • 0028035447 scopus 로고
    • Regulation of cell proliferation under extreme and moderate hypoxia: The role of pyrimidine (deoxy)nucleotides
    • Amellem, O., M. Loffler, and E. O. Pettersen. 1994. Regulation of cell proliferation under extreme and moderate hypoxia: the role of pyrimidine (deoxy)nucleotides. Br. J. Cancer 70:857-866.
    • (1994) Br. J. Cancer , vol.70 , pp. 857-866
    • Amellem, O.1    Loffler, M.2    Pettersen, E.O.3
  • 3
    • 0031936129 scopus 로고    scopus 로고
    • The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoprotein
    • Amellem, O., J. A. Sandvik, T. Stokke, and E. O. Pettersen. 1998. The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoprotein. Br. J. Cancer 77:862-872.
    • (1998) Br. J. Cancer , vol.77 , pp. 862-872
    • Amellem, O.1    Sandvik, J.A.2    Stokke, T.3    Pettersen, E.O.4
  • 4
    • 0025730640 scopus 로고
    • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
    • Andrews, N. C., and D. V. Faller. 1991. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19:2499.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 2499
    • Andrews, N.C.1    Faller, D.V.2
  • 7
    • 0026508007 scopus 로고
    • DNA double labelling with IdUrd and CIdUrd for spatial and temporal analysis of cell proliferation and DNA replication
    • Aten, J. A., P. J. Bakker, J. Stap, G. A. Boschman, and C. H. Veenhof. 1992. DNA double labelling with IdUrd and CIdUrd for spatial and temporal analysis of cell proliferation and DNA replication. Histochem. J. 24:251-259.
    • (1992) Histochem. J. , vol.24 , pp. 251-259
    • Aten, J.A.1    Bakker, P.J.2    Stap, J.3    Boschman, G.A.4    Veenhof, C.H.5
  • 8
    • 0037325853 scopus 로고    scopus 로고
    • Deregulated degradation of the cdk inhibitor p27 and malignant transformation
    • Bloom, J., and M. Pagano. 2003. Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Semin. Cancer Biol. 13:41-47.
    • (2003) Semin. Cancer Biol. , vol.13 , pp. 41-47
    • Bloom, J.1    Pagano, M.2
  • 9
    • 0031046410 scopus 로고    scopus 로고
    • Role of ribonucleotide reductase and deoxynucleotide pools in the oxygen-dependent control of DNA replication in Ehrlich ascites cells
    • Brischwein, K., M. Engelcke, H. J. Riedinger, and H. Probst. 1997. Role of ribonucleotide reductase and deoxynucleotide pools in the oxygen-dependent control of DNA replication in Ehrlich ascites cells. Eur. J. Biochem. 244:286-293.
    • (1997) Eur. J. Biochem. , vol.244 , pp. 286-293
    • Brischwein, K.1    Engelcke, M.2    Riedinger, H.J.3    Probst, H.4
  • 12
    • 0036305474 scopus 로고    scopus 로고
    • Distinct roles for cyclins E and A during DNA replication complex assembly and activation
    • Coverley, D., H. Laman, and R. A. Laskey. 2002. Distinct roles for cyclins E and A during DNA replication complex assembly and activation, Nat. Cell Biol. 4:523-528.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 523-528
    • Coverley, D.1    Laman, H.2    Laskey, R.A.3
  • 13
    • 85047692887 scopus 로고    scopus 로고
    • Expansion of human SCID-repopulating cells under hypoxic conditions
    • Danet, G. H., Y. Pan, J. L. Luongo, D. A. Bonnet, and M. C. Simon. 2003. Expansion of human SCID-repopulating cells under hypoxic conditions. J. Clin. Investig. 112:126-135.
    • (2003) J. Clin. Investig. , vol.112 , pp. 126-135
    • Danet, G.H.1    Pan, Y.2    Luongo, J.L.3    Bonnet, D.A.4    Simon, M.C.5
  • 16
    • 0031835957 scopus 로고    scopus 로고
    • Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein
    • Ebert, B. L., and H. F. Bunn. 1998. Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein. Mol. Cell. Biol. 18:4089-4096.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4089-4096
    • Ebert, B.L.1    Bunn, H.F.2
  • 17
    • 0035802112 scopus 로고    scopus 로고
    • Activation of mammalian Chk1 during DNA replication arrest: A role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing
    • Feijoo, C., C. Hall-Jackson, R. Wu, D. Jenkins, J. Leitch, D. M. Gilbert, and C. Smythe. 2001. Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing. J. Cell Biol. 154:913-923.
    • (2001) J. Cell Biol. , vol.154 , pp. 913-923
    • Feijoo, C.1    Hall-Jackson, C.2    Wu, R.3    Jenkins, D.4    Leitch, J.5    Gilbert, D.M.6    Smythe, C.7
  • 18
    • 0022486653 scopus 로고
    • In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes
    • Franza, B. R., Jr., K. Maruyama, J. I. Garrels, and H. E. Ruley. 1986. In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell 44:409-418.
    • (1986) Cell , vol.44 , pp. 409-418
    • Franza Jr., B.R.1    Maruyama, K.2    Garrels, J.I.3    Ruley, H.E.4
  • 21
    • 0027198256 scopus 로고
    • Selective and synchronous activation of early-S-phase replicons of Ehrlich ascites cells
    • Gekeler, V., J. Epple, G. Kleymann, and H. Probst. 1993. Selective and synchronous activation of early-S-phase replicons of Ehrlich ascites cells. Mol. Cell. Biol. 13:5020-5033.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5020-5033
    • Gekeler, V.1    Epple, J.2    Kleymann, G.3    Probst, H.4
  • 22
    • 0034778671 scopus 로고    scopus 로고
    • Cdk pathway: Cyclin-dependent kinases and cyclin-dcpendent kinase inhibitors
    • Gitig, D. M., and A. Koff. 2001. Cdk pathway: cyclin-dependent kinases and cyclin-dcpendent kinase inhibitors. Mol. Biotechnol. 19:179-188.
    • (2001) Mol. Biotechnol. , vol.19 , pp. 179-188
    • Gitig, D.M.1    Koff, A.2
  • 24
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber, T. G., C. Osmanian, T. Jacks, D. E. Housman, C. J. Koch, S. W. Lowe, and A. J. Giaccia. 1996. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 379:88-91.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3    Housman, D.E.4    Koch, C.J.5    Lowe, S.W.6    Giaccia, A.J.7
  • 26
    • 0035145591 scopus 로고    scopus 로고
    • p21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest
    • Green, S. L., R. A. Freiberg, and A. J. Giaccia. 2001. p21(Cip1) and p27(Kip1) regulate cell cycle reentry after hypoxic stress but are not necessary for hypoxia-induced arrest. Mol. Cell. Biol. 21:1196-1206.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1196-1206
    • Green, S.L.1    Freiberg, R.A.2    Giaccia, A.J.3
  • 28
    • 0038146962 scopus 로고    scopus 로고
    • ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation
    • Hammond, E. M., M. J. Dorie, and A. J. Giaccia. 2003. ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation. J. Biol. Chem. 278:12207-12213.
    • (2003) J. Biol. Chem. , vol.278 , pp. 12207-12213
    • Hammond, E.M.1    Dorie, M.J.2    Giaccia, A.J.3
  • 29
    • 0026537277 scopus 로고
    • The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F
    • Hiebert, S. W., S. P. Chellappan, J. M. Horowitz, and J. R. Nevins. 1992. The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes Dev. 6:177-185.
    • (1992) Genes Dev. , vol.6 , pp. 177-185
    • Hiebert, S.W.1    Chellappan, S.P.2    Horowitz, J.M.3    Nevins, J.R.4
  • 30
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel, M., K. Schlenger, B. Aral, M. Mitze, U. Schaffer, and P. Vaupel. 1996. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 56:4509-4515.
    • (1996) Cancer Res. , vol.56 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schaffer, U.5    Vaupel, P.6
  • 31
    • 0034475166 scopus 로고    scopus 로고
    • Development of clinical trial of E1A gene therapy targeting HER-2/neu-overexpressing breast and ovarian cancer
    • Hung, M. C., G. N. Hortobagyi, and N. T. Ueno. 2000. Development of clinical trial of E1A gene therapy targeting HER-2/neu-overexpressing breast and ovarian cancer. Adv. Exp. Med. Biol. 465:171-180.
    • (2000) Adv. Exp. Med. Biol. , vol.465 , pp. 171-180
    • Hung, M.C.1    Hortobagyi, G.N.2    Ueno, N.T.3
  • 32
    • 0026021882 scopus 로고
    • Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product
    • Kaelin, W. G., Jr., D. C. Pallas, J. A. DeCaprio, F. J. Kaye, and D. M. Livingston. 1991. Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell 64:521-532.
    • (1991) Cell , vol.64 , pp. 521-532
    • Kaelin Jr., W.G.1    Pallas, D.C.2    DeCaprio, J.A.3    Kaye, F.J.4    Livingston, D.M.5
  • 34
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • Kowalik, T. F., J. DeGregori, J. K. Schwarz, and J. R. Nevins. 1995. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J. Virol. 69:2491-2500.
    • (1995) J. Virol. , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    DeGregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 35
    • 0032487925 scopus 로고    scopus 로고
    • Hypoxia-induced pRB hypophosphorylation results from downregulation of CDK and upregulation of PP1 activities
    • Krtolica, A., N. A. Krucher, and J. W. Ludlow. 1998. Hypoxia-induced pRB hypophosphorylation results from downregulation of CDK and upregulation of PP1 activities. Oncogene 17:2295-2304.
    • (1998) Oncogene , vol.17 , pp. 2295-2304
    • Krtolica, A.1    Krucher, N.A.2    Ludlow, J.W.3
  • 36
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • Kung, A. L., S. Wang, J. M. Klco, W. G. Kaelin, and D. M. Livingston. 2000. Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat. Med. 6:1335-1340.
    • (2000) Nat. Med. , vol.6 , pp. 1335-1340
    • Kung, A.L.1    Wang, S.2    Klco, J.M.3    Kaelin, W.G.4    Livingston, D.M.5
  • 37
    • 0024341665 scopus 로고
    • The biosynthetic pathway of pyrimidine (deoxy)nucleotides: A sensor of oxygen tension necessary for maintaining cell proliferation?
    • Loffier, M. 1989. The biosynthetic pathway of pyrimidine (deoxy)nucleotides: a sensor of oxygen tension necessary for maintaining cell proliferation? Exp. Cell Res. 182:673-680.
    • (1989) Exp. Cell Res. , vol.182 , pp. 673-680
    • Loffier, M.1
  • 39
    • 0027772296 scopus 로고
    • Disruption of cell-cycle control by viral oncoproteins
    • Nevins, J. R. 1993. Disruption of cell-cycle control by viral oncoproteins. Biochem. Soc. Trans. 21:935-938.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 935-938
    • Nevins, J.R.1
  • 40
    • 0032497588 scopus 로고    scopus 로고
    • Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F
    • Ohtani, K., A. Tsujimoto, M. Ikeda, and M. Nakamura. 1998. Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F. Oncogene 17:1777-1785.
    • (1998) Oncogene , vol.17 , pp. 1777-1785
    • Ohtani, K.1    Tsujimoto, A.2    Ikeda, M.3    Nakamura, M.4
  • 41
    • 0026655690 scopus 로고
    • Simian virus 40 large tumor antigen alone or two cooperating oncogenes convert REF52 cells to a state permissive for gene amplification
    • Perry, M. E., M. Commane, and G. R. Stark. 1992. Simian virus 40 large tumor antigen alone or two cooperating oncogenes convert REF52 cells to a state permissive for gene amplification. Proc. Natl. Acad. Sci. USA 89:8112-8116.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8112-8116
    • Perry, M.E.1    Commane, M.2    Stark, G.R.3
  • 43
    • 0024414743 scopus 로고
    • Oxygen dependent regulation of mammalian ribonucleotide reductase in vivo and possible significance for replicon initiation
    • Probst, H., H. Schiffer, V. Gekeler, and K. Scheffier. 1989. Oxygen dependent regulation of mammalian ribonucleotide reductase in vivo and possible significance for replicon initiation. Biochem. Biophys. Res. Commun. 163:334-340.
    • (1989) Biochem. Biophys. Res. Commun. , vol.163 , pp. 334-340
    • Probst, H.1    Schiffer, H.2    Gekeler, V.3    Scheffier, K.4
  • 44
    • 0025339557 scopus 로고
    • Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblasts
    • Reed, J. C., S. Haldar, C. M. Croce, and M. P. Cuddy. 1990. Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblasts. Mol. Cell. Biol. 10:4370-4374.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4370-4374
    • Reed, J.C.1    Haldar, S.2    Croce, C.M.3    Cuddy, M.P.4
  • 45
    • 0029753768 scopus 로고    scopus 로고
    • Genetic instability induced by the tumor microenvironment
    • Reynolds, T. Y., S. Rockwell, and P. M. Glazer. 1996. Genetic instability induced by the tumor microenvironment. Cancer Res. 56:5754-5757.
    • (1996) Cancer Res. , vol.56 , pp. 5754-5757
    • Reynolds, T.Y.1    Rockwell, S.2    Glazer, P.M.3
  • 46
    • 0026496272 scopus 로고
    • Reversible shutdown of replicon initiation by transient hypoxia in Ehrlich ascites cells. Dependence of initiation on short-lived protein
    • Riedinger, H. J., V. Gekeler, and H. Probst. 1992. Reversible shutdown of replicon initiation by transient hypoxia in Ehrlich ascites cells. Dependence of initiation on short-lived protein. Eur. J. Biochem. 210:389-398.
    • (1992) Eur. J. Biochem. , vol.210 , pp. 389-398
    • Riedinger, H.J.1    Gekeler, V.2    Probst, H.3
  • 47
    • 0033020644 scopus 로고    scopus 로고
    • Hypoxia blocks in vivo initiation of simian virus 40 replication at a stage preceding origin unwinding
    • Riedinger, H. J., M. van Betteraey, and H. Probst. 1999. Hypoxia blocks in vivo initiation of simian virus 40 replication at a stage preceding origin unwinding. J. Virol. 73:2243-2252.
    • (1999) J. Virol. , vol.73 , pp. 2243-2252
    • Riedinger, H.J.1    Van Betteraey, M.2    Probst, H.3
  • 48
    • 0032409943 scopus 로고    scopus 로고
    • Mechanisms of cell death in hypoxia/reoxygenation injury
    • Saikumar, P., Z. Dong, J. M. Weinberg, and M. A. Venkatachalam. 1998. Mechanisms of cell death in hypoxia/reoxygenation injury. Oncogene 17:3341-3349.
    • (1998) Oncogene , vol.17 , pp. 3341-3349
    • Saikumar, P.1    Dong, Z.2    Weinberg, J.M.3    Venkatachalam, M.A.4
  • 49
    • 0030726461 scopus 로고    scopus 로고
    • Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins
    • Samuelson, A. V., and S. W. Lowe. 1997. Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins. Proc. Natl. Acad. Sci. USA 94:12094-12099.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12094-12099
    • Samuelson, A.V.1    Lowe, S.W.2
  • 50
    • 0036481699 scopus 로고    scopus 로고
    • Adenoviral E1A: Everlasting tool, versatile applications, continuous contributions and new hypotheses
    • Sang, N., J. Caro, and A. Giordano. 2002. Adenoviral E1A: everlasting tool, versatile applications, continuous contributions and new hypotheses. Front. Biosci. 7:d407-d413.
    • (2002) Front. Biosci. , vol.7
    • Sang, N.1    Caro, J.2    Giordano, A.3
  • 52
    • 0031918244 scopus 로고    scopus 로고
    • Regulation of proliferation-survival decisions during tumor cell hypoxia
    • Schmaltz, C., P. H. Hardenbergh, A. Wells, and D. E. Fisher. 1998. Regulation of proliferation-survival decisions during tumor cell hypoxia. Mol. Cell. Biol. 18:2845-2854.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2845-2854
    • Schmaltz, C.1    Hardenbergh, P.H.2    Wells, A.3    Fisher, D.E.4
  • 53
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr, C. J., and J. M. Roberts. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 13:1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 56
    • 0037154738 scopus 로고    scopus 로고
    • Effect of p53 status on tumor response to antiangiogenic therapy
    • Yu, J. L., J. W. Rak, B. L. Coomber, D. J. Hicklin, and R. S. Kerbel. 2002. Effect of p53 status on tumor response to antiangiogenic therapy. Science 295:1526-1528.
    • (2002) Science , vol.295 , pp. 1526-1528
    • Yu, J.L.1    Rak, J.W.2    Coomber, B.L.3    Hicklin, D.J.4    Kerbel, R.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.