Double-sieving-defective aminoacyl-tRNA synthetase causes protein mistranslation and affects cellular physiology and development

Nature Communications

Volumn 5, Issue , 2014, Pages

  Lu, Jiongming ^a   Bergert, Martin ^a,b   Walther, Anita ^a,c   Suter, Beat ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE TRANSFER RNA LIGASE; TYROSINE; DROSOPHILA PROTEIN;

AMINO ACID; APOPTOSIS; ENZYME ACTIVITY; GENE EXPRESSION; GERM CELL; INSECT; MUTATION; NEUROLOGY; RNA; SIEVING;

ADULT; AMINOACYLATION; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; DROSOPHILA MELANOGASTER; ENDOPLASMIC RETICULUM STRESS; ENZYME SPECIFICITY; MOLECULAR RECOGNITION; NERVE CELL; NONHUMAN; ORGAN SIZE; PHOTORECEPTOR CELL; PROMOTER REGION; PROTEIN FOLDING; PROTEIN MISTRANSLATION; PROTEIN MODIFICATION; RNA INTERFERENCE; UNFOLDED PROTEIN RESPONSE; ANIMAL; CYTOLOGY; DEFICIENCY; ENZYMOLOGY; GENE INACTIVATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PROTEIN SYNTHESIS;

DROSOPHILA MELANOGASTER;

ANIMALS; CELL DEATH; CELL PROLIFERATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOPLASMIC RETICULUM STRESS; GENE KNOCKOUT TECHNIQUES; MUTATION; PHENYLALANINE-TRNA LIGASE; PROTEIN BIOSYNTHESIS;

EID: 84923250546     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6650     Document Type: Article

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