Severe oxidative stress induces protein mistranslation through impairment of an aminoacyl-tRNA synthetase editing site

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 9, 2010, Pages 4028-4033

  Ling, Jiqiang ^a   Söll, Dieter ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

AaRS; Quality control; ROS; Translational fidelity

Indexed keywords

AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; CYSTEINE; HEAT SHOCK PROTEIN; PROTEINASE; REACTIVE OXYGEN METABOLITE; SERINE;

ARTICLE; BACTERIAL GROWTH; CELL GROWTH; ESCHERICHIA COLI; GENETIC CODE; GENETICS; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SYNTHESIS; RNA EDITING; RNA TRANSLATION;

AMINO ACYL-TRNA SYNTHETASES; BETA-LACTAMASES; ESCHERICHIA COLI; OXIDATIVE STRESS; PROTEIN BIOSYNTHESIS; RNA EDITING;

ESCHERICHIA COLI;

EID: 77749239882     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1000315107     Document Type: Article

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