Mesenchymal progenitors aging highlights a mir-196 switch targeting HOXB7 as master regulator of proliferation and osteogenesis

Stem Cells

Volumn 33, Issue 3, 2015, Pages 939-950

  Candini, Olivia ^a   Spano, Carlotta ^a   Murgia, Alba ^a   Grisendi, Giulia ^a   Veronesi, Elena ^a   Piccinno, Maria Serena ^a   Ferracin, Manuela ^b   Negrini, Massimo ^b   Giacobbi, Francesca ^a   Bambi, Franco ^c   Horwitz, Edwin Mark ^d   Conte, Pierfranco ^e   Paolucci, Paolo ^a   Dominici, Massimo ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

^e UNIVERSITY OF PADOVA   (Italy)

Author keywords

Aging; Bone; Bone marrow stromal cells; Homeobox genes

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; HOX PROTEIN; KI 67 ANTIGEN; MICRORNA; MICRORNA 100; MICRORNA 196A; MICRORNA 196B; MICRORNA 337 5P; MICRORNA 376 B; MICRORNA 431; MICRORNA 543; MICRORNA 99A; PROTEIN HOXB7; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; HOXB7 PROTEIN, HUMAN; HOXB7 PROTEIN, MOUSE; MIRN196 MICRORNA, HUMAN; MIRN196 MICRORNA, MOUSE;

ADULT; AGE DISTRIBUTION; AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; BONE DEVELOPMENT; CELL GROWTH; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MESENCHYMAL STEM CELL; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN SECRETION; PROTEIN TARGETING; SENESCENCE; UPREGULATION; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

MUS;

ADULT; AGED; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICRORNAS; MIDDLE AGED; OSTEOGENESIS;

EID: 84923234003     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1897     Document Type: Article

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