The glucagon receptor antagonist BI-32169 constitutes a new class of lasso peptides

FEBS Letters

Volumn 584, Issue 4, 2010, Pages 785-789

  Knappe, Thomas A ^a   Linne, Uwe ^a   Xie, Xiulan ^a   Marahiel, Mohamed A ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Disulfide bond formation; Glucagon receptor antagonist; Lasso peptide; Mass fragmentation; NMR structure; Protein scaffold

Indexed keywords

BACTERIAL PROTEIN; BI 32169; GLUCAGON RECEPTOR ANTAGONIST; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CLASSIFICATION; MOLECULAR IMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; STREPTOMYCES; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; PROTEIN FOLDING; RECEPTORS, GLUCAGON; STREPTOMYCES; TANDEM MASS SPECTROMETRY;

STREPTOMYCES SP.;

EID: 77649270287     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.12.046     Document Type: Article

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