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Volumn 308, Issue 4, 2015, Pages R283-R293

Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats

Author keywords

Diet; GPR4; GPR41; Rumen epithelial cells; SCFA and pH; UT B expression

Indexed keywords

AMMONIA; CARBOHYDRATE; CARRIER PROTEIN; G PROTEIN COUPLED RECEPTOR 4; G PROTEIN COUPLED RECEPTOR 41; MESSENGER RNA; NITROGEN; RECEPTOR; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG; UREA TRANSPORTER B; AMMONIUM CHLORIDE; CARBOHYDRATE DIET; FATTY ACID; G PROTEIN COUPLED RECEPTOR; UREA; UREA TRANSPORTER;

EID: 84923186725     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00323.2014     Document Type: Article
Times cited : (47)

References (64)
  • 2
    • 24044476191 scopus 로고    scopus 로고
    • Modulation of electroneutral Na transport in sheep rumen epithelium by luminal ammonia
    • Abdoun K, Stumpff F, Wolf K, Martens H. Modulation of electroneutral Na transport in sheep rumen epithelium by luminal ammonia. Am J Physiol Gastrointest Liver Physiol 289: G508–G520, 2005.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289 , pp. G508-G520
    • Abdoun, K.1    Stumpff, F.2    Wolf, K.3    Martens, H.4
  • 3
    • 0142009960 scopus 로고    scopus 로고
    • + transport across isolated rumen epithelium of sheep is diet dependent
    • + transport across isolated rumen epithelium of sheep is diet dependent. Br J Nutr 90: 751–758, 2003.
    • (2003) Br J Nutr , vol.90 , pp. 751-758
    • Abdoun, K.1    Wolf, K.2    Arndt, G.3    Martens, H.4
  • 4
    • 78650179808 scopus 로고    scopus 로고
    • Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
    • Al-Lahham SH, Peppelenbosch MP, Roelofsen H, Vonk RJ, Venema K. Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. Biochim Biophys Acta 1801: 1175–1183, 2010.
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 1175-1183
    • Al-Lahham, S.H.1    Peppelenbosch, M.P.2    Roelofsen, H.3    Vonk, R.J.4    Venema, K.5
  • 5
    • 38949196757 scopus 로고    scopus 로고
    • Extracellular pH regulates bone cell function
    • Arnett TR. Extracellular pH regulates bone cell function. J Nutr 138: 415S–418S, 2008.
    • (2008) J Nutr , vol.138 , pp. 415S-418S
    • Arnett, T.R.1
  • 6
    • 0030201472 scopus 로고    scopus 로고
    • + in total ammonia absorption across the rumen epithelium of sheep (Ovis aries)
    • + in total ammonia absorption across the rumen epithelium of sheep (Ovis aries). Comp Biochem Physiol A Physiol 114: 305–310, 1996.
    • (1996) Comp Biochem Physiol a Physiol , vol.114 , pp. 305-310
    • Bödeker, D.1    Kemkowski, J.2
  • 7
    • 84904680800 scopus 로고    scopus 로고
    • Urea recycling contributes to nitrogen retention in calves fed milk replacer and low-protein solid feed
    • Berends H, van den Borne JJ, Rojen BA, van Baal J, Gerrits WJ. Urea recycling contributes to nitrogen retention in calves fed milk replacer and low-protein solid feed. J Nutr 144: 1043–1049, 2014.
    • (2014) J Nutr , vol.144 , pp. 1043-1049
    • Berends, H.1    Van Den Borne, J.J.2    Rojen, B.A.3    Van Baal, J.4    Gerrits, W.J.5
  • 8
    • 0025321505 scopus 로고
    • Energy contributions of volatile fatty acids from the gastrointestinal tract in various species
    • Bergman EN. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiol Rev 70: 567–590, 1990.
    • (1990) Physiol Rev , vol.70 , pp. 567-590
    • Bergman, E.N.1
  • 9
    • 0018813422 scopus 로고
    • Automated simultaneous determination of ammonia and total amino acids in ruminal fluid and in vitro media
    • Broderick GA, Kang JH. Automated simultaneous determination of ammonia and total amino acids in ruminal fluid and in vitro media. J Dairy Sci 63: 64–75, 1980.
    • (1980) J Dairy Sci , vol.63 , pp. 64-75
    • Broderick, G.A.1    Kang, J.H.2
  • 11
    • 81155128295 scopus 로고    scopus 로고
    • Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway
    • Chen A, Dong L, Leffler NR, Asch AS, Witte ON, Yang LV. Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway. PLos One 6: e27586, 2011.
    • (2011) Plos One , vol.6
    • Chen, A.1    Dong, L.2    Leffler, N.R.3    Asch, A.S.4    Witte, O.N.5    Yang, L.V.6
  • 12
    • 34248663955 scopus 로고    scopus 로고
    • The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: Twentysomething years on
    • Chomczynski P, Sacchi N. The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twentysomething years on. Nat Protoc 1: 581–585, 2006.
    • (2006) Nat Protoc , vol.1 , pp. 581-585
    • Chomczynski, P.1    Sacchi, N.2
  • 13
    • 84878973500 scopus 로고    scopus 로고
    • Intracellular and extracellular pH and Ca are bound to control mitosis in the early sea urchin embryo via ERK and MPF activities
    • Ciapa B, Philippe L. Intracellular and extracellular pH and Ca are bound to control mitosis in the early sea urchin embryo via ERK and MPF activities. PLos One 8: e66113, 2013.
    • (2013) Plos One , vol.8
    • Ciapa, B.1    Philippe, L.2
  • 14
    • 0022709956 scopus 로고
    • Forestomach epithelial receptor activation by rumen fluids from sheep given intraruminal infusions of volatile fatty acids
    • Crichlow EC, Leek BF. Forestomach epithelial receptor activation by rumen fluids from sheep given intraruminal infusions of volatile fatty acids. Am J Vet Res 47: 1015–1018, 1986.
    • (1986) Am J Vet Res , vol.47 , pp. 1015-1018
    • Crichlow, E.C.1    Leek, B.F.2
  • 15
    • 84883139076 scopus 로고    scopus 로고
    • The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
    • den Besten G, van Eunen K, Groen AK, Venema K, Reijngoud DJ, Bakker BM. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res 54: 2325–2340, 2013.
    • (2013) J Lipid Res , vol.54 , pp. 2325-2340
    • Den Besten, G.1    Van Eunen, K.2    Groen, A.K.3    Venema, K.4    Reijngoud, D.J.5    Bakker, B.M.6
  • 19
    • 84883052435 scopus 로고    scopus 로고
    • Effects of ammonia and urea in vitro on mRNA of candidate bovine endometrial genes
    • Gunaretnam I, Pretheeban T, Rajamahendran R. Effects of ammonia and urea in vitro on mRNA of candidate bovine endometrial genes. Anim Reprod Sci 141: 42–51, 2013.
    • (2013) Anim Reprod Sci , vol.141 , pp. 42-51
    • Gunaretnam, I.1    Pretheeban, T.2    Rajamahendran, R.3
  • 21
    • 0019073032 scopus 로고
    • Aspects of urea metabolism in ruminants with reference to the goat
    • Harmeyer J, Martens H. Aspects of urea metabolism in ruminants with reference to the goat. J Dairy Sci 63: 1707–1728, 1980.
    • (1980) J Dairy Sci , vol.63 , pp. 1707-1728
    • Harmeyer, J.1    Martens, H.2
  • 22
    • 84923202897 scopus 로고    scopus 로고
    • Chronic Kidney Disease and Renal Transplantation
    • Hassan Y. Chronic Kidney Disease and Renal Transplantation. Rijeka, Croatia: InTech, 2012.
    • (2012) Rijeka, Croatia: Intech
    • Hassan, Y.1
  • 23
    • 84864110501 scopus 로고    scopus 로고
    • Moderate extracellular acidification inhibits capsaicin-induced cell death through regulating calcium mobilization, NF-kappaB translocation and ROS production in synoviocytes
    • Hu F, Yang S, Zhao D, Zhu S, Wang Y, Li J. Moderate extracellular acidification inhibits capsaicin-induced cell death through regulating calcium mobilization, NF-kappaB translocation and ROS production in synoviocytes. Biochem Biophys Res Commun 424: 196–200, 2012.
    • (2012) Biochem Biophys Res Commun , vol.424 , pp. 196-200
    • Hu, F.1    Yang, S.2    Zhao, D.3    Zhu, S.4    Wang, Y.5    Li, J.6
  • 25
    • 0027479225 scopus 로고
    • LeBoeuf RA. Induction of protein phosphorylation, protein synthesis, immediateearly- gene expression and cellular proliferation by intracellular pH modulation. Implications for the role of hydrogen ions in signal transduction
    • Isfort RJ, Cody DB, Asquith TN, Ridder GM, Stuard SB, LeBoeuf RA. Induction of protein phosphorylation, protein synthesis, immediateearly- gene expression and cellular proliferation by intracellular pH modulation. Implications for the role of hydrogen ions in signal transduction. Eur J Biochem 213: 349–357, 1993.
    • (1993) Eur J Biochem , vol.213 , pp. 349-357
    • Isfort, R.J.1    Cody, D.B.2    Asquith, T.N.3    Ridder, G.M.4    Stuard, S.B.5
  • 26
    • 84880620577 scopus 로고    scopus 로고
    • Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice
    • Kim MH, Kang SG, Park JH, Yanagisawa M, Kim CH. Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice. Gastroenterology 145: 396–406, e391–e310, 2013.
    • (2013) Gastroenterology , vol.145 , pp. 396-406
    • Kim, M.H.1    Kang, S.G.2    Park, J.H.3    Yanagisawa, M.4    Kim, C.H.5
  • 27
    • 77649178167 scopus 로고    scopus 로고
    • Effects of partial ruminal defaunation on urea-nitrogen recycling, nitrogen metabolism, and microbial nitrogen supply in growing lambs fed low or high dietary crude protein concentrations
    • Kiran D, Mutsvangwa T. Effects of partial ruminal defaunation on urea-nitrogen recycling, nitrogen metabolism, and microbial nitrogen supply in growing lambs fed low or high dietary crude protein concentrations. J Anim Sci 88: 1034–1047, 2010.
    • (2010) J Anim Sci , vol.88 , pp. 1034-1047
    • Kiran, D.1    Mutsvangwa, T.2
  • 28
    • 33747624390 scopus 로고    scopus 로고
    • Monocarboxylate transporter 1 (MCT1) mediates transport of short-chain fatty acids in bovine caecum
    • Kirat D, Kato S. Monocarboxylate transporter 1 (MCT1) mediates transport of short-chain fatty acids in bovine caecum. Exp Physiol 91: 835–844, 2006.
    • (2006) Exp Physiol , vol.91 , pp. 835-844
    • Kirat, D.1    Kato, S.2
  • 29
    • 0036189204 scopus 로고    scopus 로고
    • Acidosis mediates the upregulation of UT-A protein in livers from uremic rats
    • Klein JD, Rouillard P, Roberts BR, Sands JM. Acidosis mediates the upregulation of UT-A protein in livers from uremic rats. J Am Soc Nephrol 13: 581–587, 2002.
    • (2002) J am Soc Nephrol , vol.13 , pp. 581-587
    • Klein, J.D.1    Rouillard, P.2    Roberts, B.R.3    Sands, J.M.4
  • 31
    • 84901327600 scopus 로고    scopus 로고
    • Identification of the porcine G proteincoupled receptor 41 and 43 genes and their expression pattern in different tissues and development stages
    • Li G, Su H, Zhou Z, Yao W. Identification of the porcine G proteincoupled receptor 41 and 43 genes and their expression pattern in different tissues and development stages. PLos One 9: e97342, 2014.
    • (2014) Plos One , vol.9
    • Li, G.1    Su, H.2    Zhou, Z.3    Yao, W.4
  • 33
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2[-delta delta C(T)] method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2[-delta delta C(T)] method. Methods 25: 402–408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 63849322139 scopus 로고    scopus 로고
    • Effect of protein supplementation on expression and distribution of urea transporter-B in lambs fed low-quality forage
    • Ludden PA, Stohrer RM, Austin KJ, Atkinson RL, Belden EL, Harlow HJ. Effect of protein supplementation on expression and distribution of urea transporter-B in lambs fed low-quality forage. J Anim Sci 87: 1354–1365, 2009.
    • (2009) J Anim Sci , vol.87 , pp. 1354-1365
    • Ludden, P.A.1    Stohrer, R.M.2    Austin, K.J.3    Atkinson, R.L.4    Belden, E.L.5    Harlow, H.J.6
  • 36
    • 80054111810 scopus 로고    scopus 로고
    • Fermentation in the human large intestine: Its physiologic consequences and the potential contribution of prebiotics
    • Macfarlane GT, Macfarlane S. Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics. J Clin Gastroenterol 45, Suppl: S120–S127, 2011.
    • (2011) J Clin Gastroenterol 45, Suppl , pp. S120-S127
    • Macfarlane, G.T.1    Macfarlane, S.2
  • 37
    • 62149125733 scopus 로고
    • The effect of pH on growth, protein synthesis, and lipid-rich particles of cultured mammalian cells
    • Mackenzie CG, Mackenzie JB, Beck P. The effect of pH on growth, protein synthesis, and lipid-rich particles of cultured mammalian cells. J Biophys Biochem Cytol 9: 141–156, 1961.
    • (1961) J Biophys Biochem Cytol , vol.9 , pp. 141-156
    • Mackenzie, C.G.1    Mackenzie, J.B.2    Beck, P.3
  • 38
    • 84888060535 scopus 로고    scopus 로고
    • Increased papillae growth and enhanced short-chain fatty acid absorption in the rumen of goats are associated with transient increases in cyclin D1 expression after ruminal butyrate infusion
    • Malhi M, Gui H, Yao L, Aschenbach JR, Gabel G, Shen Z. Increased papillae growth and enhanced short-chain fatty acid absorption in the rumen of goats are associated with transient increases in cyclin D1 expression after ruminal butyrate infusion. J Dairy Sci 96: 7603–7616, 2013.
    • (2013) J Dairy Sci , vol.96 , pp. 7603-7616
    • Malhi, M.1    Gui, H.2    Yao, L.3    Aschenbach, J.R.4    Gabel, G.5    Shen, Z.6
  • 39
    • 2342593921 scopus 로고    scopus 로고
    • Effect of nitrogen intake on nitrogen recycling and urea transporter abundance in lambs
    • Marini JC, Klein JD, Sands JM, Van Amburgh ME. Effect of nitrogen intake on nitrogen recycling and urea transporter abundance in lambs. J Anim Sci 82: 1157–1164, 2004.
    • (2004) J Anim Sci , vol.82 , pp. 1157-1164
    • Marini, J.C.1    Klein, J.D.2    Sands, J.M.3    Van Amburgh, M.E.4
  • 40
    • 0038204410 scopus 로고    scopus 로고
    • Nitrogen metabolism and recycling in Holstein heifers
    • Marini JC, Van Amburgh ME. Nitrogen metabolism and recycling in Holstein heifers. J Anim Sci 81: 545–552, 2003.
    • (2003) J Anim Sci , vol.81 , pp. 545-552
    • Marini, J.C.1    Van Amburgh, M.E.2
  • 41
    • 77957240311 scopus 로고    scopus 로고
    • Dietary nitrogen reduction enhances urea transport across goat rumen epithelium
    • Muscher AS, Schroder B, Breves G, Huber K. Dietary nitrogen reduction enhances urea transport across goat rumen epithelium. J Anim Sci 88: 3390–3398, 2010.
    • (2010) J Anim Sci , vol.88 , pp. 3390-3398
    • Muscher, A.S.1    Schroder, B.2    Breves, G.3    Huber, K.4
  • 42
    • 59849113547 scopus 로고    scopus 로고
    • Microbes in gastrointestinal health and disease
    • Neish AS. Microbes in gastrointestinal health and disease. Gastroenterology 136: 65–80, 2009.
    • (2009) Gastroenterology , vol.136 , pp. 65-80
    • Neish, A.S.1
  • 43
    • 0037453280 scopus 로고    scopus 로고
    • Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by shortchain fatty acids
    • Nilsson NE, Kotarsky K, Owman C, Olde B. Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by shortchain fatty acids. Biochem Biophys Res Commun 303: 1047–1052, 2003.
    • (2003) Biochem Biophys Res Commun , vol.303 , pp. 1047-1052
    • Nilsson, N.E.1    Kotarsky, K.2    Owman, C.3    Olde, B.4
  • 45
    • 33745686063 scopus 로고    scopus 로고
    • Lysophosphatidylcholine impairs endothelial barrier function through the G proteincoupled receptor GPR4
    • Qiao J, Huang F, Naikawadi RP, Kim KS, Said T, Lum H. Lysophosphatidylcholine impairs endothelial barrier function through the G proteincoupled receptor GPR4. Am J Physiol Lung Cell Mol Physiol 291: L91–L101, 2006.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , pp. LL91-L101
    • Qiao, J.1    Huang, F.2    Naikawadi, R.P.3    Kim, K.S.4    Said, T.5    Lum, H.6
  • 46
    • 79955118967 scopus 로고    scopus 로고
    • Short communication: Effects of dietary nitrogen concentration on messenger RNA expression and protein abundance of urea transporter-B and aquaporins in ruminal papillae from lactating Holstein cows
    • Røjen BA, Poulsen SB, Theil PK, Fenton RA, Kristensen NB. Short communication: Effects of dietary nitrogen concentration on messenger RNA expression and protein abundance of urea transporter-B and aquaporins in ruminal papillae from lactating Holstein cows. J Dairy Sci 94: 2587–2591, 2011.
    • (2011) J Dairy Sci , vol.94 , pp. 2587-2591
    • Røjen, B.A.1    Poulsen, S.B.2    Theil, P.K.3    Fenton, R.A.4    Kristensen, N.B.5
  • 47
    • 0033826848 scopus 로고    scopus 로고
    • Dietary regulation of intestinal gene expression
    • Sanderson IR, Naik S. Dietary regulation of intestinal gene expression. Annu Rev Nutr 20: 311–338, 2000.
    • (2000) Annu Rev Nutr , vol.20 , pp. 311-338
    • Sanderson, I.R.1    Naik, S.2
  • 48
    • 84875197267 scopus 로고    scopus 로고
    • The urea transporter family (SLC14): Physiological, pathological and structural aspects
    • Shayakul C, Clemencon B, Hediger MA. The urea transporter family (SLC14): physiological, pathological and structural aspects. Mol Aspects Med 34: 313–322, 2013.
    • (2013) Mol Aspects Med , vol.34 , pp. 313-322
    • Shayakul, C.1    Clemencon, B.2    Hediger, M.A.3
  • 50
    • 84882613780 scopus 로고    scopus 로고
    • Expression of urea transporters is affected by dietary nitrogen restriction in goat kidney
    • Starke S, Muscher AS, Hirschhausen N, Pfeffer E, Breves G, Huber K. Expression of urea transporters is affected by dietary nitrogen restriction in goat kidney. J Anim Sci 90: 3889–3897, 2012.
    • (2012) J Anim Sci , vol.90 , pp. 3889-3897
    • Starke, S.1    Muscher, A.S.2    Hirschhausen, N.3    Pfeffer, E.4    Breves, G.5    Huber, K.6
  • 51
    • 79955756631 scopus 로고    scopus 로고
    • Rumen epithelial adaptation to high-grain diets involves the coordinated regulation of genes involved in cholesterol homeostasis
    • Steele MA, Vandervoort G, AlZahal O, Hook SE, Matthews JC, McBride BW. Rumen epithelial adaptation to high-grain diets involves the coordinated regulation of genes involved in cholesterol homeostasis. Physiol Genomics 43: 308–316, 2011.
    • (2011) Physiol Genomics , vol.43 , pp. 308-316
    • Steele, M.A.1    Vandervoort, G.2    Alzahal, O.3    Hook, S.E.4    Matthews, J.C.5    Mc bride, B.W.6
  • 52
    • 81355124793 scopus 로고    scopus 로고
    • The emerging physiological roles of the SLC14A family of urea transporters
    • Stewart G. The emerging physiological roles of the SLC14A family of urea transporters. Br J Pharmacol 164: 1780–1792, 2011.
    • (2011) Br J Pharmacol , vol.164 , pp. 1780-1792
    • Stewart, G.1
  • 56
    • 24344474845 scopus 로고    scopus 로고
    • Proton-sensing and lysolipidsensitive G-protein-coupled receptors: A novel type of multi-functional receptors
    • Tomura H, Mogi C, Sato K, Okajima F. Proton-sensing and lysolipidsensitive G-protein-coupled receptors: a novel type of multi-functional receptors. Cell Signal 17: 1466–1476, 2005.
    • (2005) Cell Signal , vol.17 , pp. 1466-1476
    • Tomura, H.1    Mogi, C.2    Sato, K.3    Okajima, F.4
  • 58
  • 59
    • 67649211163 scopus 로고    scopus 로고
    • Identification and characterization of the bovine G protein-coupled receptor GPR41 and GPR43 genes
    • Wang A, Gu Z, Heid B, Akers RM, Jiang H. Identification and characterization of the bovine G protein-coupled receptor GPR41 and GPR43 genes. J Dairy Sci 92: 2696–2705, 2009.
    • (2009) J Dairy Sci , vol.92 , pp. 2696-2705
    • Wang, A.1    Gu, Z.2    Heid, B.3    Akers, R.M.4    Jiang, H.5
  • 61
    • 0015123799 scopus 로고
    • Manual and automated methods for urea nitrogen measurement in whole serum
    • Wybenga DR, Di Giorgio J, Pileggi VJ. Manual and automated methods for urea nitrogen measurement in whole serum. Clin Chem 17: 891–895, 1971.
    • (1971) Clin Chem , vol.17 , pp. 891-895
    • Wybenga, D.R.1    Di Giorgio, J.2    Pileggi, V.J.3
  • 62
    • 84855388316 scopus 로고    scopus 로고
    • An energy-rich diet enhances expression of Na(+)/H(+) exchanger isoform 1 and 3 messenger RNA in rumen epithelium of goat
    • Yang W, Shen Z, Martens H. An energy-rich diet enhances expression of Na(+)/H(+) exchanger isoform 1 and 3 messenger RNA in rumen epithelium of goat. J Anim Sci 90: 307–317, 2012.
    • (2012) J Anim Sci , vol.90 , pp. 307-317
    • Yang, W.1    Shen, Z.2    Martens, H.3
  • 63
    • 84897397009 scopus 로고    scopus 로고
    • Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in novel small ubiquitin-like modifier transgenic mice Putative protective proteins/pathways
    • Yang W, Sheng H, Thompson JW, Zhao S, Wang L, Miao P, Liu X, Moseley MA, Paschen W. Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in novel small ubiquitin-like modifier transgenic mice putative protective proteins/pathways. Stroke 45: 1115–1122, 2014.
    • (2014) Stroke , vol.45 , pp. 1115-1122
    • Yang, W.1    Sheng, H.2    Thompson, J.W.3    Zhao, S.4    Wang, L.5    Miao, P.6    Liu, X.7    Moseley, M.A.8    Paschen, W.9
  • 64
    • 59849087617 scopus 로고    scopus 로고
    • Short-chain fatty acid signaling pathways in bovine mammary epithelial cells
    • Yonezawa T, Haga S, Kobayashi Y, Katoh K, Obara Y. Short-chain fatty acid signaling pathways in bovine mammary epithelial cells. Regul Pept 153: 30–36, 2009.
    • (2009) Regul Pept , vol.153 , pp. 30-36
    • Yonezawa, T.1    Haga, S.2    Kobayashi, Y.3    Katoh, K.4    Obara, Y.5


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