Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression

Journal of Investigative Dermatology

Volumn 132, Issue 6, 2012, Pages 1561-1572

  Grether Beck, Susanne ^a   Felsner, Ingo ^a   Brenden, Heidi ^a   Kohne, Zippora ^a   Majora, Marc ^a   Marini, Alessandra ^a   Jaenicke, Thomas ^a   Rodriguez Martin, Marina ^b   Trullas, Carles ^c   Hupe, Melanie ^d   Elias, Peter M ^d   Krutmann, Jean ^a  

^a IUF LEIBNIZ RESEARCH INSTITUTE FOR ENVIRONMENTAL MEDICINE   (Germany)

^b HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

^c ISDIN   (Spain)

^d SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN 3; AQUAPORIN 7; AQUAPORIN 9; BETA DEFENSIN 2; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; FILAGGRIN; INVOLUCRIN; LORICRIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TRANSGLUTAMINASE 1; UNCLASSIFIED DRUG; UREA; UREA TRANSPORTER A1; UREA TRANSPORTER A2;

ANIMAL MODEL; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VOLUNTEER;

EID: 84861194891     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.42     Document Type: Article

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