Expression of urea transporters is affected by dietary nitrogen restriction in goat kidney

Journal of Animal Science

Volumn 90, Issue 11, 2012, Pages 3889-3897

  Starke, S ^a   Muscher, A S ^a   Hirschhausen, N ^b   Pfeffer, E ^c   Breves, G ^a   Huber, K ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

Dietary nitrogen; Goats; Kidney; Urea excretion; Urea transporter

Indexed keywords

CARRIER PROTEIN; NITROGEN; UREA TRANSPORTER;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; DIET; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GOAT; KIDNEY; MALE; METABOLISM; MOLECULAR GENETICS; NORTHERN BLOTTING; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMAL FEED; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DIET; GENE EXPRESSION REGULATION; GOATS; KIDNEY; MALE; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; NITROGEN;

EID: 84882613780     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2011-4262     Document Type: Article

References (24)

1. Artagaveytia, N., J. M. Elalouf, C. de Rouffignac, R. Boivin, and A. Cirio. 2005. Expression of urea transporter (UT-A) mRNA in papilla and pelvic epithelium of kidney in normal and low protein fed sheep. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 140:279-285.
2. Bagnasco, S. M. 2005. Role and regulation of urea transporters. Pfl ugers Arch.-Eur. J. Physiol. 450:217-226.
3. Chen, G., O. Frohlich, Y. Yang, J. D. Klein, and J.M. Sands. 2006. Loss of N-linked glycosylation reduces urea transporter UT-A1 response to vasopressin. J. Biol. Chem. 281:27436-27442.
4. Doran, J. J., J. D. Klein, Y. H. Kim, T. D. Smith, S. D. Kozlowski, R.B. Gunn, and J.M. Sands. 2006. Tissue distribution of UT-A and UT-B mRNA and protein in rat. Am. J. Physiol. Regul. Integr. Comp. Physiol. 290:R1446-R1459.
5. Huber, K., U. Roesler, A. Muscher, K. Hansen, I. Widiyono, E. Pfeffer, and G. Breves. 2003. Ontogenesis of epithelial phosphate transport systems in goats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284:R413-R421.
6. Huber, K., C. Walter, B. Schroeder, and G. Breves. 2002. Phosphate transport in the duodenum and jejunum of goats and its adaptation by dietary phosphate and calcium. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283:R296-302.
7. Inoue, H., S. D. Kozlowski, J. D. Klein, J. L. Bailey, J. M. Sands, and S. M. Bagnasco. 2005. Regulated expression of renal and intetinal UT-B urea transporter in response to varying urea load. Am. J. Physiol. Renal. Physiol. 289: F451-F458.
8. Jung, K., C. Wesslau, F. Priem, G. Schreiber, and A. Zubek. 1987. Specific creatinine determination in laboratory animals using the new enzymatic test kit "Creatinine-pap". J. Clin. Chem. Clin. Biochem. 25:357-361.
9. Kamphues, J., M. Coenen, E. Kienzle, J. Pallauf, O. Simon, and J. Zentek. 2004. Supplemente zu Vorlesungen und Übungen in der Tierernährung. p. 201 in Ernährung verschiedener Spezies, Rinder. M. & H. Schaper GmbH & Co. KG, Alfeld (Leine), Germany.
10. Kristensen, N. B., A. C. Storm, and M. Larsen. 2010. Effect of dietary nitrogen content and intravenous urea infusion on ruminal portaldrained visceral extraction of arterial urea in lactating Holstein cows. J. Dairy Sci. 93:2670-2683.
11. Lucien, N., P. Bruneval, F. Lasbennes, M.-F. Belair, C. Mandet, J.-P. Cartron, P. Bailly, and M.-M. Trinh-Trang-Tan. 2005. UT-B1 urea transporter is expressed along the urinary and gastrointestinal tracts of the mouse. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288:R1046-R1056.
12. Lucien, N., F. Sidoux-Walter, B. Olives, J. Moulds, P. Y. Le Pennec, J. P. Cartron, and P. Bailly. 1998. Characterization of the gene encoding the human Kidd blood group/urea transporter protein. Evidence for the splice site mutations in Jknull individuals. J. Biol. Chem. 273:12973-12980.
13. Ludden, P. A., R. M. Stohrer, K. J. Austin, R. L. Atkinson, E. L. Belden and H. J. Harlow. 2009. Effect of protein supplementation on expression and distribution of urea transporter-B in lambs fed lowquality forage. J. Anim. Sci. 87:1354-1365.
14. Marini, J. C., J. D. Klein, J. M. Sands, and M. E. Van Amburgh. 2004. Effect of nitrogen intake on nitrogen recycling and urea transporter abundance in lambs. J. Anim. Sci. 82:1157-1164.
15. Muscher, A., J. Hattendorf, E. Pfeffer, G. Breves, and K. Huber. 2008. Hormonal regulation of phosphate homeostasis in goats during transition to rumination. J. Comp. Physiol. B. 178:585-596.
16. Muscher, A., B. Schröder, G. Breves, and K. Huber. 2010. Dietary nitrogen reduction enhances urea transport across goat rumen epithelium. J. Anim. Sci. 88:3390-3398.
17. Naumann, C., and R. Bassler. 1976. Verband Deutscher Landwirtschaftlicher Untersuchungs-und Forschungsanstalten. Methodenbuch Band III. Die chemische Untersuchung von Futtermitteln. Mit Ergänzungslieferungen 1983, 1988, 1993, 1997. VDLUFA-Verlag, Darmstadt, Germany.
18. NRC 1981. Nutrient requirements of domestic animals. No. 15. Nutrient requirements of goats. Natl. Acad. Press, Washington, DC.
19. Pfeffer, E., H. Specker, S. Bornemann, A. Holthausen, and M. Rodehutscord. 2009. Kinetics of endogenous urea in lactating goats and cows fed diets varying in their crude protein concentrations. Arch. Anim. Nutr. 63:230-242
20. Reynolds, C. K., and N. B. Kristensen. 2007. Nitrogen recycling through the gut and the nitrogen economy of ruminants: An asynchronous symbiosis. J. Anim. Sci. 86:E293-E305.
21. Rojen, B. A., P. K. Theil, and N. B. Kristensen. 2011. Effects of nitrogen supply on inter-organ fl uxes of urea-N and renal urea-N kinetics in lactating Holstein cows. J. Dairy Sci. 94:2532-2544.
22. Smith, C. P. 2009. Mammalian urea transporters. Exp. Physiol. 94:180-185.
23. Tebot, I., S. Faix, M. Szanyiova, A. Cirio, and L. Leng. 1998. Micropuncture study on urea movements in the kidney cortical tubules of low protein fed sheep. Vet. Res. 29:99-105.
24. Trinh-Trang-Tan, M. M., F. Lasbennes, P. Gane, N. Roudier, P. Ripoche, J. P. Cartron, and P. Bailly. 2002. UT-B1 proteins in rat: Tissue distribution and regulation by antidiuretic hormone in kidney. Am. J. Physiol. Renal Physiol. 283:F912-F922.