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Volumn 5, Issue 2, 2015, Pages

Multiscale cartilage biomechanics: Technical challenges in realizing a high-throughput modelling and simulation workflow

Author keywords

Cartilage; Chondrocyte; Extracellular; Finite element analysis; Pericellular; Post processing

Indexed keywords


EID: 84923166026     PISSN: 20428898     EISSN: 20428901     Source Type: Journal    
DOI: 10.1098/rsfs.2014.0081     Document Type: Article
Times cited : (24)

References (59)
  • 1
    • 84868368410 scopus 로고    scopus 로고
    • Multiscale mechanics of articular cartilage: Potentials and challenges of coupling musculoskeletal, joint, and microscale computational models
    • Halloran JP, Sibole S, van Donkelaar CC, van Turnhout MC, Oomens CWJ, Weiss JA, Guilak F, Erdemir A. 2012 Multiscale mechanics of articular cartilage: potentials and challenges of coupling musculoskeletal, joint, and microscale computational models. Ann. Biomed. Eng. 40, 2456-2474.(doi:10.1007/s10439-012-0598-0)
    • (2012) Ann. Biomed. Eng , vol.40 , pp. 2456-2474
    • Halloran, J.P.1    Sibole, S.2    Van Donkelaar, C.C.3    Van Turnhout, M.C.4    Oomens, C.5    Weiss, J.A.6    Guilak, F.7    Erdemir, A.8
  • 2
    • 0024382294 scopus 로고
    • Structure and biology of cartilage and bone matrix noncollagenous macromolecules
    • Heinega°rd D, Oldberg A
    • Heinega°rd D, Oldberg A. 1989 Structure and biology of cartilage and bone matrix noncollagenous macromolecules. FASEB J. 3, 2042-2051.
    • (1989) FASEB J , vol.3 , pp. 2042-2051
  • 3
    • 33947675353 scopus 로고    scopus 로고
    • A numerical study to determine pericellular matrix modulus and evaluate its effects on the micromechanical environment of chondrocytes
    • Michalek AJ, Iatridis JC. 2007 A numerical study to determine pericellular matrix modulus and evaluate its effects on the micromechanical environment of chondrocytes. J. Biomech. 40, 1405-1409.(doi:10.1016/j.jbiomech.2006.05.025)
    • (2007) J. Biomech , vol.40 , pp. 1405-1409
    • Michalek, A.J.1    Iatridis, J.C.2
  • 4
    • 33646875960 scopus 로고    scopus 로고
    • Effect of compressive strain on cell viability in statically loaded articular cartilage
    • Torzilli PA, Deng X-H, Ramcharan M. 2006 Effect of compressive strain on cell viability in statically loaded articular cartilage. Biomech. Model. Mechanobiol. 5, 123-132.(doi:10.1007/s10237-006-0030-5)
    • (2006) Biomech. Model. Mechanobiol , vol.5 , pp. 123-132
    • Torzilli, P.A.1    Deng, X.-H.2    Ramcharan, M.3
  • 5
    • 0034578147 scopus 로고    scopus 로고
    • Cartilage tissue remodeling in response to mechanical forces
    • Grodzinsky AJ, Levenston ME, Jin M, Frank EH. 2000 Cartilage tissue remodeling in response to mechanical forces. Annu. Rev. Biomed. Eng. 2, 691-713.(doi:10.1146/annurev.bioeng.2.1.691)
    • (2000) Annu. Rev. Biomed. Eng , vol.2 , pp. 691-713
    • Grodzinsky, A.J.1    Levenston, M.E.2    Jin, M.3    Frank, E.H.4
  • 6
    • 28344446498 scopus 로고    scopus 로고
    • Pathomechanisms of cartilage destruction by mechanical injury
    • Kurz B, Lemke AK, Fay J, Pufe T, Grodzinsky AJ, Schünke M. 2005 Pathomechanisms of cartilage destruction by mechanical injury. Ann. Anat. 187, 473-485.(doi:10.1016/j.aanat.2005.07.003)
    • (2005) Ann. Anat , vol.187 , pp. 473-485
    • Kurz, B.1    Lemke, A.K.2    Fay, J.3    Pufe, T.4    Grodzinsky, A.J.5    Schünke, M.6
  • 8
    • 5444264829 scopus 로고    scopus 로고
    • Chondrocyte senescence, joint loading and osteoarthritis
    • Martin JA, Brown TD, Heiner AD, Buckwalter JA. 2004 Chondrocyte senescence, joint loading and osteoarthritis. Clin. Orthop. S96-S103.(doi:10.1097/01.blo.0000143818.74887.b1)
    • (2004) Clin. Orthop , pp. SS96-S103
    • Martin, J.A.1    Brown, T.D.2    Heiner, A.D.3    Buckwalter, J.A.4
  • 9
    • 38149052992 scopus 로고    scopus 로고
    • Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. II
    • Lawrence RC et al. 2008 Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. II. Arthritis Rheum. 58, 26-35.(doi:10.1002/art.23176)
    • (2008) Arthritis Rheum , vol.58 , pp. 26-35
    • Lawrence, R.C.1
  • 10
    • 70349467887 scopus 로고    scopus 로고
    • Confocal microscopy indentation system for studying in situ chondrocyte mechanics
    • Han S-K, Colarusso P, Herzog W. 2009 Confocal microscopy indentation system for studying in situ chondrocyte mechanics. Med. Eng. Phys. 31, 1038-1042.(doi:10.1016/j.medengphy.2009.05.013)
    • (2009) Med. Eng. Phys , vol.31 , pp. 1038-1042
    • Han, S.-K.1    Colarusso, P.2    Herzog, W.3
  • 11
    • 79952037888 scopus 로고    scopus 로고
    • A novel method for determining articular cartilage chondrocyte mechanics in vivo
    • Abusara Z, Seerattan R, Leumann A, Thompson R, Herzog W. 2011 A novel method for determining articular cartilage chondrocyte mechanics in vivo. J. Biomech. 44, 930-934.(doi:10.1016/j.jbiomech.2010.11.031)
    • (2011) J. Biomech , vol.44 , pp. 930-934
    • Abusara, Z.1    Seerattan, R.2    Leumann, A.3    Thompson, R.4    Herzog, W.5
  • 12
    • 84894875987 scopus 로고    scopus 로고
    • Extracellular matrix integrity affects the mechanical behaviour of in situ chondrocytes under compression
    • Moo EK, Han SK, Federico S, Sibole SC, Jinha A, Abu Osman NA, Pingguan-Murphy B, Herzog W. 2014 Extracellular matrix integrity affects the mechanical behaviour of in situ chondrocytes under compression. J. Biomech. 47, 1004-1013.(doi:10.1016/j.jbiomech.2014.01.003)
    • (2014) J. Biomech , vol.47 , pp. 1004-1013
    • Moo, E.K.1    Han, S.K.2    Federico, S.3    Sibole, S.C.4    Jinha, A.5    Abu Osman, N.A.6    Pingguan-Murphy, B.7    Herzog, W.8
  • 13
    • 0035157124 scopus 로고    scopus 로고
    • Age-related changes in the morphology and deformational behavior of knee joint cartilage
    • Hudelmaier M, Glaser C, Hohe J, Englmeier KH, Reiser M, Putz R, Eckstein F. 2001 Age-related changes in the morphology and deformational behavior of knee joint cartilage. Arthritis Rheum. 44, 2556-2561.(doi:10.1002/1529-0131(200111)44:11,2556::AID-ART436.3.0.CO;2-U)
    • (2001) Arthritis Rheum , vol.44 , pp. 2556-2561
    • Hudelmaier, M.1    Glaser, C.2    Hohe, J.3    Englmeier, K.H.4    Reiser, M.5    Putz, R.6    Eckstein, F.7
  • 14
    • 84872600050 scopus 로고    scopus 로고
    • Depthdependent anisotropy of the micromechanical properties of the extracellular and pericellular matrices of articular cartilage evaluated via atomic force microscopy
    • McLeod MA, Wilusz RE, Guilak F. 2013 Depthdependent anisotropy of the micromechanical properties of the extracellular and pericellular matrices of articular cartilage evaluated via atomic force microscopy. J. Biomech. 46, 586-592.(doi:10.1016/j.jbiomech.2012.09.003)
    • (2013) J. Biomech , vol.46 , pp. 586-592
    • McLeod, M.A.1    Wilusz, R.E.2    Guilak, F.3
  • 15
    • 84872792659 scopus 로고    scopus 로고
    • Heterogeneity of tibial plateau cartilage in response to a physiological compressive strain rate
    • Deneweth JM, Newman KE, Sylvia SM, McLean SG, Arruda EM. 2013 Heterogeneity of tibial plateau cartilage in response to a physiological compressive strain rate. J. Orthop. Res. 31, 370-375.(doi:10.1002/jor.22226)
    • (2013) J. Orthop. Res , vol.31 , pp. 370-375
    • Deneweth, J.M.1    Newman, K.E.2    Sylvia, S.M.3    McLean, S.G.4    Arruda, E.M.5
  • 16
    • 34548574690 scopus 로고    scopus 로고
    • Age-and site-associated biomechanical weakening of human articular cartilage of the femoral condyle
    • Temple MM, Bae WC, Chen MQ, Lotz M, Amiel D, Coutts RD, Sah RL. 2007 Age-and site-associated biomechanical weakening of human articular cartilage of the femoral condyle. Osteoarthritis Cartilage 15, 1042-1052.(doi:10.1016/j.joca.2007.03.005)
    • (2007) Osteoarthritis Cartilage , vol.15 , pp. 1042-1052
    • Temple, M.M.1    Bae, W.C.2    Chen, M.Q.3    Lotz, M.4    Amiel, D.5    Coutts, R.D.6    Sah, R.L.7
  • 17
    • 22644447052 scopus 로고    scopus 로고
    • Variation of cell and matrix morphologies in articular cartilage among locations in the adult human knee
    • Quinn TM, Hunziker EB, Häuselmann H-J. 2005 Variation of cell and matrix morphologies in articular cartilage among locations in the adult human knee. Osteoarthritis Cartilage 13, 672-678.(doi:10.1016/j.joca.2005.04.011)
    • (2005) Osteoarthritis Cartilage , vol.13 , pp. 672-678
    • Quinn, T.M.1    Hunziker, E.B.2    Häuselmann, H.-J.3
  • 18
    • 84888876280 scopus 로고    scopus 로고
    • Cell and matrix morphology in articular cartilage from adult human knee and ankle joints suggests depth-associated adaptations to biomechanical and anatomical roles
    • Quinn TM, Häuselmann H-J, Shintani N, Hunziker EB. 2013 Cell and matrix morphology in articular cartilage from adult human knee and ankle joints suggests depth-associated adaptations to biomechanical and anatomical roles. Osteoarthritis Cartilage 21, 1904-1912.(doi:10.1016/j.joca.2013.09.011)
    • (2013) Osteoarthritis Cartilage , vol.21 , pp. 1904-1912
    • Quinn, T.M.1    Häuselmann, H.-J.2    Shintani, N.3    Hunziker, E.B.4
  • 20
    • 77956301003 scopus 로고    scopus 로고
    • A review of probabilistic analysis in orthopaedic biomechanics
    • Laz PJ, Browne M. 2010 A review of probabilistic analysis in orthopaedic biomechanics. Proc. Inst. Mech. Eng. H 224, 927-943.(doi:10.1243?09544119JEIM739)
    • (2010) Proc. Inst. Mech. Eng. H , vol.224 , pp. 927-943
    • Laz, P.J.1    Browne, M.2
  • 21
    • 80051552992 scopus 로고    scopus 로고
    • Adaptive surrogate modeling for expedited estimation of nonlinear tissue properties through inverse finite element analysis
    • Halloran JP, Erdemir A. 2011 Adaptive surrogate modeling for expedited estimation of nonlinear tissue properties through inverse finite element analysis. Ann. Biomed. Eng. 39, 2388-2397.(doi:10.1007/s10439-011-0317-2)
    • (2011) Ann. Biomed. Eng , vol.39 , pp. 2388-2397
    • Halloran, J.P.1    Erdemir, A.2
  • 22
    • 84879884448 scopus 로고    scopus 로고
    • A multiscale approach in the computational modeling of the biophysical environment in artificial cartilage tissue regeneration
    • Causin P, Sacco R, Verri M. 2013 A multiscale approach in the computational modeling of the biophysical environment in artificial cartilage tissue regeneration. Biomech. Model. Mechanobiol. 12, 763-780.(doi:10.1007/s10237-012-0440-5)
    • (2013) Biomech. Model. Mechanobiol , vol.12 , pp. 763-780
    • Causin, P.1    Sacco, R.2    Verri, M.3
  • 23
    • 84886413409 scopus 로고    scopus 로고
    • Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes
    • Sibole SC, Maas S, Halloran JP, Weiss JA, Erdemir A. 2013 Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes. Comput. Methods Biomech. Biomed. Eng. 16, 1112-1126.(doi:10.1080/10255842.2013.809711)
    • (2013) Comput. Methods Biomech. Biomed. Eng , vol.16 , pp. 1112-1126
    • Sibole, S.C.1    Maas, S.2    Halloran, J.P.3    Weiss, J.A.4    Erdemir, A.5
  • 24
    • 84969728114 scopus 로고    scopus 로고
    • Subjectspecific analysis of joint contact mechanics: Application to the study of osteoarthritis and surgical planning
    • Henak CR, Anderson AE, Weiss JA. 2013 Subjectspecific analysis of joint contact mechanics: application to the study of osteoarthritis and surgical planning. J. Biomech. Eng. 135, 021003.(doi:10.1115/1.4023386)
    • (2013) J. Biomech. Eng , vol.135
    • Henak, C.R.1    Erson, A.E.2    Weiss, J.A.3
  • 25
    • 84861375865 scopus 로고    scopus 로고
    • Chondrocyte deformations as a function of tibiofemoral joint loading predicted by a generalized high-throughput pipeline of multi-scale simulations
    • Sibole SC, Erdemir A. 2012 Chondrocyte deformations as a function of tibiofemoral joint loading predicted by a generalized high-throughput pipeline of multi-scale simulations. PLoS ONE 7, e37538.(doi:10.1371/journal.pone.0037538)
    • (2012) Plos ONE , vol.7
    • Sibole, S.C.1    Erdemir, A.2
  • 28
    • 33845952109 scopus 로고    scopus 로고
    • Model-based estimation of muscle forces exerted during movements
    • Erdemir A, McLean S, Herzog W, van den Bogert AJ. 2007 Model-based estimation of muscle forces exerted during movements. Clin. Biomech. 22, 131-154.(doi:10.1016/j.clinbiomech.2006.09.005)
    • (2007) Clin. Biomech , vol.22 , pp. 131-154
    • Erdemir, A.1    McLean, S.2    Herzog, W.3    Van Den Bogert, A.J.4
  • 29
    • 28044457460 scopus 로고    scopus 로고
    • A modeling framework to estimate patellofemoral joint cartilage stress in vivo
    • Besier TF, Gold GE, Beaupré GS, Delp SL. 2005 A modeling framework to estimate patellofemoral joint cartilage stress in vivo. Med. Sci. Sports Exerc. 37, 1924-1930.(doi:10.1249/01.mss.0000176686.18683.64)
    • (2005) Med. Sci. Sports Exerc , vol.37 , pp. 1924-1930
    • Besier, T.F.1    Gold, G.E.2    Beaupré, G.S.3    Delp, S.L.4
  • 30
    • 84875370250 scopus 로고    scopus 로고
    • Computational investigation of in situ chondrocyte deformation and actin cytoskeleton remodelling under physiological loading
    • Dowling EP, Ronan W, McGarry JP. 2013 Computational investigation of in situ chondrocyte deformation and actin cytoskeleton remodelling under physiological loading. Acta Biomater. 9, 5943-5955.(doi:10.1016/j.actbio.2012.12.021)
    • (2013) Acta Biomater , vol.9 , pp. 5943-5955
    • Dowling, E.P.1    Ronan, W.2    McGarry, J.P.3
  • 31
    • 84865674799 scopus 로고    scopus 로고
    • Multiscale model predicts tissue-level failure from collagen fiber-level damage
    • Hadi MF, Sander EA, Barocas VH. 2012 Multiscale model predicts tissue-level failure from collagen fiber-level damage. J. Biomech. Eng. 134, 091005.(doi:10.1115/1.4007097)
    • (2012) J. Biomech. Eng , vol.134
    • Hadi, M.F.1    Sander, E.A.2    Barocas, V.H.3
  • 32
    • 84887848215 scopus 로고    scopus 로고
    • Multiphasic finite element framework for modeling hydrated mixtures with multiple neutral and charged solutes
    • Ateshian GA, Maas S, Weiss JA. 2013 Multiphasic finite element framework for modeling hydrated mixtures with multiple neutral and charged solutes. J. Biomech. Eng. 135, 111001.(doi:10.1115/1.4024823)
    • (2013) J. Biomech. Eng , vol.135
    • Ateshian, G.A.1    Maas, S.2    Weiss, J.A.3
  • 33
    • 27744598794 scopus 로고    scopus 로고
    • The role of computational models in the search for the mechanical behavior and damage mechanisms of articular cartilage
    • Wilson W, van Donkelaar CC, van Rietbergen R, Huiskes R. 2005 The role of computational models in the search for the mechanical behavior and damage mechanisms of articular cartilage. Med. Eng. Phys. 27, 810-826.(doi:10.1016/j.medengphy.2005.03.004)
    • (2005) Med. Eng. Phys , vol.27 , pp. 810-826
    • Wilson, W.1    Van Donkelaar, C.C.2    Van Rietbergen, R.3    Huiskes, R.4
  • 35
    • 84886928031 scopus 로고    scopus 로고
    • The influence of size, clearance, cartilage properties, thickness and hemiarthroplasty on the contact mechanics of the hip joint with biphasic layers
    • Li J, Stewart TD, Jin Z, Wilcox RK, Fisher J. 2013 The influence of size, clearance, cartilage properties, thickness and hemiarthroplasty on the contact mechanics of the hip joint with biphasic layers. J. Biomech. 46, 1641-1647.(doi:10.1016/j.jbiomech.2013.04.009)
    • (2013) J. Biomech , vol.46 , pp. 1641-1647
    • Li, J.1    Stewart, T.D.2    Jin, Z.3    Wilcox, R.K.4    Fisher, J.5
  • 36
    • 0034841435 scopus 로고    scopus 로고
    • Depth-dependent compressive properties of normal aged human femoral head articular cartilage: Relationship to fixed charge density
    • Chen SS, Falcovitz YH, Schneiderman R, Maroudas A, Sah RL. 2001 Depth-dependent compressive properties of normal aged human femoral head articular cartilage: relationship to fixed charge density. Osteoarthritis Cartilage 9, 561-569.(doi:10.1053/joca.2001.0424)
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 561-569
    • Chen, S.S.1    Falcovitz, Y.H.2    Schneiderman, R.3    Maroudas, A.4    Sah, R.L.5
  • 37
    • 68149171475 scopus 로고    scopus 로고
    • Modeling the matrix of articular cartilage using a continuous fiber angular distribution predicts many observed phenomena
    • Ateshian GA, Rajan V, Chahine NO, Canal CE, Hung CT. 2009 Modeling the matrix of articular cartilage using a continuous fiber angular distribution predicts many observed phenomena. J. Biomech. Eng. 131, 061003.(doi:10.1115/1.3118773)
    • (2009) J. Biomech. Eng , vol.131
    • Ateshian, G.A.1    Rajan, V.2    Chahine, N.O.3    Canal, C.E.4    Hung, C.T.5
  • 38
    • 84923184709 scopus 로고    scopus 로고
    • A modeling and simulation pipeline for the prediction of localized cartilage mechanics: Towards a multiscale analysis framework for joint, tissue, and cell scales
    • Boston, MA, USA, 6-11 July 2014
    • Reddy A, Erdemir A. 2014 A modeling and simulation pipeline for the prediction of localized cartilage mechanics: towards a multiscale analysis framework for joint, tissue, and cell scales. In 7th World Congress of Biomechanics, Boston, MA, USA, 6-11 July 2014.
    • (2014) 7Th World Congress of Biomechanics
    • Reddy, A.1    Erdemir, A.2
  • 39
    • 85020728805 scopus 로고    scopus 로고
    • Parametric modeling for in silico explorations of cartilage and chondrocyte mechanics
    • Amsterdam, The Netherlands, 13-15 October 2014
    • Erdemir A, Reddy A. 2014 Parametric modeling for in silico explorations of cartilage and chondrocyte mechanics. In 12th Int. Symp. on Computer Methods in Biomechanics and Biomedical Engineering, Amsterdam, The Netherlands, 13-15 October 2014.
    • (2014) 12Th Int. Symp. On Computer Methods in Biomechanics and Biomedical Engineering
    • Erdemir, A.1    Reddy, A.2
  • 40
    • 0036533575 scopus 로고    scopus 로고
    • Horizontally oriented clusters of multiple chondrons in the superficial zone of ankle, but not knee articular cartilage
    • Schumacher BL, Su J-L, Lindley KM, Kuettner KE, Cole AA. 2002 Horizontally oriented clusters of multiple chondrons in the superficial zone of ankle, but not knee articular cartilage. Anat. Rec. 266, 241-248.(doi:10.1002/ar.10063)
    • (2002) Anat. Rec , vol.266 , pp. 241-248
    • Schumacher, B.L.1    Su, J.-L.2    Lindley, K.M.3    Kuettner, K.E.4    Cole, A.A.5
  • 41
    • 84908253920 scopus 로고    scopus 로고
    • The structure and function of the pericellular matrix of articular cartilage
    • Wilusz RE, Sanchez-Adams J, Guilak F. 2014 The structure and function of the pericellular matrix of articular cartilage. Matrix Biol. J. 39C, 25-32.(doi:10.1016/j.matbio.2014.08.009)
    • (2014) Matrix Biol. J , vol.39C , pp. 25-32
    • Wilusz, R.E.1    Sanchez-Adams, J.2    Guilak, F.3
  • 42
    • 84919842218 scopus 로고    scopus 로고
    • Automated generation of tissue-specific three-dimensional finite element meshes containing ellipsoidal cellular inclusions
    • Bennetts CJ, Sibole S, Erdemir A. 2015 Automated generation of tissue-specific three-dimensional finite element meshes containing ellipsoidal cellular inclusions. Comput. Methods Biomech. Biomed. Eng. 18, 1293-1304.(doi:10.1080/10255842.2014.900545)
    • (2015) Comput. Methods Biomech. Biomed. Eng , vol.18 , pp. 1293-1304
    • Bennetts, C.J.1    Sibole, S.2    Erdemir, A.3
  • 43
    • 77249158791 scopus 로고    scopus 로고
    • Composition of the pericellular matrix modulates the deformation behaviour of chondrocytes in articular cartilage under static loading
    • Julkunen P, Wilson W, Jurvelin JS, Korhonen RK. 2009 Composition of the pericellular matrix modulates the deformation behaviour of chondrocytes in articular cartilage under static loading. Med. Biol. Eng. Comput. 47, 1281-1290.(doi:10.1007/s11517-009-0547-8)
    • (2009) Med. Biol. Eng. Comput , vol.47 , pp. 1281-1290
    • Julkunen, P.1    Wilson, W.2    Jurvelin, J.S.3    Korhonen, R.K.4
  • 44
    • 0036269585 scopus 로고    scopus 로고
    • Elastic anisotropy of articular cartilage is associated with the microstructures of collagen fibers and chondrocytes
    • Wu JZ, Herzog W. 2002 Elastic anisotropy of articular cartilage is associated with the microstructures of collagen fibers and chondrocytes. J. Biomech. 35, 931-942.(doi:10.1016/S0021-9290(02)00050-7)
    • (2002) J. Biomech , vol.35 , pp. 931-942
    • Wu, J.Z.1    Herzog, W.2
  • 45
    • 8644290775 scopus 로고    scopus 로고
    • Multi-scale second-order computational homogenization of multi-phase materials: A nested finite element solution strategy
    • Kouznetsova VG, Geers MGD, Brekelmans WAM. 2004 Multi-scale second-order computational homogenization of multi-phase materials: a nested finite element solution strategy. Comput. Methods Appl. Mech. Eng. 193, 5525-5550.(doi:10.1016/j.cma.2003.12.073)
    • (2004) Comput. Methods Appl. Mech. Eng , vol.193 , pp. 5525-5550
    • Kouznetsova, V.G.1    Geers, M.2    Brekelmans, W.3
  • 46
    • 0033811124 scopus 로고    scopus 로고
    • The mechanical environment of the chondrocyte: A biphasic finite element model of cell-matrix interactions in articular cartilage
    • Guilak F, Mow VC. 2000 The mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interactions in articular cartilage. J. Biomech. 33, 1663-1673.(doi:10.1016/S0021-9290(00)00105-6)
    • (2000) J. Biomech , vol.33 , pp. 1663-1673
    • Guilak, F.1    Mow, V.C.2
  • 47
    • 84865662108 scopus 로고    scopus 로고
    • Mechanical behaviour of in situ chondrocytes subjected to different loading rates: A finite element study
    • Moo EK, Herzog W, Han SK, Abu Osman NA, Pingguan-Murphy B, Federico S. 2012 Mechanical behaviour of in situ chondrocytes subjected to different loading rates: a finite element study. Biomech. Model. Mechanobiol. 11, 983-993.(doi:10.1007/s10237-011-0367-2)
    • (2012) Biomech. Model. Mechanobiol , vol.11 , pp. 983-993
    • Moo, E.K.1    Herzog, W.2    Han, S.K.3    Abu Osman, N.A.4    Pingguan-Murphy, B.5    Federico, S.6
  • 48
    • 0036638042 scopus 로고    scopus 로고
    • Quantitative structural organization of normal adult human articular cartilage
    • Hunziker EB, Quinn TM, Häuselmann H-J. 2002 Quantitative structural organization of normal adult human articular cartilage. Osteoarthritis Cartilage 10, 564-572.(doi:10.1053/joca.2002.0814)
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 564-572
    • Hunziker, E.B.1    Quinn, T.M.2    Häuselmann, H.-J.3
  • 49
    • 85047887034 scopus 로고    scopus 로고
    • In situ measurements of chondrocyte deformation under transient loading
    • discussion 111
    • Chahine NO, Hung CT, Ateshian GA. 2007 In situ measurements of chondrocyte deformation under transient loading. Eur. Cell Mater. 13, 100-111; discussion 111.
    • (2007) Eur. Cell Mater , vol.13 , pp. 100-111
    • Chahine, N.O.1    Hung, C.T.2    Ateshian, G.A.3
  • 50
    • 84923184705 scopus 로고    scopus 로고
    • Convergence of representative volume elements for prediction of chondrocyte mechanics in multiscale simulations of cartilage
    • Boston, MA, USA, 6-11 July 2014
    • Davis S, Erdemir A. 2014 Convergence of representative volume elements for prediction of chondrocyte mechanics in multiscale simulations of cartilage. In 7th World Congress of Biomechanics, Boston, MA, USA, 6-11 July 2014.
    • (2014) 7Th World Congress of Biomechanics
    • Davis, S.1    Erdemir, A.2
  • 51
    • 84886413409 scopus 로고    scopus 로고
    • Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes
    • In press, 10. 1080/10255842.2013.869043
    • Sibole SC, Maas S, Halloran JP, Weiss JA, Erdemir A. In press. Evaluation of a post-processing approach for multiscale analysis of biphasic mechanics of chondrocytes, doi:10.1080/10255842.2013.809711. Comput. Methods Biomech. Biomed. Eng.(doi:10. 1080/10255842.2013.869043)
    • Comput. Methods Biomech. Biomed. Eng
    • Sibole, S.C.1    Maas, S.2    Halloran, J.P.3    Weiss, J.A.4    Erdemir, A.5
  • 52
    • 84923184701 scopus 로고    scopus 로고
    • FEBio, finite elements for biomechanics, user’s manual, v. 1.8. Musculoskeletal Research Laboratories, University of Utah
    • Maas S, Rawlins D, Weiss J, Ateshian G. 2013 FEBio, finite elements for biomechanics, user’s manual, v. 1.8. Musculoskeletal Research Laboratories, University of Utah.
    • (2013)
    • Maas, S.1    Rawlins, D.2    Weiss, J.3    Ateshian, G.4
  • 55
    • 1642370513 scopus 로고    scopus 로고
    • Solving unsymmetric sparse systems of linear equations with PARDISO
    • Schenk O, Gärtner K. 2004 Solving unsymmetric sparse systems of linear equations with PARDISO. Future Gen. Comput. Syst. 20, 475-487.(doi:10.1016/j.future.2003.07.011)
    • (2004) Future Gen. Comput. Syst , vol.20 , pp. 475-487
    • Schenk, O.1    Gärtner, K.2
  • 56
    • 47149103447 scopus 로고    scopus 로고
    • Importance of collagen orientation and depthdependent fixed charge densities of cartilage on mechanical behavior of chondrocytes
    • Korhonen RK, Julkunen P, Wilson W, Herzog W. 2008 Importance of collagen orientation and depthdependent fixed charge densities of cartilage on mechanical behavior of chondrocytes. J. Biomech. Eng. 130, 021003.(doi:10.1115/1.2898725)
    • (2008) J. Biomech. Eng , vol.130 , Issue.21003
    • Korhonen, R.K.1    Julkunen, P.2    Wilson, W.3    Herzog, W.4
  • 57
    • 8644240255 scopus 로고    scopus 로고
    • Anisotropic, threedimensional deformation of single attached cells under compression
    • Peeters EAG, Bouten CVC, Oomens CWJ, Bader DL, Snoeckx LHEH, Baaijens FPT. 2004 Anisotropic, threedimensional deformation of single attached cells under compression. Ann. Biomed. Eng. 32, 1443-1452.(doi:10.1114/B:ABME.0000042231.59230.72)
    • (2004) Ann. Biomed. Eng , vol.32 , pp. 1443-1452
    • Peeters, E.1    Bouten, C.2    Oomens, C.3    Bader, D.L.4    Snoeckx, L.5    Baaijens, F.6
  • 58
    • 33846187562 scopus 로고    scopus 로고
    • Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis
    • Horton WE, Bennion P, Yang L. 2006 Cellular, molecular, and matrix changes in cartilage during aging and osteoarthritis. J. Musculoskelet. Neuronal Interact. 6, 379-381.
    • (2006) J. Musculoskelet. Neuronal Interact , vol.6 , pp. 379-381
    • Horton, W.E.1    Bennion, P.2    Yang, L.3
  • 59
    • 84923184697 scopus 로고    scopus 로고
    • Multiscale cartilage biomechanics: Technical challenges in realizing a high-throughput modeling and simulation workflow
    • Boston, MA, USA, 6-11 July 2014
    • Erdemir A. 2014 Multiscale cartilage biomechanics: technical challenges in realizing a high-throughput modeling and simulation workflow. In 7th World Congress of Biomechanics, Boston, MA, USA, 6-11 July 2014.
    • (2014) 7Th World Congress of Biomechanics
    • Erdemir, A.1


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