Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179

Nature Communications

Volumn 6, Issue , 2015, Pages

  Nishiguchi, Koji M ^a   Carvalho, Livia S ^a   Rizzi, Matteo ^a   Powell, Kate ^a   Holthaus, Sophia Martha Kleine ^a   Azam, Selina A ^a   Duran, Yanai ^a   Ribeiro, Joana ^a   Luhmann, Ulrich F O ^a   Bainbridge, James W B ^a   Smith, Alexander J ^a   Ali, Robin R ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GPR179 PROTEIN, MOUSE; PDE6B PROTEIN, MOUSE; PHOSPHODIESTERASE VI;

CELL ORGANELLE; GENE EXPRESSION; HERITABILITY; MUTATION; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITE; ELECTRORETINOGRAPHY; GENE MUTATION; GENE THERAPY; MOUSE; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PHOTORECEPTOR; VISION; VISUAL ACUITY; ANIMAL; BIOLOGICAL MODEL; C3H MOUSE; C57BL MOUSE; CROSS BREEDING; DEPENDOPARVOVIRUS; EYE FUNDUS; FEAR; FEMALE; GENETICS; GENOTYPE; HOMOZYGOTE; HUMAN; MALE; METABOLISM; MUTATION; PLASMID; PROCEDURES; RETINA DEGENERATION; TIME FACTOR; TRANSGENIC MOUSE;

MUS;

ANIMALS; CROSSES, GENETIC; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 6; DEPENDOVIRUS; ELECTRORETINOGRAPHY; FEAR; FEMALE; FUNDUS OCULI; GENETIC THERAPY; GENOTYPE; HOMOZYGOTE; HUMANS; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, GENETIC; MUTATION; PLASMIDS; RECEPTORS, G-PROTEIN-COUPLED; RETINAL DEGENERATION; TIME FACTORS; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84923164012     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7006     Document Type: Article

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