LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation

EMBO Journal

Volumn 34, Issue 4, 2015, Pages 475-490

  Tan, Xiaojun ^a   Sun, Yue ^a   Thapa, Narendra ^a   Liao, Yihan ^a   Hedman, Andrew C ^a   Anderson, Richard A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

EGFR; LAPTM4B; PIPKI i5; PtdIns(4,5)P2

Indexed keywords

CD63 ANTIGEN; EPIDERMAL GROWTH FACTOR RECEPTOR; LYSOSOMAL ASSOCIATED PROTEIN TRANSMEMBRANE 4B; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE PROTEIN; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; UNCLASSIFIED DRUG; LAPTM4B PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL; PROTEIN BINDING; SNX5 PROTEIN, HUMAN; SORTING NEXIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SELECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOSOME; GENE OVEREXPRESSION; INTERNALIZATION; LYSOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; UBIQUITINATION; BIOLOGICAL MODEL; CELL LINE; FLUORESCENCE MICROSCOPY; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

CELL LINE; HUMANS; LYSOSOMES; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; ONCOGENE PROTEINS; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SORTING NEXINS;

EID: 84923103081     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201489425     Document Type: Article

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