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Volumn 6, Issue , 2015, Pages

Tumour suppressor TRIM33 targets nuclear β-catenin degradation

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN KINASE C DELTA; SERINE; TRIPARTITE MOTIF CONTAINING PROTEIN 33; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; TRANSCRIPTION FACTOR; TRIM33 PROTEIN, HUMAN;

EID: 84923070705     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7156     Document Type: Article
Times cited : (136)

References (41)
  • 1
    • 84862171364 scopus 로고    scopus 로고
    • The many faces and functions of b-catenin
    • Valenta, T., Hausmann, G. & Basler, K. The many faces and functions of b-catenin. EMBO J. 31, 2714-2736 (2012).
    • (2012) EMBO J. , vol.31 , pp. 2714-2736
    • Valenta, T.1    Hausmann, G.2    Basler, K.3
  • 2
    • 84877730578 scopus 로고    scopus 로고
    • Wnt stabilization of b-catenin reveals principles for morphogen receptor-scaffold assemblies
    • Kim, S. E. et al. Wnt stabilization of b-catenin reveals principles for morphogen receptor-scaffold assemblies. Science 340, 867-870 (2013).
    • (2013) Science , vol.340 , pp. 867-870
    • Kim, S.E.1
  • 3
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald, B. T., Tamai, K. & He, X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17, 9-26 (2009).
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 4
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/b-catenin signaling and disease
    • Clevers, H. & Nusse, R. Wnt/b-catenin signaling and disease. Cell 149, 1192-1205 (2012).
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 5
    • 82555170271 scopus 로고    scopus 로고
    • Nuclear PKM2 regulates b-catenin transactivation upon EGFR activation
    • Yang, W. et al. Nuclear PKM2 regulates b-catenin transactivation upon EGFR activation. Nature 480, 118-122 (2011).
    • (2011) Nature , vol.480 , pp. 118-122
    • Yang, W.1
  • 6
    • 4644231786 scopus 로고    scopus 로고
    • Wnt-independent beta-catenin transactivation in tumor development
    • Lu, Z. & Hunter, T. Wnt-independent beta-catenin transactivation in tumor development. Cell Cycle 3, 571-573 (2004).
    • (2004) Cell Cycle , vol.3 , pp. 571-573
    • Lu, Z.1    Hunter, T.2
  • 7
    • 79960334547 scopus 로고    scopus 로고
    • EGFR signaling regulates tumor cell migration in craniopharyngiomas
    • Hölsken, A. EGFR signaling regulates tumor cell migration in craniopharyngiomas. Clin. Cancer Res. 17, 4367-4377 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , pp. 4367-4377
    • Hölsken, A.1
  • 8
    • 84871846692 scopus 로고    scopus 로고
    • WNT signalling pathways as therapeutic targets in cancer
    • Anastas, J. N. & Moon, R. T. WNT signalling pathways as therapeutic targets in cancer. Nat. Rev. Cancer 13, 11-26 (2013).
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 11-26
    • Anastas, J.N.1    Moon, R.T.2
  • 9
    • 84881425239 scopus 로고    scopus 로고
    • C-Cbl, a ubiquitin E3 ligase that targets active b-catenin: A novel layer of Wnt signaling regulation
    • Chitalia, V. et al. c-Cbl, a ubiquitin E3 ligase that targets active b-catenin: a novel layer of Wnt signaling regulation. J. Biol. Chem. 288, 23505-23517 (2013).
    • (2013) J. Biol. Chem. , vol.288 , pp. 23505-23517
    • Chitalia, V.1
  • 10
    • 80054848955 scopus 로고    scopus 로고
    • TRIM proteins and cancer
    • Hatakeyama, S. TRIM proteins and cancer. Nat. Rev. Cancer 11, 792-804 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 792-804
    • Hatakeyama, S.1
  • 11
    • 19344371219 scopus 로고    scopus 로고
    • The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis
    • Ransom, D. G. et al. The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol 2, E237 (2004).
    • (2004) PLoS Biol , vol.2 , pp. E237
    • Ransom, D.G.1
  • 12
    • 84887503435 scopus 로고    scopus 로고
    • Tripartite Motif-containing 33 (TRIM33) protein functions in the poly (ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein
    • Kulkarni, A. et al. Tripartite Motif-containing 33 (TRIM33) protein functions in the poly (ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein. J. Biol. Chem. 288, 32357-32369 (2013).
    • (2013) J. Biol. Chem. , vol.288 , pp. 32357-32369
    • Kulkarni, A.1
  • 13
    • 84884906650 scopus 로고    scopus 로고
    • Transcriptional intermediary factor 1g binds to the anaphase-promoting complex/cyclosome and promotes mitosis
    • Sedgwick, G. G. et al. Transcriptional intermediary factor 1g binds to the anaphase-promoting complex/cyclosome and promotes mitosis. Oncogene 32, 4622-4633 (2013).
    • (2013) Oncogene , vol.32 , pp. 4622-4633
    • Sedgwick, G.G.1
  • 14
    • 77954301966 scopus 로고    scopus 로고
    • TIF1gamma controls erythroid cell fate by regulating transcription elongation
    • Bai, X. et al. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell 142, 133-143 (2010).
    • (2010) Cell , vol.142 , pp. 133-143
    • Bai, X.1
  • 15
    • 79957917231 scopus 로고    scopus 로고
    • Transcription intermediary factor 1g is a tumor suppressor in mouse and human chronic myelomonocytic leukemia
    • Aucagne, R. et al. Transcription intermediary factor 1g is a tumor suppressor in mouse and human chronic myelomonocytic leukemia. J. Clin. Invest. 121, 2361-2370 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 2361-2370
    • Aucagne, R.1
  • 16
    • 33646876973 scopus 로고    scopus 로고
    • Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway
    • He, W. et al. Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. Cell 125, 929-941 (2006).
    • (2006) Cell , vol.125 , pp. 929-941
    • He, W.1
  • 17
    • 58149093172 scopus 로고    scopus 로고
    • FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
    • Dupont, S. et al. FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination. Cell 136, 123-135 (2009).
    • (2009) Cell , vol.136 , pp. 123-135
    • Dupont, S.1
  • 18
    • 79957738075 scopus 로고    scopus 로고
    • Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
    • Herquel, B. et al. Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma. Proc. Natl Acad. Sci. USA 108, 8212-8217 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 8212-8217
    • Herquel, B.1
  • 19
    • 68249108045 scopus 로고    scopus 로고
    • Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas
    • Vincent, D. F. et al. Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas. PLoS Genet. 5, e1000575 (2009).
    • (2009) PLoS Genet. , vol.5 , pp. e1000575
    • Vincent, D.F.1
  • 20
    • 84861610442 scopus 로고    scopus 로고
    • Tif1g suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway
    • Vincent, D. F. et al. Tif1g suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway. Am. J. Pathol. 180, 2214-2221 (2012).
    • (2012) Am. J. Pathol. , vol.180 , pp. 2214-2221
    • Vincent, D.F.1
  • 21
    • 0032801892 scopus 로고    scopus 로고
    • Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression
    • Kolligs, F. T., Hu, G., Dang, C. V. & Fearon, E. R. Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression. Mol. Cell. Biol. 19, 5696-5706 (1999).
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5696-5706
    • Kolligs, F.T.1    Hu, G.2    Dang, V.C.3    Fearon, E.R.4
  • 22
    • 0033034120 scopus 로고    scopus 로고
    • Beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation
    • Liu, C. et al. beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation. Proc. Natl Acad. Sci. USA 96, 6273-6278 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 6273-6278
    • Liu, C.1
  • 23
    • 84875231510 scopus 로고    scopus 로고
    • Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?
    • Nathan, J. A., Kim, H. T., Ting, L., Gygi, S. P. & Goldberg, A. L. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? EMBO J. 32, 552-565 (2013).
    • (2013) EMBO J. , vol.32 , pp. 552-565
    • Nathan, J.A.1    Kim, H.T.2    Ting, L.3    Gygi, S.P.4    Goldberg, A.L.5
  • 24
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu, C. et al. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108, 837-847 (2002).
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1
  • 26
    • 84880418571 scopus 로고    scopus 로고
    • CUL3 and protein kinases: Insights from PLK1/KLHL22 interaction
    • Metzger, T., Kleiss, C. & Sumara, I. CUL3 and protein kinases: insights from PLK1/KLHL22 interaction. Cell Cycle 12, 2291-2296 (2013).
    • (2013) Cell Cycle , vol.12 , pp. 2291-2296
    • Metzger, T.1    Kleiss, C.2    Sumara, I.3
  • 27
    • 0033068154 scopus 로고    scopus 로고
    • The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro
    • Winston, J. T. et al. The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. Genes Dev. 13, 270-283 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 270-283
    • Winston, J.T.1
  • 28
    • 0035947083 scopus 로고    scopus 로고
    • Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein
    • Liu, J. et al. Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol. Cell 7, 927-936 (2001).
    • (2001) Mol. Cell , vol.7 , pp. 927-936
    • Liu, J.1
  • 29
    • 53349162212 scopus 로고    scopus 로고
    • Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL
    • Chitalia, V. C. et al. Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat. Cell Biol. 10, 1208-1216 (2008).
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1208-1216
    • Chitalia, V.C.1
  • 30
    • 33745081761 scopus 로고    scopus 로고
    • Protein kinase C delta inhibits Caco-2 cell proliferation by selective changes in cell cycle and cell death regulators
    • Cerda, S. R. et al. Protein kinase C delta inhibits Caco-2 cell proliferation by selective changes in cell cycle and cell death regulators. Oncogene 25, 3123-3138 (2006).
    • (2006) Oncogene , vol.25 , pp. 3123-3138
    • Cerda, S.R.1
  • 31
    • 0033521742 scopus 로고    scopus 로고
    • PKCdelta acts as a growth and tumor suppressor in rat colonic epithelial cells
    • Perletti, G. P., Marras, E., Concari, P., Piccinini, F. & Tashjian, Jr A. H. PKCdelta acts as a growth and tumor suppressor in rat colonic epithelial cells. Oncogene 18, 1251-1256 (1999).
    • (1999) Oncogene , vol.18 , pp. 1251-1256
    • Perletti, G.P.1    Marras, E.2    Concari, P.3    Piccinini, F.4    Tashjian, Jr.A.H.5
  • 32
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle, H., Bauer, A., Stappert, J., Kispert, A. & Kemler, R. beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16, 3797-3804 (1997).
    • (1997) EMBO J. , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 33
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
    • Wu, X. et al. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 133, 340-353 (2008).
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1
  • 34
    • 0038267245 scopus 로고    scopus 로고
    • CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling
    • Song, D. H. et al. CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J. Biol. Chem. 278, 24018-24025 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 24018-24025
    • Song, D.H.1
  • 35
    • 34249661591 scopus 로고    scopus 로고
    • Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity
    • Fang, D. et al. Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. J. Biol. Chem. 282, 11221-11229 (2007).
    • (2007) J. Biol. Chem. , vol.282 , pp. 11221-11229
    • Fang, D.1
  • 36
    • 84857364721 scopus 로고    scopus 로고
    • A Rac1/PAK1 cascade controls b-catenin activation in colon cancer cells
    • Zhu, G. et al. A Rac1/PAK1 cascade controls b-catenin activation in colon cancer cells. Oncogene 31, 1001-1012 (2012).
    • (2012) Oncogene , vol.31 , pp. 1001-1012
    • Zhu, G.1
  • 38
    • 84893835907 scopus 로고    scopus 로고
    • Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-b-dependent cancer metastasis
    • Xue, J. et al. Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-b-dependent cancer metastasis. J. Clin. Invest. 124, 564-579 (2014).
    • (2014) J. Clin. Invest. , vol.124 , pp. 564-579
    • Xue, J.1
  • 39
    • 84877012261 scopus 로고    scopus 로고
    • Pharmacological modulation of beta-catenin and its applications in cancer therapy
    • Thakur, R. & Mishra, D. P. Pharmacological modulation of beta-catenin and its applications in cancer therapy. J. Cell. Mol. Med. 17, 449-456 (2013).
    • (2013) J. Cell. Mol. Med. , vol.17 , pp. 449-456
    • Thakur, R.1    Mishra, D.P.2
  • 40
    • 80054774352 scopus 로고    scopus 로고
    • FoxM1 promotes beta-cateninnuclear localization and controls Wnt target-geneexpression and glioma tumorigenesis
    • Zhang, N. et al. FoxM1 promotes beta-cateninnuclear localization and controls Wnt target-geneexpression and glioma tumorigenesis. Cancer Cell 20, 427-442 (2011).
    • (2011) Cancer Cell , vol.20 , pp. 427-442
    • Zhang, N.1
  • 41
    • 57149103930 scopus 로고    scopus 로고
    • Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis
    • Huang, F. J. et al. Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis. Cancer Res. 68, 9634-9642 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 9634-9642
    • Huang, F.J.1


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