Autophagy-associated targeting pathways of natural products during cancer treatment

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 24, 2014, Pages 10557-10563

  Zhang, Shu Fang ^a   Wang, Xiao Lu ^a   Yang, Xiao Qi ^a   Chen, Ning ^a  

^a WUHAN SPORTS UNIVERSITY   (China)

Author keywords

Allicin; Autophagy; Curcumin; Epigallocatechin 3 gallate; Ginsenoside; Resveratrol

Indexed keywords

BIOLOGICAL PRODUCT; TUMOR PROTEIN;

ANIMAL; ANTAGONISTS AND INHIBITORS; AUTOPHAGY; DRUG EFFECTS; HUMAN; MOLECULARLY TARGETED THERAPY; NEOPLASMS; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; AUTOPHAGY; BIOLOGICAL PRODUCTS; HUMANS; MOLECULAR TARGETED THERAPY; NEOPLASM PROTEINS; NEOPLASMS; SIGNAL TRANSDUCTION;

EID: 84923038274     PISSN: 15137368     EISSN: None     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.24.10557     Document Type: Short Survey

References (87)

1. Aggarwal BB, Shishodia S, Takada Y, et al (2005). Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. Clin Cancer Res, 11, 7490-8.
2. Ahmad N, Feyes DK, Nieminen AL, et al (1997). Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst, 89, 1881-6.
3. Ajabnoor GM, Crook T, Coley HM (2012). Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells. Cell Death Dis, 3, 260.
4. Alkhalaf M (2007). Resveratrol-induced apoptosis is associated with activation of p53 and inhibition of protein translation in T47D human breast cancer cells. Pharmacol, 80, 134-43.
5. Altonsy MO, Andrews SC (2011). Diallyl disulphide, a beneficial component of garlic oil, causes a redistribution of cell-cycle growth phases, induces apoptosis, and enhances butyrate-induced apoptosis in colorectal adenocarcinoma cells (HT-29). Nutr Cancer, 63, 1104-13.
6. Amagase H (2006). Clarifying the real bioactive constituents of garlic. J Nutr, 136, 716-25.
7. Aoki H, Takada Y, Kondo S, et al (2007). Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol Pharmacol, 72, 29-39.
8. Aras A, Khokhar AR, Qureshi MZ, et al (2014). Targeting cancer with nano-bullets: curcumin, EGCG, resveratrol and quercetin on flying carpets. Asian Pac J Cancer Prev, 15, 3865-71.
9. Aziz MH, Kumar R, Ahmad N (2003). Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review). Int J Oncol, 23, 17-28.
10. Baena R, Salinas P (2014). Diet and cancer: risk factors and epidemiological evidence. Maturitas, 77, 202-8.
11. Balunas MJ, Kinghorn AD (2005). Drug discovery from medicinal plants. Life Sci, 78, 431-41.
12. Banjerdpongchai R, Khaw-On P (2013). Terpinen-4-ol induces autophagic and apoptotic cell death in human leukemic HL-60 cells. Asian Pac J Cancer Prev, 14, 7537-42.
13. Bansal SS, Goel M, Aqil F, et al (2011). Advanced drug delivery systems of curcumin for cancer chemoprevention. Cancer Prev Res (Phila), 4, 1158-71.
14. Bertelli AA, Das DK (2009). Grapes, wines, resveratrol, and heart health. J Cardiovasc Pharmacol, 54, 468-76.
15. Boya P, Gonzalez-Polo RA, Casares N, et al (2005). Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol, 25, 1025-40.
16. Chen N, Karantza-Wadsworth V (2009). Role and regulation of autophagy in cancer. Biochim Biophys Acta, 1793, 1516-23.
17. Chen N, Karantza V (2011). Autophagy as a therapeutic target in cancer. Cancer Biol Ther, 11, 157-68.
18. Cheng Y, Qiu F, Huang J, et al (2008). Apoptosis-suppressing and autophagy-promoting effects of calpain on oridonin-induced L929 cell death. Arch Biochem Biophys, 475, 148-55.
19. Chu YL, Ho CT, Chung JG, et al (2012). Allicin induces p53-mediated autophagy in Hep G2 human liver cancer cells. J Agric Food Chem, 60, 8363-71.
20. Clarke PG (1990). Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol (Berl), 181, 195-213.
21. Clement MV, Hirpara JL, Chawdhury SH, et al (1998). Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. Blood, 92, 996-1002.
22. Cui Q, Tashiro S, Onodera S, et al (2006). Augmentation of oridonin-induced apoptosis observed with reduced autophagy. J Pharmacol Sci, 101, 230-9.
23. Degenhardt K, Mathew R, Beaudoin B, et al (2006). Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell, 10, 51-64.
24. Eccles DM, Cranston G, Steel CM, et al (1990). Allele losses on chromosome 17 in human epithelial ovarian carcinoma. Oncogene, 5, 1599-601.
25. Futreal PA, Soderkvist P, Marks JR, et al (1992). Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. Cancer Res, 52, 2624-7.
26. Gao SM, Yang JJ, Chen CQ, et al (2012). Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells. J Exp Clin Cancer Res, 31, 27.
27. Gao X, Zacharek A, Salkowski A, et al (1995). Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer. Cancer Res, 55, 1002-5.
28. Gossner G, Choi M, Tan L, et al (2007). Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells. Gynecol Oncol, 105, 23-30.
29. Jang M, Cai L, Udeani GO, et al (1997). Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science, 275, 218-20.
30. Jia YL, Li J, Qin ZH, et al (2009). Autophagic and apoptotic mechanisms of curcumin-induced death in K562 cells. J Asian Nat Prod Res, 11, 918-28.
31. Juhasz G, Hill JH, Yan Y, et al (2008). The class III PI (3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. J Cell Biol, 181, 655-66.
32. Kallifatidis G, Hoepfner D, Jaeg T, et al (2013). The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Mar Drugs, 11, 3500-16.
33. Kang HJ, Lee SH, Price JE, et al (2009). Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB in breast cancer cells and potentiates the growth inhibitory effect of paclitaxel in a breast cancer nude mice model. Breast J, 15, 223-9.
34. Kim J, Park EJ (2002). Cytotoxic anticancer candidates from natural resources. Curr Med Chem Anticancer Agents, 2, 485-537.
35. Kim SM, Lee SY, Cho JS, et al (2010). Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB. Eur J Pharmacol, 631, 1-9.
36. Kinghorn AD, Chin YW, Swanson SM (2009). Discovery of natural product anticancer agents from biodiverse organisms. Curr Opin Drug Discov Devel, 12, 189-96.
37. Kiraly-Veghely Z, Tyihak E, Albert L, et al (1998). Identification and measurement of resveratrol and formaldehyde in parts of white and blue grape berries. Acta Biol Hung, 49, 281-9.
38. Klinge CM, Risinger KE, Watts MB, et al (2003). Estrogenic activity in white and red wine extracts. J Agric Food Chem, 51, 1850-7.
39. Kma L (2013). Roles of plant extracts and constituents in cervical cancer therapy. Asian Pac J Cancer Prev, 14, 3429-36.
40. Lachumy SJ, Oon CE, Deivanai S, et al (2013). Herbal remedies for combating irradiation: a green anti-irradiation approach. Asian Pac J Cancer Prev, 14, 5553-65.
41. Lao F, Shang Y, Liu D (2009). Autophagy pathway of raji cell death induced by resveratrol. Chinese J Biologicals, 22, 654-8.
42. Lao Y, Wan G, Liu Z, et al (2014). The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation. Autophagy, 10, 736-49.
43. Larocque K, Ovadje P, Djurdjevic S, et al (2014). Novel analogue of colchicine induces selective pro-death autophagy and necrosis in human cancer cells. PLoS One, 9, 87064.
44. Lee YJ, Kim NY, Suh YA, et al (2011). Involvement of ROS in curcumin-induced autophagic cell death. Korean J Physiol Pharmacol, 15, 1-7.
45. Levine B, Kroemer G (2008). Autophagy in the pathogenesis of disease. Cell, 132, 27-42.
46. Liang XH, Jackson S, Seaman M, et al (1999). Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature, 402, 672-6.
47. Lum JJ, DeBerardinis RJ, Thompson CB (2005). Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol, 6, 439-48.
48. Mai TT, Moon J, Song Y, et al (2012). Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells. Cancer Lett, 321, 144-53.
49. Mathew R, Karp CM, Beaudoin B, et al (2009). Autophagy suppresses tumorigenesis through elimination of p62. Cell, 137, 1062-75.
50. Meiyanto E, Hermawan A, Anindyajati (2012). Natural products for cancer-targeted therapy: citrus flavonoids as potent chemopreventive agents. Asian Pac J Cancer Prev, 13, 427-36.
51. Mizushima N (2010). The role of the Atg1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol, 22, 132-9.
52. Mizushima N, Yoshimori T, Ohsumi Y (2011). The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol, 27, 107-32.
53. Odot J, Albert P, Carlier A, et al (2004). In vitro and in vivo anti-tumoral effect of curcumin against melanoma cells. Int J Cancer, 111, 381-7.
54. Opipari AW, Jr., Tan L, Boitano AE, et al (2004). Resveratrol-induced autophagocytosis in ovarian cancer cells. Cancer Res, 64, 696-703.
55. Pandey S, Chandravati (2012). Autophagy in cervical cancer: an emerging therapeutic target. Asian Pac J Cancer Prev, 13, 4867-71.
56. Park HW, In G, Han ST, et al (2013). Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography. J Ginseng Res, 37, 457-67.
57. Plengsuriyakarn T, Viyanant V, Eursitthichai V, et al (2012). Anticancer activities against cholangiocarcinoma, toxicity and pharmacological activities of Thai medicinal plants in animal models. BMC Complement Altern Med, 12, 23.
58. Qanungo S, Das M, Haldar S, et al (2005). Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells. Carcinogenesis, 26, 958-67.
59. Qian H, Yang Y, Wang X (2011). Curcumin enhanced adriamycin-induced human liver-derived Hepatoma G2 cell death through activation of mitochondria-mediated apoptosis and autophagy. Eur J Pharm Sci, 43, 125-31.
60. Qu X, Yu J, Bhagat G, et al (2003). Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest, 112, 1809-20.
61. Rocque GB, Cleary JF (2013). Palliative care reduces morbidity and mortality in cancer. Nat Rev Clin Oncol, 10, 80-9.
62. Romanov J, Walczak M, Ibiricu I, et al (2012). Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation. EMBO J, 31, 4304-17.
63. Russell SE, Hickey GI, Lowry WS, et al (1990). Allele loss from chromosome 17 in ovarian cancer. Oncogene, 5, 1581-3.
64. Sabolovic N, Heurtaux T, Humbert AC, et al (2007). cis-and trans-Resveratrol are glucuronidated in rat brain, olfactory mucosa and cultured astrocytes. Pharmacol, 80, 185-92.
65. Saito H, Inazawa J, Saito S, et al (1993). Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM region on 17q21.3 often and commonly deleted in tumors. Cancer Res, 53, 3382-5.
66. Satoo K, Noda NN, Kumeta H, et al (2009). The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. EMBO J, 28, 1341-50.
67. Scarlatti F, Bauvy C, Ventruti A, et al (2004). Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. J Biol Chem, 279, 18384-91.
68. Scarlatti F, Maffei R, Beau I, et al (2008). Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ, 15, 1318-29.
69. Shammas MA, Neri P, Koley H, et al (2006). Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications. Blood, 108, 2804-10.
70. Shimizu M, Shirakami Y, Moriwaki H (2008). Targeting receptor tyrosine kinases for chemoprevention by green tea catechin, EGCG. Int J Mol Sci, 9, 1034-49.
71. Shinojima N, Yokoyama T, Kondo Y, et al (2007). Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin-induced autophagy. Autophagy, 3, 635-7.
72. Siddiqui IA, Malik A, Adhami VM, et al (2008). Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis. Oncogene, 27, 2055-63.
73. Tang SN, Singh C, Nall D, et al (2010). The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition. J Mol Signal, 5, 14.
74. Thakur VS, Gupta K, Gupta S (2012). Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylases. Int J Oncol, 41, 353-61.
75. Vidanarachchi JK, Kurukulasuriya MS, Malshani Samaraweera A, et al (2012). Applications of marine nutraceuticals in dairy products. Adv Food Nutr Res, 65, 457-78.
76. Weber WA (2009). Assessing tumor response to therapy. J Nucl Med, 50, 1-10.
77. Weisberger AS, Pensky J (1958). Tumor inhibition by a sulfhydryl-blocking agent related to an active principle of garlic (Allium sativum). Cancer Res, 18, 1301-8.
78. Wessely R, Schomig A, Kastrati A (2006). Sirolimus and Paclitaxel on polymer-based drug-eluting stents: similar but different. J Am Coll Cardiol, 47, 708-14.
79. White E, DiPaola RS (2009). The double-edged sword of autophagy modulation in cancer. Clin Cancer Res, 15, 5308-16.
80. Wu SL, Sun ZJ, Yu L, et al (2004). Effect of resveratrol and in combination with 5-FU on murine liver cancer. World J Gastroenterol, 10, 3048-52.
81. Yang S, Wang X, Contino G, et al (2011). Pancreatic cancers require autophagy for tumor growth. Genes Dev, 25, 717-29.
82. Yang Z, Klionsky DJ (2010). Eaten alive: a history of macroautophagy. Nat Cell Biol, 12, 814-22.
83. Yue Z, Jin S, Yang C, et al (2003). Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA, 100, 15077-82.
84. Zhang C, An L, Fengye J (2002). The research progress of ginseng saponin physiological activity. Food Fermentation Industries, 28, 70-4.
85. Zhang Q, Kang X, Zhao W (2006). Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma. Biochem Biophys Res Commun, 342, 824-8.
86. Zhong LR, Chen X, Wei KM (2013). Radix tetrastigma hemsleyani flavone induces apoptosis in human lung carcinoma a549 cells by modulating the MAPK pathway. Asian Pac J Cancer Prev, 14, 5983-7.
87. Zhou DY, Ding N, Du ZY, et al (2014). Curcumin analogues with high activity for inhibiting human prostate cancer cell growth and androgen receptor activation. Mol Med Rep, 10, 1315-22.