Novel analogue of colchicine induces selective pro-death autophagy and necrosis in human cancer cells

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Larocque, Kristen ^a   Ovadje, Pamela ^a   Djurdjevic, Sinisa ^a   Mehdi, Mariam ^a   Green, James ^a   Pandey, Siyaram ^a  

^a UNIVERSITY OF WINDSOR   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3,8,9,10 TETRAMETHOXYALLOCOLCHICINE; COLCHICINE; COLCHICINE DERIVATIVE; N ACETYL O METHYLCOLCHINOL; N ACETYLCOLCHINOL PHOSPHATE; NSC 51046; REACTIVE OXYGEN METABOLITE; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL LINE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DRUG STRUCTURE; FIBROBLAST; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRION; MOUSE; NONHUMAN; PROTEIN POLYMERIZATION; SELECTIVE AUTOPHAGY; STRUCTURE ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; COLCHICINE; FIBROBLASTS; HUMANS; LEUKEMIA, T-CELL; MALE; MICE; MICE, NUDE; MICROTUBULES; MITOCHONDRIA; NECROSIS; PANCREATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; TUBULIN;

EID: 84899818667     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087064     Document Type: Article

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