Allicin induces p53-mediated autophagy in Hep G2 human liver cancer cells

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 34, 2012, Pages 8363-8371

  Chu, Yung Lin ^a   Ho, Chi Tang ^a,b   Chung, Jing Gung ^c   Rajasekaran, Raghu ^a   Sheen, Lee Yan ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b RUTGERS UNIVERSITY   (United States)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

allicin; autophagy; Hep G2 cells; LC3 II; p53

Indexed keywords

ALLICIN; AUTOPHAGIC CELLS; AUTOPHAGY; BIOACTIVE COMPOUNDS; CHEMOPREVENTIVE AGENTS; COLOCALIZATION; CONFOCAL LASER MICROSCOPY; DIALLYL DISULFIDE; DIALLYL SULFIDE; DIALLYL TRISULFIDES; HEPATOCELLULAR CARCINOMA; HEPATOCELLULAR CARCINOMA CELL; HUMAN LIVER; HUMAN LIVER CANCER CELLS; LC3-II; LIVER CANCERS; P53; SIGNALING PATHWAYS; WESTERN BLOTTING;

CELL CULTURE; CELL DEATH; DEGRADATION; PIGMENTS; SULFUR COMPOUNDS;

DISEASES;

ALLICIN; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; MAP1LC3A PROTEIN, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, HUMAN; SULFINIC ACID DERIVATIVE; TARGET OF RAPAMYCIN KINASE; TUBERIN; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL SURVIVAL; DRUG EFFECT; HEPG2 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; METHODOLOGY; MITOCHONDRIAL MEMBRANE POTENTIAL; PHAGOSOME; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYNTHESIS; TANDEM MASS SPECTROMETRY; TUMOR SUPPRESSOR GENE;

ANTICARCINOGENIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENES, P53; HEP G2 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; PHAGOSOMES; SIGNAL TRANSDUCTION; SULFINIC ACIDS; TANDEM MASS SPECTROMETRY; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

ALLIUM SATIVUM;

EID: 84865650394     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf301298y     Document Type: Article

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