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Volumn 9, Issue 4, 2015, Pages 1345-1350

Piperlongumine reverses doxorubicin resistance through the PI3K/Akt signaling pathway in K562/A02 human leukemia cells

Author keywords

Doxorubicin resistance; Human leukemia; Piperlongumine

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; PIPERLONGUMINE; PROTEIN KINASE B; PROTEIN P27; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; SURVIVIN; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG;

EID: 84922969196     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2015.2254     Document Type: Article
Times cited : (29)

References (26)
  • 2
    • 84894504942 scopus 로고    scopus 로고
    • Loss of Ikaros DNA binding function confers integrin dependent survival on pre B cells and progression to acute lymphoblastic leukemia
    • Joshi I, Yoshida T, Jena N, Qi X, Zhang J, Van Etten RA and Georgopoulos K: Loss of Ikaros DNA binding function confers integrin dependent survival on pre B cells and progression to acute lymphoblastic leukemia. Nat Immunol 15: 294-304, 2014.
    • (2014) Nat Immunol , vol.15 , pp. 294-304
    • Joshi, I.1    Yoshida, T.2    Jena, N.3    Qi, X.4    Zhang, J.5    Van Etten, R.A.6    Georgopoulos, K.7
  • 3
    • 84904207597 scopus 로고    scopus 로고
    • Epstein-Barr virus-positive polymorphous lymphoplasmacytic infiltrate of the lacrimal glands in a patient with acute lymphoblastic leukemia
    • Rashid A, Lee NG, Jakobiec FA and Freitag SK: Epstein-Barr virus-positive polymorphous lymphoplasmacytic infiltrate of the lacrimal glands in a patient with acute lymphoblastic leukemia. JAMA Ophthalmol 132: 892-894, 2014.
    • (2014) JAMA Ophthalmol , vol.132 , pp. 892-894
    • Rashid, A.1    Lee, N.G.2    Jakobiec, F.A.3    Freitag, S.K.4
  • 4
    • 84906559648 scopus 로고    scopus 로고
    • Herpes simplex virus type 2 fulminant hepatitis after umbilical cord blood transplantation for acute myeloid leukemia
    • (In Japanese)
    • Yuasa M, Ishiwata K, Sugio T, et al: Herpes simplex virus type 2 fulminant hepatitis after umbilical cord blood transplantation for acute myeloid leukemia. Rinsho Ketsueki 55: 682-686, 2014 (In Japanese).
    • (2014) Rinsho Ketsueki , vol.55 , pp. 682-686
    • Yuasa, M.1    Ishiwata, K.2    Sugio, T.3
  • 5
    • 84889042540 scopus 로고    scopus 로고
    • Ponatinib: A new tyrosine kinase inhibitor for the treatment of chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic leukemia
    • Shamroe CL and Comeau JM: Ponatinib: A new tyrosine kinase inhibitor for the treatment of chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic leukemia. Ann Pharmacother 11: 1540-1546, 2013.
    • (2013) Ann Pharmacother , vol.11 , pp. 1540-1546
    • Shamroe, C.L.1    Comeau, J.M.2
  • 7
    • 84907536932 scopus 로고    scopus 로고
    • Piperlongumine inhibits the proliferation and survival of B-cell acute lymphoblastic leukemia cell lines irrespective of glucocorticoid resistance
    • Han SS, Han S and Kamberos NL: Piperlongumine inhibits the proliferation and survival of B-cell acute lymphoblastic leukemia cell lines irrespective of glucocorticoid resistance. Biochem Biophys Res Commun 452: 669-675, 2014.
    • (2014) Biochem Biophys Res Commun , vol.452 , pp. 669-675
    • Han, S.S.1    Han, S.2    Kamberos, N.L.3
  • 8
    • 84888362641 scopus 로고    scopus 로고
    • Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells
    • Pei S, Minhajuddin M, Callahan KP, et al: Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells. J Biol Chem 288: 33542-33558, 2013.
    • (2013) J Biol Chem , vol.288 , pp. 33542-33558
    • Pei, S.1    Minhajuddin, M.2    Callahan, K.P.3
  • 10
    • 84891163325 scopus 로고    scopus 로고
    • Piperlongumine inhibits NF κB activity and attenuates aggressive growth characteristics of prostate cancer cells
    • Ginzburg S, Golovine KV, Makhov PB, Uzzo RG, Kutikov A and Kolenko VM: Piperlongumine inhibits NF κB activity and attenuates aggressive growth characteristics of prostate cancer cells. Prostate 2: 177-186, 2014.
    • (2014) Prostate , vol.2 , pp. 177-186
    • Ginzburg, S.1    Golovine, K.V.2    Makhov, P.B.3    Uzzo, R.G.4    Kutikov, A.5    Kolenko, V.M.6
  • 11
    • 84897423324 scopus 로고    scopus 로고
    • Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities
    • Liu Y, Chang Y, Yang C, et al: Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities. Nanoscale 6: 4325-4337, 2014.
    • (2014) Nanoscale , vol.6 , pp. 4325-4337
    • Liu, Y.1    Chang, Y.2    Yang, C.3
  • 12
    • 84888128272 scopus 로고    scopus 로고
    • Phosphorylated Crkl reduction levels are associated with the lowest P glycoprotein activity levels in cells from chronic myeloid leukemia patients
    • Vasconcelos FC, Nestal de Moraes G, Moellmann Coelho A and Maia RC: Phosphorylated Crkl reduction levels are associated with the lowest P glycoprotein activity levels in cells from chronic myeloid leukemia patients. Leuk Res 12: 1711-1718, 2013.
    • (2013) Leuk Res , vol.12 , pp. 1711-1718
    • Vasconcelos, F.C.1    Nestal de Moraes, G.2    Moellmann Coelho, A.3    Maia, R.C.4
  • 13
    • 84887116310 scopus 로고    scopus 로고
    • Overcoming resistance to targeted anticancer drugs
    • Doroshow JH: Overcoming resistance to targeted anticancer drugs. N Engl J Med 19: 1852-1853, 2013.
    • (2013) N Engl J Med , vol.19 , pp. 1852-1853
    • Doroshow, J.H.1
  • 14
    • 84889852625 scopus 로고    scopus 로고
    • The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance
    • Ariës IM, Hansen BR, Koch T, van den Dungen R, Evans WE, Pieters R and den Boer ML: The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance. Haematologica 12: 1905-1911, 2013.
    • (2013) Haematologica , vol.12 , pp. 1905-1911
    • Ariës, I.M.1    Hansen, B.R.2    Koch, T.3    van den Dungen, R.4    Evans, W.E.5    Pieters, R.6    den Boer, M.L.7
  • 16
    • 84884287297 scopus 로고    scopus 로고
    • Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction
    • Wang JY, Yu P, Chen S, Xing H, Chen Y, Wang M, Tang K, Tian Z, Rao Q and Wang J: Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction. Mol Oncol 5: 907-916, 2013.
    • (2013) Mol Oncol , vol.5 , pp. 907-916
    • Wang, J.Y.1    Yu, P.2    Chen, S.3    Xing, H.4    Chen, Y.5    Wang, M.6    Tang, K.7    Tian, Z.8    Rao, Q.9    Wang, J.10
  • 17
    • 84893418714 scopus 로고    scopus 로고
    • siRNA-mediated silencing of survivin inhibits proliferation and enhances etoposide chemosensitivity in acute myeloid leukemia cells
    • Karami H, Baradaran B, Esfahani A, Estiar MA, Naghavi-Behzad M, Sakhinia M and Sakhinia E: siRNA-mediated silencing of survivin inhibits proliferation and enhances etoposide chemosensitivity in acute myeloid leukemia cells. Asian Pac J Cancer Prev 12: 7719-7724, 2013.
    • (2013) Asian Pac J Cancer Prev , vol.12 , pp. 7719-7724
    • Karami, H.1    Baradaran, B.2    Esfahani, A.3    Estiar, M.A.4    Naghavi-Behzad, M.5    Sakhinia, M.6    Sakhinia, E.7
  • 19
    • 84893682835 scopus 로고    scopus 로고
    • Smac mimetic primes apoptosis resistant acute myeloid leukaemia cells for cytarabine induced cell death by triggering necroptosis
    • Chromik J, Safferthal C, Serve H and Fulda S: Smac mimetic primes apoptosis resistant acute myeloid leukaemia cells for cytarabine induced cell death by triggering necroptosis. Cancer Lett 1: 101-109, 2014.
    • (2014) Cancer Lett , vol.1 , pp. 101-109
    • Chromik, J.1    Safferthal, C.2    Serve, H.3    Fulda, S.4
  • 21
    • 84898640424 scopus 로고    scopus 로고
    • Reversal effect of ST6GAL 1 on multidrug resistance in human leukemia by regulating the PI3K/Akt pathway and the expression of P gp and MRP1
    • Ma H, Cheng L, Hao K, Li Y, Song X, Zhou H and Jia L: Reversal effect of ST6GAL 1 on multidrug resistance in human leukemia by regulating the PI3K/Akt pathway and the expression of P gp and MRP1. PLoS One 1: e85113, 2014.
    • (2014) PLoS One , vol.1
    • Ma, H.1    Cheng, L.2    Hao, K.3    Li, Y.4    Song, X.5    Zhou, H.6    Jia, L.7
  • 22
    • 84902550498 scopus 로고    scopus 로고
    • Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells
    • Shrivastava S, Kulkarni P, Thummuri D, Jeengar MK, Naidu VG, Alvala M, Redddy GB and Ramakrishna S: Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells. Apoptosis 7: 1148-1164, 2014.
    • (2014) Apoptosis , vol.7 , pp. 1148-1164
    • Shrivastava, S.1    Kulkarni, P.2    Thummuri, D.3    Jeengar, M.K.4    Naidu, V.G.5    Alvala, M.6    Redddy, G.B.7    Ramakrishna, S.8
  • 23
    • 84896397673 scopus 로고    scopus 로고
    • 3 Bromopyruvate induces apoptosis in breast cancer cells by downregulating Mcl 1 through the PI3K/Akt signaling pathway
    • Liu Z, Zhang YY, Zhang QW, Zhao SR, Wu CZ, Cheng X, Jiang CC, Jiang ZW and Liu H: 3 Bromopyruvate induces apoptosis in breast cancer cells by downregulating Mcl 1 through the PI3K/Akt signaling pathway. Anticancer Drugs 4: 447-455, 2014.
    • (2014) Anticancer Drugs , vol.4 , pp. 447-455
    • Liu, Z.1    Zhang, Y.Y.2    Zhang, Q.W.3    Zhao, S.R.4    Wu, C.Z.5    Cheng, X.6    Jiang, C.C.7    Jiang, Z.W.8    Liu, H.9
  • 24
    • 84891624292 scopus 로고    scopus 로고
    • Antileukaemic effect of PI3K mTOR inhibitors in acute myeloid leukaemia gene expression profiles reveal CDC25B expression as determinate of pharmacological effect
    • Reikvam H, Tamburini J, Skrede S, Holdhus R, Poulain L, Ersvaer E, Hatfield KJ and Bruserud Ø: Antileukaemic effect of PI3K mTOR inhibitors in acute myeloid leukaemia gene expression profiles reveal CDC25B expression as determinate of pharmacological effect. Br J Haematol 2: 200-211, 2014.
    • (2014) Br J Haematol , vol.2 , pp. 200-211
    • Reikvam, H.1    Tamburini, J.2    Skrede, S.3    Holdhus, R.4    Poulain, L.5    Ersvaer, E.6    Hatfield, K.J.7    Bruserud, Ø.8
  • 25
    • 84892999662 scopus 로고    scopus 로고
    • TrkC promotes survival and growth of leukemia cells through Akt mTOR dependent up regulation of PLK 1 and Twist 1
    • Kim MS, Kim GM, Choi YJ, Kim HJ, Kim YJ and Jin W: TrkC promotes survival and growth of leukemia cells through Akt mTOR dependent up regulation of PLK 1 and Twist 1. Mol Cells 2: 177-184, 2013.
    • (2013) Mol Cells , vol.2 , pp. 177-184
    • Kim, M.S.1    Kim, G.M.2    Choi, Y.J.3    Kim, H.J.4    Kim, Y.J.5    Jin, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.