메뉴 건너뛰기




Volumn 1383, Issue , 2015, Pages 160-168

Expanding the potential of chiral chromatography for high-throughput screening of large compound libraries by means of sub-2μm Whelk-O 1 stationary phase in supercritical fluid conditions

Author keywords

Enantioselective high throughput screening; EUHPSFC; Sub 2 m Whelk O 1; Ultra fast chiral separations

Indexed keywords

CHIRALITY; EFFLUENT TREATMENT; ENANTIOMERS; ENANTIOSELECTIVITY; LIQUID CHROMATOGRAPHY; SEPARATION; SUPERCRITICAL FLUIDS;

EID: 84922935469     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.01.042     Document Type: Article
Times cited : (50)

References (35)
  • 1
    • 0041663784 scopus 로고    scopus 로고
    • Facing chirality in the 21st century: Approaching the challenges in the pharmaceutical industry
    • Federsel H.-J. Facing chirality in the 21st century: Approaching the challenges in the pharmaceutical industry. Chirality 2003, 15:128-142.
    • (2003) Chirality , vol.15 , pp. 128-142
    • Federsel, H.-J.1
  • 2
    • 0035847272 scopus 로고    scopus 로고
    • Separations of enantiomers: needs, challenges, perspectives
    • Maier N.M., Franco P., Lindner W. Separations of enantiomers: needs, challenges, perspectives. J. Chromatogr. A 2001, 906:3-33.
    • (2001) J. Chromatogr. A , vol.906 , pp. 3-33
    • Maier, N.M.1    Franco, P.2    Lindner, W.3
  • 5
    • 0035847205 scopus 로고    scopus 로고
    • Enantioselective chromatography as a powerful alternative for the preparation of drug enantiomers
    • Francotte E.R. Enantioselective chromatography as a powerful alternative for the preparation of drug enantiomers. J. Chromatogr. A 2001, 906:379-397.
    • (2001) J. Chromatogr. A , vol.906 , pp. 379-397
    • Francotte, E.R.1
  • 6
    • 84855960441 scopus 로고    scopus 로고
    • Chiral separations: a review of current topics and trends
    • Ward T.J., Ward K.D. Chiral separations: a review of current topics and trends. Anal. Chem. 2012, 84:626-635.
    • (2012) Anal. Chem. , vol.84 , pp. 626-635
    • Ward, T.J.1    Ward, K.D.2
  • 7
    • 58149196978 scopus 로고    scopus 로고
    • Screening approaches for chiral separations
    • CRC Press, New York
    • Mangelings D., Vander Heyden Y. Screening approaches for chiral separations. Advances in Chromatography 2007, 46:175-211. CRC Press, New York.
    • (2007) Advances in Chromatography , vol.46 , pp. 175-211
    • Mangelings, D.1    Vander Heyden, Y.2
  • 8
    • 58149333480 scopus 로고    scopus 로고
    • Supercritical fluid chromatography for the 21st century
    • Taylor L.T. Supercritical fluid chromatography for the 21st century. J. Supercrit. Fluids 2009, 47:566-573.
    • (2009) J. Supercrit. Fluids , vol.47 , pp. 566-573
    • Taylor, L.T.1
  • 9
    • 84922937025 scopus 로고    scopus 로고
    • The many faces of packed column supercritical fluid chromatography-A critical review
    • Lesellier E., West C. The many faces of packed column supercritical fluid chromatography-A critical review. J. Chromatogr. A 2015, 10.1016/j.chroma.2014.12.083.
    • (2015) J. Chromatogr. A
    • Lesellier, E.1    West, C.2
  • 10
    • 84889061636 scopus 로고    scopus 로고
    • Enantioselective separations with supercritical fluids - review
    • West C. Enantioselective separations with supercritical fluids - review. Curr. Anal. Chem. 2014, 10:99-120.
    • (2014) Curr. Anal. Chem. , vol.10 , pp. 99-120
    • West, C.1
  • 11
    • 33746394108 scopus 로고    scopus 로고
    • Chiral separation strategy in polar organic solvent chromatography and performance comparison with normal-phase liquid and supercritical-fluid chromatography
    • Matthijs N., Maftouh M., Vander Heyden Y. Chiral separation strategy in polar organic solvent chromatography and performance comparison with normal-phase liquid and supercritical-fluid chromatography. J. Sep. Sci. 2006, 29:1353-1362.
    • (2006) J. Sep. Sci. , vol.29 , pp. 1353-1362
    • Matthijs, N.1    Maftouh, M.2    Vander Heyden, Y.3
  • 12
    • 23044486916 scopus 로고    scopus 로고
    • Screening approach for chiral separation of pharmaceuticals. Part III. Supercritical fluid chromatography for analysis and purification in drug discovery
    • Maftouh M., Granier-Loyaux C., Chavana E., Marini J., Pradines A., Vander Heyden Y., Picard C. Screening approach for chiral separation of pharmaceuticals. Part III. Supercritical fluid chromatography for analysis and purification in drug discovery. J. Chromatogr. A 2005, 1088:67-81.
    • (2005) J. Chromatogr. A , vol.1088 , pp. 67-81
    • Maftouh, M.1    Granier-Loyaux, C.2    Chavana, E.3    Marini, J.4    Pradines, A.5    Vander Heyden, Y.6    Picard, C.7
  • 13
    • 84870376791 scopus 로고    scopus 로고
    • Enantioselectivity of polysaccharide-based chiral stationary phase in supercritical fluid chromatography using methanol-containing carbon dioxide mobile phases
    • De Klerck K., Parewyck G., Mangelings D., Vander Heyden Y. Enantioselectivity of polysaccharide-based chiral stationary phase in supercritical fluid chromatography using methanol-containing carbon dioxide mobile phases. J. Chromatogr. A 2012, 1269:336-345.
    • (2012) J. Chromatogr. A , vol.1269 , pp. 336-345
    • De Klerck, K.1    Parewyck, G.2    Mangelings, D.3    Vander Heyden, Y.4
  • 14
    • 84908108586 scopus 로고    scopus 로고
    • Generic chiral method development in supercritical fluid chromatography and ultra-performance supercritical fluid chromatography
    • De Klerck K., Vander Heyden Y., Mangelings D. Generic chiral method development in supercritical fluid chromatography and ultra-performance supercritical fluid chromatography. J. Chromatogr. A 2014, 1363:311-322.
    • (2014) J. Chromatogr. A , vol.1363 , pp. 311-322
    • De Klerck, K.1    Vander Heyden, Y.2    Mangelings, D.3
  • 15
    • 84858800458 scopus 로고    scopus 로고
    • Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography
    • De Klerck K., Mangelings D., Clicq D., De Boever F., Vander Heyden Y. Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography. J. Chromatogr. A 2012, 1234:72-79.
    • (2012) J. Chromatogr. A , vol.1234 , pp. 72-79
    • De Klerck, K.1    Mangelings, D.2    Clicq, D.3    De Boever, F.4    Vander Heyden, Y.5
  • 16
    • 84892975533 scopus 로고    scopus 로고
    • Evaluation of non-conventional polar modifiers on immobilized chiral stationary phases for improved resolution of enantiomers by supercritical fluid chromatography
    • DaSilva J.O., Coes B., Frey L., Mergelsberg I., McClain R., Nogle L., Welch C.J. Evaluation of non-conventional polar modifiers on immobilized chiral stationary phases for improved resolution of enantiomers by supercritical fluid chromatography. J. Chromatogr. A 2014, 1328:98-103.
    • (2014) J. Chromatogr. A , vol.1328 , pp. 98-103
    • DaSilva, J.O.1    Coes, B.2    Frey, L.3    Mergelsberg, I.4    McClain, R.5    Nogle, L.6    Welch, C.J.7
  • 17
    • 84877740790 scopus 로고    scopus 로고
    • Updating a generic screening approach in sub- or supercritical chromatography for the enantioresolution of pharmaceuticals
    • De Klerck K., Tistaert C., Mangelings D., Vander Heyden Y. Updating a generic screening approach in sub- or supercritical chromatography for the enantioresolution of pharmaceuticals. J. Supercrit. Fluids 2013, 80:50-59.
    • (2013) J. Supercrit. Fluids , vol.80 , pp. 50-59
    • De Klerck, K.1    Tistaert, C.2    Mangelings, D.3    Vander Heyden, Y.4
  • 18
    • 44349182545 scopus 로고    scopus 로고
    • Chiral separations in sub- and supercritical fluids chromatography
    • Mangelings D., Vander Heyden Y. Chiral separations in sub- and supercritical fluids chromatography. J. Sep. Sci. 2008, 31:1252-1273.
    • (2008) J. Sep. Sci. , vol.31 , pp. 1252-1273
    • Mangelings, D.1    Vander Heyden, Y.2
  • 19
    • 84865078358 scopus 로고    scopus 로고
    • Supercritical fluid chromatography for the enantioseparation of pharmaceuticals
    • De Klerck K., Mangelings D., Vander Heyden Y. Supercritical fluid chromatography for the enantioseparation of pharmaceuticals. J. Pharm. Biomed. Anal. 2012, 69:77-92.
    • (2012) J. Pharm. Biomed. Anal. , vol.69 , pp. 77-92
    • De Klerck, K.1    Mangelings, D.2    Vander Heyden, Y.3
  • 20
    • 79955730754 scopus 로고    scopus 로고
    • A high throughput approach to purifying chiral molecules using 3μm analytical chiral stationary phases via supercritical fluid chromatography
    • Hamman C., Wong M., Hayes M., Gibbons P. A high throughput approach to purifying chiral molecules using 3μm analytical chiral stationary phases via supercritical fluid chromatography. J. Chromatogr. A 2011, 1218:3529-3536.
    • (2011) J. Chromatogr. A , vol.1218 , pp. 3529-3536
    • Hamman, C.1    Wong, M.2    Hayes, M.3    Gibbons, P.4
  • 22
    • 84908106118 scopus 로고    scopus 로고
    • Effect of particle size on the speed and resolution of chiral separations using supercritical fluid chromatography
    • Biba M., Regalado E.L., Wua N., Welch C.J. Effect of particle size on the speed and resolution of chiral separations using supercritical fluid chromatography. J. Chromatogr. A 2014, 1363:250-256.
    • (2014) J. Chromatogr. A , vol.1363 , pp. 250-256
    • Biba, M.1    Regalado, E.L.2    Wua, N.3    Welch, C.J.4
  • 23
    • 84908341604 scopus 로고    scopus 로고
    • Estimating optimal time for fast chromatographic separations
    • Welch C.J., Regalado E.L. Estimating optimal time for fast chromatographic separations. J. Sep. Sci. 2014, 37:2552-2558.
    • (2014) J. Sep. Sci. , vol.37 , pp. 2552-2558
    • Welch, C.J.1    Regalado, E.L.2
  • 24
    • 84881313068 scopus 로고    scopus 로고
    • The evaluation of 25 chiral stationary phases and the utilization of sub-2.0μm coated polysaccharide chiral stationary phases via supercritical fluid chromatography
    • Hamman C., Wong M., Aliagas I., Ortwine D.F., Pease J., Schmidt D.E., Victorino J. The evaluation of 25 chiral stationary phases and the utilization of sub-2.0μm coated polysaccharide chiral stationary phases via supercritical fluid chromatography. J. Chromatogr. A 2013, 1305:310-319.
    • (2013) J. Chromatogr. A , vol.1305 , pp. 310-319
    • Hamman, C.1    Wong, M.2    Aliagas, I.3    Ortwine, D.F.4    Pease, J.5    Schmidt, D.E.6    Victorino, J.7
  • 26
    • 74049095533 scopus 로고    scopus 로고
    • Transition from enantioselective high performance to ultra-high performance liquid chromatography: A case study of a brush-type chiral stationary phase based on sub-5-micron to sub-2-micron silica particles
    • Cancelliere G., Ciogli A., D'Acquarica I., Gasparrini F., Kocergin J., Misiti D., Pierini M., Ritchie H., Simone P., Villani C. Transition from enantioselective high performance to ultra-high performance liquid chromatography: A case study of a brush-type chiral stationary phase based on sub-5-micron to sub-2-micron silica particles. J. Chromatogr. A 2010, 1217:990-999.
    • (2010) J. Chromatogr. A , vol.1217 , pp. 990-999
    • Cancelliere, G.1    Ciogli, A.2    D'Acquarica, I.3    Gasparrini, F.4    Kocergin, J.5    Misiti, D.6    Pierini, M.7    Ritchie, H.8    Simone, P.9    Villani, C.10
  • 27
  • 29
    • 0031561759 scopus 로고    scopus 로고
    • Some recent high-performance liquid chromatography separations of the enantiomers of pharmaceuticals and other compounds using the Whelk-O 1 chiral stationary phase
    • Welch C.J., Szczerba T., Perrin S.R. Some recent high-performance liquid chromatography separations of the enantiomers of pharmaceuticals and other compounds using the Whelk-O 1 chiral stationary phase. J. Chromatogr. A 1997, 758:93-98.
    • (1997) J. Chromatogr. A , vol.758 , pp. 93-98
    • Welch, C.J.1    Szczerba, T.2    Perrin, S.R.3
  • 30
    • 84868375132 scopus 로고    scopus 로고
    • Comparison of ultra-high performance supercritical fluid chromatography and ultra-high performance liquid chromatography for the analysis of pharmaceutical compounds
    • Grand-Guillaume Perrenoud A., Veuthey J.-L., Guillaume D. Comparison of ultra-high performance supercritical fluid chromatography and ultra-high performance liquid chromatography for the analysis of pharmaceutical compounds. J. Chromatogr. A 2012, 1266:158-167.
    • (2012) J. Chromatogr. A , vol.1266 , pp. 158-167
    • Grand-Guillaume Perrenoud, A.1    Veuthey, J.-L.2    Guillaume, D.3
  • 31
    • 0026720612 scopus 로고
    • Design, synthesis, and evaluation of an improved enantioselective naproxen selector
    • Pirkle W.H., Welch C.J., Lamm B. Design, synthesis, and evaluation of an improved enantioselective naproxen selector. J. Org. Chem. 1992, 57:3854-3860.
    • (1992) J. Org. Chem. , vol.57 , pp. 3854-3860
    • Pirkle, W.H.1    Welch, C.J.2    Lamm, B.3
  • 32
    • 0026651356 scopus 로고
    • An improved chiral stationary phase for the chromatographic separation of underivatized naproxen enantiomers
    • Pirkle W.H., Welch C.J. An improved chiral stationary phase for the chromatographic separation of underivatized naproxen enantiomers. J. Liq. Chromatogr. 1992, 15:1947-1955.
    • (1992) J. Liq. Chromatogr. , vol.15 , pp. 1947-1955
    • Pirkle, W.H.1    Welch, C.J.2
  • 33
    • 84889602021 scopus 로고    scopus 로고
    • Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis
    • Fekete S., Kohler I., Rudaz S., Guillarme D. Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis. J. Pharm. Biomed. Anal. 2014, 87:105-119.
    • (2014) J. Pharm. Biomed. Anal. , vol.87 , pp. 105-119
    • Fekete, S.1    Kohler, I.2    Rudaz, S.3    Guillarme, D.4
  • 34
    • 84985205399 scopus 로고
    • Density of methanol-carbon dioxide mixtures at three temperatures: Comparison with vapor-liquid equilibria measurements and results obtained from chromatography
    • Berger T.A. Density of methanol-carbon dioxide mixtures at three temperatures: Comparison with vapor-liquid equilibria measurements and results obtained from chromatography. J. High Resolut. Chromatogr. 1991, 14:312-316.
    • (1991) J. High Resolut. Chromatogr. , vol.14 , pp. 312-316
    • Berger, T.A.1
  • 35
    • 0031077722 scopus 로고    scopus 로고
    • Effect of mobile phase additives in packed-column subcritical and supercritical fluid chromatography
    • Blackwell J.A., Stringham R.W., Weckwerth J.D. Effect of mobile phase additives in packed-column subcritical and supercritical fluid chromatography. Anal. Chem. 1997, 69:409-415.
    • (1997) Anal. Chem. , vol.69 , pp. 409-415
    • Blackwell, J.A.1    Stringham, R.W.2    Weckwerth, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.