Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography

Journal of Chromatography A

Volumn 1234, Issue , 2012, Pages 72-79

  De Klerck, Katrijn ^a   Mangelings, Debby ^a   Clicq, David ^b   De Boever, Filip ^b   Vander Heyden, Yvan ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UCB PHARMA   (Belgium)

Author keywords

Chiral separations; Isopropylamine; Methanol containing mobile phase; Mobile phase additives; SFC; Trifluoroacetic acid

Indexed keywords

CHIRAL SEPARATIONS; ISOPROPYLAMINE; METHANOL-CONTAINING MOBILE PHASE; MOBILE PHASE ADDITIVES; SFC; TRIFLUOROACETIC ACIDS;

CELLULOSE; CHIRALITY; DIAGNOSIS; ENANTIOSELECTIVITY; GAS CHROMATOGRAPHY; METHANOL;

ADDITIVES;

ACEBUTOLOL; ACENOCOUMAROL; ALPRENOLOL; AMINE; ATENOLOL; ATROPINE; BETAXOLOL; BISOPROLOL; BOPINDOLOL; BUPRANOLOL; CARAZOLOL; CARBINOXAMINE; CARVEDILOL; CHLORPHENIRAMINE; DIMETINDENE; EPHEDRINE; ESMOLOL; FENOPROFEN; FLURBIPROFEN; FOLINIC ACID; HEXOBARBITAL; IBUPROFEN; ISOPROPYLAMINE; KETOPROFEN; LABETALOL; MEPINDOLOL; METHANOL; POLYSACCHARIDE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CHIRALITY; COMPLEX FORMATION; DRUG ANALYSIS; ENANTIOSELECTIVITY; PHASE SEPARATION; PRIORITY JOURNAL; SUPERCRITICAL FLUID CHROMATOGRAPHY;

AMYLOSE; CELLULOSE; CHROMATOGRAPHY, SUPERCRITICAL FLUID; HYDROGEN-ION CONCENTRATION; METHANOL; PHARMACEUTICAL PREPARATIONS; PROPYLAMINES; STEREOISOMERISM; TRIFLUOROACETIC ACID;

EID: 84858800458     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.11.023     Document Type: Article

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