Systemic inflammation in xenograft recipients precedes activation of coagulation

Xenotransplantation

Volumn 22, Issue 1, 2015, Pages 32-47

  Ezzelarab, Mohamed B ^a   Ekser, Burcin ^b   Azimzadeh, Agnes ^c   Lin, Chih Che ^d   Zhao, Yuming ^c   Rodriguez, Rachael ^c   Echeverri, Gabriel J ^e   Iwase, Hayato ^a   Long, Cassandra ^a   Hara, Hidetaka ^a   Ayares, David ^f   Pierson, Richard N ^c   Thomson, Angus W ^a,g   Cooper, David K ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF CATANIA   (Italy)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^e FUNDACIÓN VALLE DEL LILI   (Colombia)

^f REVIVICOR INC   (United States)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

C reactive protein; coagulation; dendritic cells; inflammation; interleukin 6; monocytes; pig; primate; xenotransplantation

Indexed keywords

C REACTIVE PROTEIN; CD14 ANTIGEN; CD40 ANTIGEN; FIBRINOGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; MEMBRANE COFACTOR PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; THROMBIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; ALPHA-1,3-GALACTOSYLTRANSFERASE 1, PORCINE; BLOOD CLOTTING FACTOR; CD46 PROTEIN, HUMAN; CHEMOKINE; CYTOKINE; GALACTOSYLTRANSFERASE; IMMUNOSUPPRESSIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY GRAFT; ARTICLE; BABOON; BLOOD CLOTTING; DENDRITIC CELL; GALACTOSYLTRANSFERASE GENE KNOCKOUT PIG; GRAFT RECIPIENT; HEART GRAFT; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; KIDNEY GRAFT; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOGRAFT; XENOTRANSPLANTATION; ANIMAL; ARTERY; BIOSYNTHESIS; BLOOD; DEFICIENCY; GENE INACTIVATION; GENETICS; HEART TRANSPLANTATION; HUMAN; IMMUNOLOGY; KIDNEY TRANSPLANTATION; PATHOLOGY; PIG; POSTOPERATIVE COMPLICATIONS; TRANSGENIC ANIMAL; TRANSPLANTATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD46; ARTERIES; BLOOD COAGULATION; BLOOD COAGULATION FACTORS; C-REACTIVE PROTEIN; CHEMOKINES; CYTOKINES; DENDRITIC CELLS; GALACTOSYLTRANSFERASES; GENE KNOCKOUT TECHNIQUES; HEART TRANSPLANTATION; HETEROGRAFTS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; KIDNEY TRANSPLANTATION; MONOCYTES; PAPIO; POSTOPERATIVE COMPLICATIONS; RNA, MESSENGER; SUS SCROFA; SWINE; THROMBOPLASTIN;

EID: 84922743746     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12133     Document Type: Article

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