C5a and TNF-α up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome

Journal of Immunology

Volumn 180, Issue 11, 2008, Pages 7368-7375

  Kambas, Konstantinos ^a   Markiewski, Maciej M ^b   Pneumatikos, Ioannis A ^a   Rafail, Stavros S ^a   Theodorou, Vassiliki ^a   Konstantonis, Dimitrios ^a   Kourtzelis, Ioannis ^a   Doumas, Michael N ^a   Magotti, Paola ^b   DeAngelis, Robert A ^b   Lambris, John D ^b   Ritis, Konstantinos D ^a,c  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NONE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN C5A; PROTEIN DERIVATIVE; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; COMPLEMENT COMPONENT C5A; CYTOKINE; FIBRIN;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; HUMAN; LUNG ALVEOLUS; LUNG LAVAGE; NEUTROPHIL COUNT; ORGAN DONOR; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ADULT; AGED; CYTOLOGY; IMMUNOLOGY; METABOLISM; MIDDLE AGED; NEUTROPHIL;

ADULT; AGED; BRONCHOALVEOLAR LAVAGE FLUID; COMPLEMENT C5A; CYTOKINES; FIBRIN; HUMANS; MIDDLE AGED; NEUTROPHILS; RESPIRATORY DISTRESS SYNDROME, ADULT; THROMBOPLASTIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 47249121697     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.11.7368     Document Type: Article

References (50)

1. Frutos-Vivar, F., N. Nin, and A. Esteban. 2004. Epidemiology of acute lung injury and acute respiratory distress syndrome. Curr. Opin. Crit. Care 10: 1-6.
2. The Acute Respiratory Distress Syndrome Network. 2000. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N. Engl. J. Med. 342: 1301-1308.
3. Idell, S. 1994. Extravascular coagulation and fibrin deposition in acute lung injury. New Horiz. 2: 566-574.
4. Ware, L. B., and M. A. Matthay. 2000. The acute respiratory distress syndrome. N. Engl. J. Med 342: 1334-1349.
5. Günther, A., P. Mosavi, S. Heinemann, C. Ruppert, H. Muth, P. Markart, F. Grimminger, D. Walmrath, B. Temmesfeld-Wollbrück, and W. Seeger. 2000. Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia: comparison with the acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 161: 454-462.
6. Nuckton, T. J., J. A. Alonso, R. H. Kallet, B. M. Daniel, J. F. Pittet, M. D. Eisner, and M. A. Matthay. 2002. Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N. Engl. J. Med. 346: 1281-1286.
7. Idell, S., K. K. James, E. G. Levin, B. S. Schwartz, N. Manchanda, R. J. Maunder, T. R. Martin, J. McLarty, and D. S. Fair. 1989. Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome. J. Clin. Invest. 84: 695-705.
8. Giesen, P., U. Rauch, B. Bohrmann, D. Kling, M. Roqué, J. T. Fallon, J. J. Badimon, J. Himber, M. A. Riederer, and Y. Nemerson. 1999. Blood-borne tissue factor: another view of thrombosis. Proc. Natl. Acad. Sci. USA 96: 2311-2315.
9. Szotowski, B., S. Antoniak, W. Poller, H. P. Schultheiss, and U. Rauch. 2005. Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines. Circ. Res. 96: 1233-1239.
10. Abraham, E. 2003. Neutrophils and acute lung injury. Crit. Care Med. 31: S195-S199.
11. Reutershan, J., and K. Ley. 2004. Bench-to-bedside review: acute respiratory distress syndrome: how neutrophils migrate into the lung. Crit. Care 8: 453-461.
12. Reutershan, J., A. Basit, E. V. Galkina, and K. Ley. 2005. Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury. Am. J. Physiol 289: L807-L815.
13. Bachofen, M., and E. R. Weibel. 1982. Structural alterations of lung parenchyma in the adult respiratory distress syndrome. Clin. Chest Med. 3: 35-56.
14. Meyrik, B. 1986. Pathology of the adult respiratory distress syndrome. Crit. Care Clin. 2: 405-429.
15. Ritis, K., M. Doumas, D. Mastellos, A. Micheli, S. Giaglis, P. Magotti, S. Rafail, G. Kartalis, P. Sideras, and J. D. Lambris. 2006. A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways. J. Immunol. 177: 4794-4802.
16. Weiland, J. E., W. B. Davis, J. F. Holter, J. R. Mohammed, P. M. Dorinsky, and J. E. Gadek. 1986. Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance. Am. Rev. Respir. Dis. 133: 218-225.
17. Kinoshita, M., H. Mochizuki, and S. Ono. 1999. Pulmonary neutrophil accumulation following human endotoxemia. Chest 116: 1709-1715.
18. Robbins, R. A., W. D. Russ, J. K. Rasmussen, and M. M. Clayton. 1987. Activation of the complement system in the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 135: 651-658.
19. Huber-Lang, M., J. V. Sarma, F. S. Zetoune, D. Rittirsch, T. A. Neff, S. R. McGuire, J. D. Lambris, R. L. Warner, M. A. Flierl, L. M. Hoesel, et al. 2006. Generation of C5a in the absence of C3: a new complement activation pathway. Nat. Med. 12: 682-687.
20. Bernard, G., A. Artigas, K. Brigham, J. Carlet, K. Falke, L. Hudson, M. Lamy, J. R. Legall, A. Morris, and R. Spragg. 1994. The American-European Consensus Conference on ARDS. Am. J. Respir. Crit. Care Med. 149: 818-824.
21. Nakos, G., J. Pneumatikos, I. Tsangaris, C. Tellis, and M. Lekka. 1997. Proteins and phospholipids in BAL from patients with hydrostatic pulmonary edema. Am. J. Respir. Crit. Care Med. 155: 945-951.
22. Rothberger, H., T. S. Zimmerman, and J. H. Vaughan. 1978. Increased production and expression of tissue thromboplastin-like procoagulant activity in vitro by allogeneically stimulated human leukocytes. J. Clin. Invest. 62: 649-655.
23. Schwartz, B. S., and T. S. Edgington. 1981. Immune complex-induced human monocyte procoagulant activity: I. A rapid unidirectional lymphocyte-instructed pathway. J. Exp. Med. 154: 892-906.
24. Rothberger, H., T. S. Zimmerman, H. L. Spiegelberg, and J. H. Vaughan. 1977. Leukocyte procoagulant activity: enhancement of production in vitro by IgG and antigen-antibody complexes. J. Clin. Invest. 59: 549-557.
25. Ames, R., D. Lee, J. Foley, A. J. Jurewicz, M. A. Tornetta, W. Bautsch, B. Settmacher, A. Klos, K. F. Erhard, R. D. Cousins, et al. 2001. Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates anti-inflammatory activity in animal models. J. Immunol. 166: 6341-6348.
26. Mastellos, D., J. Papadimitriou, S. Franchini, P. A. Tsonis, and J. D. Lambris. 2001. A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration. J. Immunol. 166: 2479-2488.
27. Bogdanov, V., V. Balasubramanian, J. Hathcock, O. Vele, M. Lieb, and Y. Nemerson. 2003. Alternatively spliced human tissue factor: a circulation soluble, thrombogenic protein. Nat. Med. 9: 458-462.
28. Szotowski, B., P. Goldin-Lang, S. Antoniak, V. Y. Bogdanov, D. Pathirana, M. Pauschinger, A. Dörner, U. Kuehl, S. Coupland, Y. Nemerson, et al. 2005. Alteration in myocardial tissue factor expression and cellular localization in dilated cardiomyopathy. J. Am. Coll. Cardiol. 45: 1081-1089.
29. T method. Methods 25: 402-408.
30. Cordell, J., B. Fallini, W. Erber, A. K. Ghosh, Z. Abdulaziz, S. MacDonald, K. A. Pulford, H. Stein, and D. Y. Mason. 1984. Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal antialkaline phosphatase (APAAP complexes). J. Histochem. Cytochem. 32: 219-229.
31. Markiewski, M. M., B. Nilsson, K. N. Ekdahl, T. E. Mollnes, and J. D. Lambris. 2007. Complement and coagulation: strangers or partners in crime? Trends Immunol. 28: 184-192.
32. Redecha, P., R. Tilley, M. Tencati, J. E. Salmon, D. Kirchhofer, N. Mackman, and G. Girardi. 2007. Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody-induced fetal injury. Blood 110: 2423-2431.
33. Bhatia, M., and S. Moochhala. 2004. Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome. J. Pathol. 202: 145-156.
34. Cirelli, R. A., L. A. Carey, J. K. Fisher, D. L. Rosolia, T. H. Elsasser, T. J. Caperna, M. H. Gee, and K. H. Albertine. 1995. Endotoxin infusion in anesthetized sheep associated with intrapulmonary sequestration of leukocytes that immunohistochemically express tumor necrosis factor-α. J. Leukocyte Biol. 57: 820-826.
35. Ognibene, F. P., S. E. Martin, M. M. Parker, T. Schlesinger, P. Roach, C. Burch, J. H. Shelhamer, and J. E. Parrillo. 1986. Adult respiratory distress syndrome in patients with severe neulropenia. N. Engl. J. Med. 315: 547-551.
36. Azoulay, E., M. Darmon, C. Delclaux, F. Fieux, C. Boenstain, D. Moreau, H. Attalah, J. R. Le Gall, and B. Schlemmer. 2002. Deterioration of previous acute lung injury during neutropenia recovery. Crit. Care Med. 30: 781-786.
37. Doerschuk, C. M., W. M. Quinlan, N. A. Doyle, D. C. Bullard, D. Vestweber, M. L. Jones, F. Takei, P. A. Ward, and A. L. Beaudet. 1996. The role of P-selectin and ICAM-1 in acute lung injury as determined using blocking antibodies and mutant mice. J. Immunol. 157: 4609-4614.
38. Heflin, A. C, Jr., and K. L. Brighman. 1981. Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia. J. Clin. Invest. 68: 1253-1260.
39. Till, G. O., K. T. Johnson, R. Kunkel, and P. A. Ward. 1982. Intravascular activation of complement and acute lung injury: dependency on neutrophils and toxic oxygen intermediates. J. Clin. Invest. 69: 1126-1135.
40. Markiewski, M. M., and J. D. Lambris. 2007. The role of complement in inflammatory diseases from behind the scenes into the spotlight. Am. J. Pathol. 171: 715-727.
41. Harkin, D. W., C. D. Marron, R. P. Rother, A. Romaschin, B. B. Rubin, and T. F. Lindsay. 2005. C5 complement inhibition attenuates shock and acute lung injury in an experimental model of ruptured abdominal aortic aneurysm. Br. J. Surg. 92: 1227-1234.
42. Mulligan, M. S., E. Schmid, B. Beck-Schimmer, G. O. Till, H. P. Friedl, R. B. Brauer, T. E. Hugli, M. Miyasaka, R. L. Warner, K. J. Johnson, and P. A. Ward. 1996. Requirement and role of C5a in acute lung inflammatory injury in rats. J. Clin. Invest. 98: 503-512.
43. Suter, P. M., S. Suter, E. Girardin, P. Roux-Lombard, G. E. Grau, and J. M. Dayer. 1992. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am. Rev. Respir. Dis. 145: 1016-1022.
44. Meduri, G. U., G. Kohler, S. Headley, E. Tolley, F. Stentz, and A. Postlethwaite. 1995. Inflammatory cytokines in the BAL of patients with ARDS: persistent elevation over time predicts poor outcome. Chest 108: 1303-1314.
45. Schnyder-Candrian, S., V. Quesniaux, F. Padova, I. Maillet, N. Noulin, I. Couillin, R. Moser, F. Erard, B. B. Vargaftig, B. Ryffel, and B. Schnyder. 2005. Dual effects of p38 MAPK on TNF-dependent bronchoconstriction and TNF-independent neutrophil recruitment in lipopolysaccharide-induced acute respiratory distress syndrome. J. Immunol. 175: 262-269.
46. Scapini, P., J. A. Lapinet-Vera, S. Gasperini, F. Calzetti, F. Bazzoni, and M. A. Cassatella. 2000. The neutrophil as a cellular source of chemokines. Immunol. Rev. 177: 195-203.
47. He, X., B. Han, M. Mura, L. Li, M. Cypel, A. Soderman, K. Picha, J. Yang, and M. Liu. 2008. Anti-human tissue factor antibody ameliorated intestinal ischemia reperfusion-induced acute ling injury in human tissue factor knock in-mice. PLoS ONE 3: e1527.
48. Oikonomou, N., V. Harokopos, J. Zalevsky, C. Valavanis, A. Kotanidou, D. E. Szymkowski, G. Kollias, and V. Aidinis. 2006. Soluble TNF mediates the transition from pulmonary inflammation to fibrosis. PLoS ONE 1: e108.
49. Azoulay, E., S. Herigault, M. Levame, L. Brochard, B. Schlemmer, A. Harf, and C. Delclaux. 2003. Effect of granulocyte colony-stimulating factor on bleomycin-induced acute lung injury and pulmonary fibrosis. Crit. Care Med. 31: 1442-1448.
50. Guery, B. P., D. A. Welsh, N. B. Viget, L. Robriquet, P. Fialdes, C. M. Mason, G. Beaucaire, G. J. Bagby, and R. Neviere. 2003. Ventilation-induced lung injury is associated with an increase in gut permeability. Shock 19: 559-563.