A Genetic Strategy to Measure Circulating Drosophila Insulin Reveals Genes Regulating Insulin Production and Secretion

PLoS Genetics

Volumn 10, Issue 8, 2014, Pages

  Park, Sangbin ^a   Alfa, Ronald W ^a   Topper, Sydni M ^a   Kim, Grace E S ^a   Kockel, Lutz ^a   Kim, Seung K ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN LIKE PEPTIDE 2; INSULIN RECEPTOR; PEPTIDE; UNCLASSIFIED DRUG; BCL11A PROTEIN, HUMAN; CARRIER PROTEIN; DROSOPHILA PROTEIN; GLIS3 PROTEIN, HUMAN; ILP2 PROTEIN, DROSOPHILA; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

ADULT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; GENE SILENCING; GENETIC ASSOCIATION; HAPLOINSUFFICIENCY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORTHOLOGY; PEPTIDE SYNTHESIS; PHENOTYPE; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; ANIMAL; BIOSYNTHESIS; DIET RESTRICTION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; INSULIN RESISTANCE; METABOLISM; PATHOLOGY; SECRETION (PROCESS);

ANIMALS; CARRIER PROTEINS; DIABETES MELLITUS, TYPE 2; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FASTING; GENE KNOCKDOWN TECHNIQUES; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INSULIN; INSULIN RESISTANCE; NUCLEAR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84922736375     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004555     Document Type: Article

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