Assessment of an in vitro model of pulmonary barrier to study the translocation of nanoparticles

Toxicology Reports

Volumn 1, Issue , 2014, Pages 157-171

  Dekali, Samir ^a,b   Gamez, Christelle ^a   Kortulewski, Thierry ^c   Blazy, Kelly ^a   Rat, Patrice ^b   Lacroix, Ghislaine ^a  

^a INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

^b FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^c INSTITUT DE RADIOBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

Author keywords

Alveolo capillary barrier; Calu 3; HPMEC ST1.6R; Nanoparticles; Polystyrene; THP 1

Indexed keywords

NANOPARTICLE; OCCLUDIN; UVOMORULIN; VASCULAR ENDOTHELIAL CADHERIN;

ARTICLE; CELL VIABILITY ASSAY; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYTOTOXICITY; ELECTRIC RESISTANCE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PARTICLE SIZE; PERMEABILITY BARRIER; PROTEIN EXPRESSION; PULMONARY BARRIER; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TRANSEPITHELIAL ELECTRICAL RESISTANCE; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

EID: 84922697752     PISSN: 22147500     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxrep.2014.03.003     Document Type: Article

References (47)

1. Tetley T.D. Health effects of nanomaterials. Biochem. Soc. Trans. 2007, 35:527-531.
2. Oberdorster G., Oberdorster E., Oberdorster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect. 2005, 113:823-839.
3. Kreyling W.G., Semmler-Behnke M., Takenaka S., Moller W. Differences in the biokinetics of inhaled nano- versus micrometer-sized particles. Acc. Chem. Res. 2013, 46:714-722.
4. Kreyling W.G., Hirn S., Moller W., Schleh C., Wenk A., et al. Air-blood barrier translocation of tracheally instilled gold nanoparticles inversely depends on particle size. ACS Nano 2014, 8:222-233.
5. Gehr P., Bachofen M., Weibel E.R. The normal human lung: ultrastructure and morphometric estimation of diffusion capacity. Respir. Physiol. 1978, 32:121-140.
6. Crapo J.D., Barry B.E., Gehr P., Bachofen M., Weibel E.R. Cell number and cell characteristics of the normal human lung. Am. Rev. Respir. Dis. 1982, 126:332-337.
7. Fehrenbach H. Alveolar epithelial type II cell: defender of the alveolus revisited. Respir. Res. 2001, 2:33-46.
8. Hawgood S., Clements J.A. Pulmonary surfactant and its apoproteins. J. Clin. Invest. 1990, 86:1-6.
9. Clements J.A. Functions of the alveolar lining. Am. Rev. Respir. Dis. 1977, 115:67-71.
10. Lambrecht B.N. Alveolar macrophage in the driver's seat. Immunity 2006, 24:366-368.
11. Schneeberger-Keeley E.E., Karnovsky M.J. The ultrastructural basis of alveolar-capillary membrane permeability to peroxidase used as a tracer. J. Cell Biol. 1968, 37:781-793.
12. Lehmann A.D., Daum N., Bur M., Lehr C.M., Gehr P., et al. An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier. Eur. J. Pharm. Biopharm. 2010, 77:398-406.
13. Klein S.G., Serchi T., Hoffmann L., Blomeke B., Gutleb A.C. An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung. Part. Fibre Toxicol. 2013, 10:31.
14. Napierska D., Thomassen L.C., Vanaudenaerde B., Luyts K., Lison D., et al. Cytokine production by co-cultures exposed to monodisperse amorphous silica nanoparticles: the role of size and surface area. Toxicol. Lett. 2012, 211:98-104.
15. Alfaro-Moreno E., Nawrot T.S., Vanaudenaerde B.M., Hoylaerts M.F., Vanoirbeek J.A., et al. Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10. Eur. Respir. J. 2008, 32:1184-1194.
16. Rothen-Rutishauser B.M., Kiama S.G., Gehr P. A three-dimensional cellular model of the human respiratory tract to study the interaction with particles. Am. J. Respir. Cell Mol. Biol. 2005, 32:281-289.
17. Rothen-Rutishauser B., Muhlfeld C., Blank F., Musso C., Gehr P. Translocation of particles and inflammatory responses after exposure to fine particles and nanoparticles in an epithelial airway model. Part. Fibre Toxicol. 2007, 4:9.
18. Rothen-Rutishauser B., Blank F., Muhlfeld C., Gehr P. In vitro models of the human epithelial airway barrier to study the toxic potential of particulate matter. Expert Opin. Drug Metab. Toxicol. 2008, 4:1075-1089.
19. Hermanns M.I., Unger R.E., Kehe K., Peters K., Kirkpatrick C.J. Lung epithelial cell lines in coculture with human pulmonary microvascular endothelial cells: development of an alveolo-capillary barrier in vitro. Lab. Invest. 2004, 84:736-752.
20. Gazdar A.F., Linnoila R.I., Kurita Y., Oie H.K., Mulshine J.L., et al. Peripheral airway cell differentiation in human lung cancer cell lines. Cancer Res. 1990, 50:5481-5487.
21. Hermanns M.I., Kasper J., Dubruel P., Pohl C., Uboldi C., et al. An impaired alveolar-capillary barrier in vitro: effect of proinflammatory cytokines and consequences on nanocarrier interaction. J. R. Soc. Interface 2009, 7(Suppl. 1):S41-S54.
22. Stentebjerg-Andersen A., Notlevsen I.V., Brodin B., Nielsen C.U. Calu-3 cells grown under AIC and LCC conditions: implications for dipeptide uptake and transepithelial transport of substances. Eur. J. Pharm. Biopharm. 2011, 78:19-26.
23. Krump-Konvalinkova V., Bittinger F., Unger R.E., Peters K., Lehr H.A., et al. Generation of human pulmonary microvascular endothelial cell lines. Lab. Invest. 2001, 81:1717-1727.
24. Lanone S., Rogerieux F., Geys J., Dupont A., Maillot-Marechal E., et al. Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines. Part. Fibre Toxicol. 2009, 6:14.
25. Legendre A., Froment P., Desmots S., Lecomte A., Habert R., et al. An engineered 3D blood-testis barrier model for the assessment of reproductive toxicity potential. Biomaterials 2010, 31:4492-4505.
26. Lemieux M., Bouchard F., Gosselin P., Paquin J., Mateescu M.A. The NCI-N87 cell line as a gastric epithelial barrier model for drug permeability assay. Biochem. Biophys. Res. Commun. 2011, 412:429-434.
27. Dekali S., Divetain A., Kortulewski T., Vanbaelinghem J., Gamez C., et al. Cell cooperation and role of the P2X7 receptor in pulmonary inflammation induced by nanoparticles. Nanotoxicology 2012.
28. Godfrey R.W. Human airway epithelial tight junctions. Microsc. Res. Tech. 1997, 38:488-499.
29. Elbert K.J., Schafer U.F., Schafers H.J., Kim K.J., Lee V.H., et al. Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies. Pharm. Res. 1999, 16:601-608.
30. Saitou M., Ando-Akatsuka Y., Itoh M., Furuse M., Inazawa J., et al. Mammalian occludin in epithelial cells: its expression and subcellular distribution. Eur. J. Cell Biol. 1997, 73:222-231.
31. Cavanaugh K.J., Oswari J., Margulies S.S. Role of stretch on tight junction structure in alveolar epithelial cells. Am. J. Respir. Cell Mol. Biol. 2001, 25:584-591.
32. Wan H., Winton H.L., Soeller C., Stewart G.A., Thompson P.J., et al. Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o. Eur. Respir. J. 2000, 15:1058-1068.
33. Santos M.I., Fuchs S., Gomes M.E., Unger R.E., Reis R.L., et al. Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering. Biomaterials 2007, 28:240-248.
34. Sapin C., Baricault L., Trugnan G. PKC-dependent long-term effect of PMA on protein cell surface expression in Caco-2 cells. Exp. Cell Res. 1997, 231:308-318.
35. Frohlich E., Meindl C., Roblegg E., Ebner B., Absenger M., et al. Action of polystyrene nanoparticles of different sizes on lysosomal function and integrity. Part. Fibre Toxicol. 2012, 9:26.
36. Frohlich E., Samberger C., Kueznik T., Absenger M., Roblegg E., et al. Cytotoxicity of nanoparticles independent from oxidative stress. J. Toxicol. Sci. 2009, 34:363-375.
37. Ruenraroengsak P., Novak P., Berhanu D., Thorley A.J., Valsami-Jones E., et al. Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles. Nanotoxicology 2012, 6:94-108.
38. Xia T., Kovochich M., Brant J., Hotze M., Sempf J., et al. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett. 2006, 6:1794-1807.
39. Kasper J., Hermanns M.I., Bantz C., Maskos M., Stauber R., et al. Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: comparison with conventional monocultures. Part. Fibre Toxicol. 2011, 8:6.
40. Jantzen K., Roursgaard M., Desler C., Loft S., Rasmussen L.J., et al. Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages. Mutagenesis 2012.
41. Lehmann A.D., Blank F., Baum O., Gehr P., Rothen-Rutishauser B.M. Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro. Part. Fibre Toxicol. 2009, 6:26.
42. Geys J., De Vos R., Nemery B., Hoet P.H. In vitro translocation of quantum dots and influence of oxidative stress. Am. J. Physiol. Lung Cell Mol. Physiol. 2009, 297:L903-L911.
43. Huh D., Matthews B.D., Mammoto A., Montoya-Zavala M., Hsin H.Y., et al. Reconstituting organ-level lung functions on a chip. Science 2010, 328:1662-1668.
44. Blank F., Rothen-Rutishauser B., Gehr P. Dendritic cells and macrophages form a transepithelial network against foreign particulate antigens. Am. J. Respir. Cell Mol. Biol. 2007, 36:669-677.
45. Geys J., Coenegrachts L., Vercammen J., Engelborghs Y., Nemmar A., et al. In vitro study of the pulmonary translocation of nanoparticles: a preliminary study. Toxicol. Lett. 2006, 160:218-226.
46. Yacobi N.R., Demaio L., Xie J., Hamm-Alvarez S.F., Borok Z., et al. Polystyrene nanoparticle trafficking across alveolar epithelium. Nanomedicine 2008, 4:139-145.
47. Halamoda Kenzaoui B., Angeloni S., Overstolz T., Niedermann P., Chapuis Bernasconi C., et al. Transfer of ultrasmall iron oxide nanoparticles from human brain-derived endothelial cells to human glioblastoma cells. ACS Appl. Mater. Interfaces 2013, 5:3581-3586.