Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro

Particle and Fibre Toxicology

Volumn 6, Issue , 2009, Pages

  Lehmann, Andrea D ^a   Blank, Fabian ^b   Baum, Oliver ^a   Gehr, Peter ^a   Rothen Rutishauser, Barbara M ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77952824546     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-6-26     Document Type: Article

References (54)

1. Pope CA, Thun MJ, Namboodiri MM, Dockery DW, Evans JS, Speizer FE, et al. Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults. Am J Respir Crit Care Med 1995, 151:669-674.
2. Peters A, Wichmann HE, Tuch T, Heinrich J, Heyder J. Respiratory effects are associated with the number of ultrafine particles. Am J Respir Crit Care Med 1997, 155:1376-1383.
3. Schulz H, Harder V, Ibald-Mulli A, Khandoga A, Koenig W, Krombach F, et al. Cardiovascular effects of fine and ultrafine particles. J Aerosol Med 2005, 18:1-22. 10.1089/jam.2005.18.1, 15741770.
4. Ruckerl R, Phipps RP, Schneider A, Frampton M, Cyrys J, Oberdorster G, et al. Ultrafine particles and platelet activation in patients with coronary heart disease--results from a prospective panel study. Part Fibre Toxicol 2007, 4:1. 10.1186/1743-8977-4-1, 1790903, 17241467.
5. Bayram H, Devalia JL, Sapsford RJ, Ohtoshi T, Miyabara Y, Sagai M, et al. The effect of diesel exhaust particles on cell function and release of inflammatory mediators from human bronchial epithelial cells in vitro. Am J Respir Cell Mol Biol 1998, 18:441-448.
6. Westerholm RM, Jocob A, Li H. Chemical and biological characterization of particulate, semivolantile and gaz-phase-asssociated compounds in diluted heavy-duty diesel exhaust: a comparison of three different semivolatile-phase samplers. environ sci technol 1991, 25:332-338.
7. Brooks A, Wolf R, Royer R, Clark C, Sanchez A, McClellan RO. Deposition and biological availability of diesel particles and their associated mutagenic chemicals. Environ Int 1987, 5:263-267.
8. Boland S, Baeza-Squiban A, Fournier T, Houcine O, Gendron MC, Chevrier M, et al. Diesel exhaust particles are taken up by human airway epithelial cells in vitro and alter cytokine production. Am J Physiol 1999, 276:L604-L613.
9. Boland S, Baeza-Squiban A, Bonvallot V, Houcine O, Pain C, Meyer M, et al. Similar cellular effects induced by diesel exhaust particles from a representative diesel vehicle recovered from filters and Standard Reference Material 1650. Toxicol In Vitro 2001, 15:379-385. 10.1016/S0887-2333(01)00040-6, 11566567.
10. Riedl M, Diaz-Sanchez D. Biology of diesel exhaust effects on respiratory function. J Allergy Clin Immunol 2005, 115:221-228. 10.1016/j.jaci.2004.11.047, 15696072.
11. Nicod LP. Lung defenses: an overview. Eur Respir Rev 2005, 95:45-50.
12. Rothen-Rutishauser B, Schurch S, Gehr P. Interaction of particles with membranes. The toxicology of particles 2007, 139-160. CRC Press LCC, Donaldson K, Borm P.
13. Schneeberger EE, Lynch RD. Tight junctions. Their structure, composition, and function. Circ Res 1984, 55:723-733.
14. Godfrey RW. Human airway epithelial tight junctions. Microsc Res Tech 1997, 38:488-499. 10.1002/(SICI)1097-0029(19970901)38:5<488::AID-JEMT5>3.0.CO;2-E, 9376652.
15. Lehnert BE. Pulmonary and thoracic macrophage subpopulations and clearance of particles from the lung. Environ Health Perspect 1992, 97:17-46. 10.2307/3431327, 1519537, 1396454.
16. Brain JD. Lung macrophages: how many kinds are there? What do they do?. Am Rev Respir Dis 1988, 137:507-509.
17. Holt PG, Schon-Hegrad MA. Localization of T cells, macrophages and dendritic cells in rat respiratory tract tissue: implications for immune function studies. Immunology 1987, 62:349-356. 1454142, 3499375.
18. McWilliam AS, Holt PG, Gehr P. Dendritic cells as sentinels of immune surveillance in the airways. Particle-Lung Interactions: Lung Biology in Health and Disease 2000, 143:473-489. New York: Marcel Dekker Inc; New York, Gehr P, Heyder J.
19. Blank F, von Garnier C, Obregon C, Gehr P, Nicod LP. The role of dendritic cells in the lung: What do we know from in vitro models, animal models and human studies?. Exp Rev of Resp Med 2008, 2:215-233.
20. Holt PG, Schon-Hegrad MA, McMenamin PG. Dendritic cells in the respiratory tract. Int Rev Immunol 1990, 6:139-149. 10.3109/08830189009056625, 2152499.
21. Nicod LP. Function of human lung dendritic cells. 1997, 311-334. Marcle Dekker Inc, New York.
22. Holt PG. Pulmonary dendritic cells in local immunity to inert and pathogenic antigens in the respiratory tract. Proc Am Thorac Soc 2005, 2:116-120. 10.1513/pats.200502-017AW, 16113478.
23. Sung SS, Fu SM, Rose CE, Gaskin F, Ju ST, Beaty SR. A major lung CD103 (alphaE)-beta7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins. J Immunol 2006, 176:2161-2172.
24. Rescigno M, Rotta G, Valzasina B, Ricciardi-Castagnoli P. Dendritic cells shuttle microbes across gut epithelial monolayers. Immunobiology 2001, 204:572-581. 10.1078/0171-2985-00094, 11846220.
25. Rescigno M, Urbano M, Valzasina B, Francolini M, Rotta G, Bonasio R, et al. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat Immunol 2001, 2:361-367. 10.1038/86373, 11276208.
26. Rothen-Rutishauser B, Blank F, Muhlfeld C, Gehr P. In vitro models of the human eptihelial airway barrier to study the toxic potential of particulate matter. Exp Opin on drug metab and toxicol 2008, 4:1075-1089.
27. Rothen-Rutishauser BM, Kiama SG, Gehr P. A three-dimensional cellular model of the human respiratory tract to study the interaction with particles. Am J Respir Cell Mol Biol 2005, 32:281-289. 10.1165/rcmb.2004-0187OC, 15640437.
28. Blank F, Wehrli M, Baum O, Gehr P, Rothen-Rutishauser B. The epithelial integrity is preserved during particle exchange across the epithelium by macrophages and dendritic cells. European Respiratory Society 2007, E1338.
29. Niess JH, Brand S, Gu X, Landsman L, Jung S, McCormick BA, et al. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 2005, 307:254-258. 10.1126/science.1102901, 15653504.
30. Blank F, Rothen-Rutishauser B, Gehr P. Dendritic cells and macrophages form a transepithelial network against foreign particulate antigens. Am J Respir Cell Mol Biol 2007, 36:669-677. 10.1165/rcmb.2006-0234OC, 17272826.
31. Rothen-Rutishauser B, Muhlfeld C, Blank F, Musso C, Gehr P. Translocation of particles and inflammatory responses after exposure to fine particles and nanoparticles in an epithelial airway model. Part Fibre Toxicol 2007, 4:9. 10.1186/1743-8977-4-9, 2039730, 17894871.
32. Kreyling WG, Semmler-Behnke M, Moller W. Ultrafine particle-lung interactions: does size matter?. J Aerosol Med 2006, 19:74-83. 10.1089/jam.2006.19.74, 16551218.
33. Semmler-Behnke M, Kreyling WG, Lipka J, Fertsch S, Wenk A, Takenaka S, et al. Biodistribution of 1.4- and 18-nm gold particles in rats. Small 2008, 4:2108-2111. 10.1002/smll.200800922, 19031432.
34. Olivera D, Knall C, Boggs S, Seagrave J. Cytoskeletal modulation and tyrosine phosphorylation of tight junction proteins are associated with mainstream cigarette smoke-induced permeability of airway epithelium. Exp Toxicol Pathol
35. Ivanov AI. Actin motors that drive formation and disassembly of epithelial apical junctions. Front Biosci 2008, 13:6662-6681. 10.2741/3180, 18508686.
36. Müller L, Riediker M, Wick P, Mohr M, Gehr P, Rothen-Rutishauser B. Oxidative stress and inflammation response after nanoparticle exposure: differences between human lung cell mono-cultures and an advanced 3D model of the human epithelial airways. J R Soc Interface
37. Blank F, Rothen-Rutishauser BM, Schurch S, Gehr P. An optimized in vitro model of the respiratory tract wall to study particle cell interactions. J Aerosol Med 2006, 19:392-405. 10.1089/jam.2006.19.392, 17034314.
38. Rothen-Rutishauser B, Mueller L, Blank F, Brandenberger C, Muehlfeld C, Gehr P. A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles. ALTEX 2008, 25:191-196.
39. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994, 179:1109-1118. 10.1084/jem.179.4.1109, 2191432, 8145033.
40. Wan H, Winton HL, Soeller C, Stewart GA, Thompson PJ, Gruenert DC, et al. Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o-Eur Respir J 2000, 15:1058-1068. 10.1034/j.1399-3003.2000.01514.x, 10885425.
41. Forbes II. Human airway epithelial cell lines for in vitro drug transport and metabolism studies. Pharm Sci Technolo Today 2000, 3:18-27. 10.1016/S1461-5347(99)00231-X, 10637597.
42. Hartsock A, Nelson WJ. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta 2008, 1778:660-669. 10.1016/j.bbamem.2007.07.012, 2682436, 17854762.
43. Xiao GG, Wang M, Li N, Loo JA, Nel AE. Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line. J Biol Chem 2003, 278:50781-50790. 10.1074/jbc.M306423200, 14522998.
44. Doornaert B, Leblond V, Galiacy S, Gras G, Planus E, Laurent V, et al. Negative impact of DEP exposure on human airway epithelial cell adhesion, stiffness, and repair. Am J Physiol Lung Cell Mol Physiol 2003, 284:L119-L132.
45. Marano F, Boland S, Bonvallot V, Baulig A, Baeza-Squiban A. Human airway epithelial cells in culture for studying the molecular mechanisms of the inflammatory response triggered by diesel exhaust particles. Cell Biol Toxicol 2002, 18:315-320. 10.1023/A:1019548517877, 12240962.
46. Bartlett JA, Fischer AJ, McCray PB. Innate immune functions of the airway epithelium. Contrib Microbiol 2008, 15:147-163. full_text, 18511860.
47. Baulig A, Sourdeval M, Meyer M, Marano F, Baeza-Squiban A. Biological effects of atmospheric particles on human bronchial epithelial cells. Comparison with diesel exhaust particles. Toxicol In Vitro 2003, 17:567-573. 10.1016/S0887-2333(03)00115-2, 14599446.
48. Rothen-Rutishauser B, Riesen FK, Braun A, Gunthert M, Wunderli-Allenspach H. Dynamics of tight and adherens junctions under EGTA treatment. J Membr Biol 2002, 188:151-162. 10.1007/s00232-001-0182-2, 12172640.
49. Ma TY, Iwamoto GK, Hoa NT, Akotia V, Pedram A, Boivin MA, et al. TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation. Am J Physiol Gastrointest Liver Physiol 2004, 286:G367-G376. 10.1152/ajpgi.00173.2003, 14766535.
50. Kafoury RM, Madden MC. Diesel exhaust particles induce the over expression of tumor necrosis factor-alpha (TNF-alpha) gene in alveolar macrophages and failed to induce apoptosis through activation of nuclear factor-kappaB (NF-kappaB). Int J Environ Res Public Health 2005, 2:107-113. 10.3390/ijerph2005010107, 16705808.
51. Saito Y, Azuma A, Kudo S, Takizawa H, Sugawara I. Long-term inhalation of diesel exhaust affects cytokine expression in murine lung tissues: comparison between low- and high-dose diesel exhaust exposure. Exp Lung Res 2002, 28:493-506. 10.1080/01902140290096764, 12217215.
52. Rao KM, Ma JY, Meighan T, Barger MW, Pack D, Vallyathan V. Time course of gene expression of inflammatory mediators in rat lung after diesel exhaust particle exposure. Environ Health Perspect 2005, 113:612-617. 1257556, 15866772.
53. Sallusto F, Cella M, Danieli C, Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 1995, 182:389-400. 10.1084/jem.182.2.389, 2192110, 7629501.
54. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408. 10.1006/meth.2001.1262, 11846609.