Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways

Toxicology Letters

Volumn 234, Issue 1, 2015, Pages 13-19

  Abella, Vanessa ^a,b   Santoro, Anna ^c   Scotece, Morena ^a   Conde, Javier ^a   López López, Verónica ^a   Lazzaro, Veronica ^d   Gómez Reino, Juan Jesus ^a   Meli, Rosaria ^c   Gualillo, Oreste ^a  

^a Santiago University Clinical Hospital   (Spain)

^b UNIVERSITY OF A CORUÑA   (Spain)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Apoptosis; Chondrocytes; Necrosis; Non dioxin like PCBs; Oxidative stress

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PCB 101; PCB 180; POLYCHLORINATED BIPHENYL DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; LACTATE DEHYDROGENASE; MALONALDEHYDE; POLLUTANT; POLYCHLORINATED BIPHENYL;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL DEATH; CELL VIABILITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; MTT ASSAY; NONHUMAN; OXIDATIVE STRESS; POLLUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; METABOLISM; OSTEOARTHRITIS; TOXICITY;

MURINAE;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE; CELL SURVIVAL; CHONDROCYTES; ENVIRONMENTAL POLLUTANTS; HUMANS; L-LACTATE DEHYDROGENASE; MALONDIALDEHYDE; MICE; OSTEOARTHRITIS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYCHLORINATED BIPHENYLS;

EID: 84922682896     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.02.001     Document Type: Article

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