Polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) alter leptin signaling and lipid metabolism in differentiated 3T3-L1 adipocytes

Toxicology and Applied Pharmacology

Volumn 279, Issue 3, 2014, Pages 401-408

  Ferrante, Maria C ^a   Amero, Paola ^a   Santoro, Anna ^a   Monnolo, Anna ^a   Simeoli, Raffaele ^a   Di Guida, Francesca ^a   Mattace Raso, Giuseppina ^a   Meli, Rosaria ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

AMPK ACC pathway; Leptin receptor; Non dioxin like polychlorinated biphenyls; Pro inflammatory cytokines; Signal transducer and activator of transcription 3

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; DIOXIN; INTERLEUKIN 6; JANUS KINASE; LEPTIN; LEPTIN RECEPTOR; LIPID; POLYCHLORINATED BIPHENYL 101; POLYCHLORINATED BIPHENYL 153; POLYCHLORINATED BIPHENYL 180; POLYCHLORINATED BIPHENYL DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2,2',4,4',5,5' HEXACHLOROBIPHENYL; BIPHENYL; PCB 101; PCB 180; POLYCHLORINATED BIPHENYL; STAT3 PROTEIN;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; LIPID METABOLISM; METABOLIC DISORDER; MOUSE; NONHUMAN; OBESITY; POLLUTANT; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TISSUE DIFFERENTIATION; 3T3 CELL LINE; CELL DIFFERENTIATION; HUMAN; HUMAN CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; WESTERN BLOTTING;

AMPK/ACC PATHWAY; LEPTIN RECEPTOR; NON-DIOXIN-LIKE POLYCHLORINATED BIPHENYLS; PRO-INFLAMMATORY CYTOKINES; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; AZO COMPOUNDS; BLOTTING, WESTERN; CELL DIFFERENTIATION; COLORING AGENTS; ENVIRONMENTAL POLLUTANTS; INTERLEUKIN-6; LEPTIN; LIPID METABOLISM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; POLYCHLORINATED BIPHENYLS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, LEPTIN; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907192220     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.06.016     Document Type: Article

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