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1
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84899094626
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ICU-acquired weakness and recovery from critical illness
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The reviews in these 'critical care series' provide a balanced nonopinionated overview of current scientific knowledge and state-of-the-art clinical practice
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Kress JP, Hall JB. ICU-acquired weakness and recovery from critical illness. N Engl J Med 2014; 370:1626-1635. The reviews in these 'critical care series' provide a balanced nonopinionated overview of current scientific knowledge and state-of-the-art clinical practice.
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Neurological examination of critically ill patients: A pragmatic approach. Report of an ESICM expert panel
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A valuable guide in neurological assesment of the critically ill patient for clinical and scientific purposes
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Sharshar T, Citerio G, Andrews PJ, et al. Neurological examination of critically ill patients: a pragmatic approach. Report of an ESICM expert panel. Intensive Care Med 2014; 40:484-495. A valuable guide in neurological assesment of the critically ill patient for clinical and scientific purposes.
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The first article directly relating ICU-AW to compromised long-term outcome
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Hermans G, Van MH, Clerckx B, et al. Acute outcomes and 1-year mortality of ICU-acquired weakness: a cohort study and propensity matched analysis. Am J Respir Crit Care Med 2014; 190:410-420. The first article directly relating ICU-AW to compromised long-term outcome.
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Hermans, G.1
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Owais AE, Kabir SI, McNaught C, et al. A single-blinded randomised clinical trial of permissive underfeeding in patients requiring parenteral nutrition. Clin Nutr 2014; 33:997-1001.
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This RCT evaluates the impact of different feeding strategies on muscle force, microscopic myofiber wasting and ICU-AW in a large cohort of critically ill patients
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Hermans G, Casaer MP, Clerckx B, et al. Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial. Lancet Respir Med 2013; 1:621-629. This RCT evaluates the impact of different feeding strategies on muscle force, microscopic myofiber wasting and ICU-AW in a large cohort of critically ill patients.
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Needham DM, Dinglas VD, Morris PE, et al. Physical and cognitive performance of acute lung injury patients one year after initial trophic vs full enteral feeding. EDEN trial follow-up. Am J Respir Crit Care Med 2013; 188:567-576. This preplanned intention-to-treat analysis in a subgroup of EDEN patients is the first study evaluating the impact of important early nutrient restriction on long-term physical function and body composition.
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Trial of the route of early nutritional support in critically ill adults
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This large pragmatic RCT answers the question whether parenteral nutrition is harmful by itself or only in a dose-dependent manner. Isonenergetic moderately hypocaloric enteral versus parenteral nutrition provoked comparable clinical outcome
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