Reversible cell cycle inhibition and premature aging features imposed by conditional expression of p16Ink4a

Aging Cell

Volumn 14, Issue 1, 2015, Pages 139-147

  Boquoi, Amelie ^a,c   Arora, Sanjeevani ^a   Chen, Tina ^a   Litwin, Sam ^a   Koh, James ^b   Enders, Greg H ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Aging; Cdk; Ink4a; P16; Senescence; Stem cell

Indexed keywords

CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 2A;

ABDOMINAL FAT; ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; BODY WEIGHT; CATARACT; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DENTITION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GOBLET CELL; HAIR COLOR; HAIR GROWTH; HAIR LOSS; IN VITRO STUDY; IN VIVO STUDY; INTESTINAL STEM CELL; INTESTINE CELL; KYPHOSIS; MALE; MOUSE; MUTATION; NONHUMAN; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE; SUBCUTANEOUS FAT; TRANSGENE; TRANSGENIC MOUSE; WEANING; WEIGHT REDUCTION; WRINKLE; ANIMAL; CELL CYCLE; CYTOLOGY; EPITHELIUM CELL; HUMAN; INTESTINE; METABOLISM; PATHOLOGY; REPRODUCIBILITY; STEM CELL;

MAMMALIA; MUS; MUS MUSCULUS;

AGING, PREMATURE; ANIMALS; CELL CYCLE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EPITHELIAL CELLS; HUMANS; INTESTINES; MICE, TRANSGENIC; REPRODUCIBILITY OF RESULTS; STEM CELLS;

EID: 84922624477     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12279     Document Type: Article

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