Sp1 regulates Raf/MEK/ERK-induced p21CIP1 transcription in TP53-mutated cancer cells

Cellular Signalling

Volumn 27, Issue 3, 2015, Pages 479-486

  Karkhanis, Mansi ^a   Park, Jong In ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Mortalin; P21CIP1; Raf MEK ERK; Sp1; TP53

Indexed keywords

B RAF KINASE; CELL PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MORTALIN; MUTANT PROTEIN; PROTEIN P53; RAF PROTEIN; TAMOXIFEN; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE INHIBITOR 1A; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN BINDING; SMALL INTERFERING RNA; TP53 PROTEIN, HUMAN;

ARTICLE; CANCER CELL; CANCER CELL LINE; CHROMATIN IMMUNOPRECIPITATION; GENE SILENCING; HUMAN; HUMAN CELL; LNCAP CELL LINE; LUCIFERASE ASSAY; LUCIFERASE REPORTER TRUNCATION ANALYSIS; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SK MEL28 CELL LINE; TRANSCRIPTION REGULATION; U251 CELL LINE; WILD TYPE; ANTAGONISTS AND INHIBITORS; GENETICS; METABOLISM; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MAP KINASE KINASE KINASES; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS B-RAF; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84922621429     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2015.01.005     Document Type: Article

References (45)

1. Warfel N.A., El-Deiry W.S. Curr. Opin. Oncol. 2013, 25:52-58.
2. Bunz F., Dutriaux A., Lengauer C., Waldman T., Zhou S., Brown J.P., Sedivy J.M., Kinzler K.W., Vogelstein B. Science 1998, 282:1497-1501.
3. el-Deiry W.S., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mercer W.E., Kinzler K.W., Vogelstein B. Cell 1993, 75:817-825.
4. Waldman T., Kinzler K.W., Vogelstein B. Cancer Res. 1995, 55:5187-5190.
5. Abbas T., Dutta A. Nat. Rev. Cancer 2009, 9:400-414.
6. Lin S., Yang J., Elkahloun A.G., Bandyopadhyay A., Wang L., Cornell J.E., Yeh I.T., Agyin J., Tomlinson G., Sun L.Z. Mol. Biol. Cell 2012, 23:1569-1581.
7. Thaler S., Hahnel P.S., Schad A., Dammann R., Schuler M. Cancer Res. 2009, 69:1748-1757.
8. Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Cell 1997, 88:593-602.
9. Zhu J., Woods D., McMahon M., Bishop J.M. Genes Dev. 1998, 12:2997-3007.
10. Lin A.W., Barradas M., Stone J.C., van Aelst L., Serrano M., Lowe S.W. Genes Dev. 1998, 12:3008-3019.
11. Mooi W.J., Peeper D.S. N. Engl. J. Med. 2006, 355:1037-1046.
12. Daugaard M., Rohde M., Jaattela M. FEBS Lett. 2007, 581:3702-3710.
13. Wu P.K., Hong S.K., Veeranki S., Karkhanis M., Starenki D., Plaza J.A., Park J.I. Mol. Cell. Biol. 2013, 33:4051-4067.
14. Suske G. Gene 1999, 238:291-300.
15. Hong S.K., Yoon S., Moelling C., Arthan D., Park J.I. J. Biol. Chem. 2009, 284:33006-33018.
16. Beier F., Taylor A.C., LuValle P. J. Biol. Chem. 1999, 274:30273-30279.
17. Weinmann A.S., Farnham P.J. Methods 2002, 26:37-47.
18. Metivier R., Penot G., Hubner M.R., Reid G., Brand H., Kos M., Gannon F. Cell 2003, 115:751-763.
19. Parker J.B., Palchaudhuri S., Yin H., Wei J., Chakravarti D. Mol. Cell. Biol. 2012, 32:1654-1670.
20. Koutsodontis G., Tentes I., Papakosta P., Moustakas A., Kardassis D. J. Biol. Chem. 2001, 276:29116-29125.
21. Zeng Y.X., Somasundaram K., el-Deiry W.S. Nat. Genet. 1997, 15:78-82.
22. Gartel A.L., Najmabadi F., Goufman E., Tyner A.L. Oncogene 2000, 19:961-964.
23. Sowa Y., Orita T., Hiranabe-Minamikawa S., Nakano K., Mizuno T., Nomura H., Sakai T. Ann. N. Y. Acad. Sci. 1999, 886:195-199.
24. De Siervi A., Marinissen M., Diggs J., Wang X.F., Pages G., Senderowicz A. Cancer Res. 2004, 64:743-750.
25. Wang L.G., Liu X.M., Fang Y., Dai W., Chiao F.B., Puccio G.M., Feng J., Liu D., Chiao J.W. Int. J. Oncol. 2008, 33:375-380.
26. Chew Y.C., Adhikary G., Wilson G.M., Xu W., Eckert R.L. J. Biol. Chem. 2012, 287:16168-16178.
27. Samuels M.L., Weber M.J., Bishop J.M., McMahon M. Mol. Cell. Biol. 1993, 13:6241-6252.
28. Ji Z., Njauw C.N., Taylor M., Neel V., Flaherty K.T., Tsao H. J. Investig. Dermatol. 2012, 132:356-364.
29. Shin S.Y., Kim C.G., Lim Y., Lee Y.H. J. Biol. Chem. 2011, 286:26860-26872.
30. Park J.S., Qiao L., Gilfor D., Yang M.Y., Hylemon P.B., Benz C., Darlington G., Firestone G., Fisher P.B., Dent P. Mol. Biol. Cell 2000, 11:2915-2932.
31. Bellido T., O'Brien C.A., Roberson P.K., Manolagas S.C. J. Biol. Chem. 1998, 273:21137-21144.
32. de Keizer P.L., Packer L.M., Szypowska A.A., Riedl-Polderman P.E., van den Broek N.J., de Bruin A., Dansen T.B., Marais R., Brenkman A.B., Burgering B.M. Cancer Res. 2010, 70:8526-8536.
33. Nakano K., Mizuno T., Sowa Y., Orita T., Yoshino T., Okuyama Y., Fujita T., Ohtani-Fujita N., Matsukawa Y., Tokino T., Yamagishi H., Oka T., Nomura H., Sakai T. J. Biol. Chem. 1997, 272:22199-22206.
34. Zhang W., Geiman D.E., Shields J.M., Dang D.T., Mahatan C.S., Kaestner K.H., Biggs J.R., Kraft A.S., Yang V.W. J. Biol. Chem. 2000, 275:18391-18398.
35. Koutsodontis G., Moustakas A., Kardassis D. Biochemistry 2002, 41:12771-12784.
36. Tan N.Y., Khachigian L.M. Mol. Cell. Biol. 2009, 29:2483-2488.
37. Chu S., Ferro T.J. Gene 2005, 348:1-11.
38. Waby J.S., Chirakkal H., Yu C., Griffiths G.J., Benson R.S., Bingle C.D., Corfe B.M. Mol. Cancer 2010, 9:275.
39. Majumdar G., Harrington A., Hungerford J., Martinez-Hernandez A., Gerling I.C., Raghow R., Solomon S. J. Biol. Chem. 2006, 281:3642-3650.
40. Spengler M.L., Brattain M.G. J. Biol. Chem. 2006, 281:5567-5574.
41. Milanini-Mongiat J., Pouyssegur J., Pages G. J. Biol. Chem. 2002, 277:20631-20639.
42. Yan G.Z., Ziff E.B. J. Neurosci. 1997, 17:6122-6132.
43. Ventura A., Kirsch D.G., McLaughlin M.E., Tuveson D.A., Grimm J., Lintault L., Newman J., Reczek E.E., Weissleder R., Jacks T. Nature 2007, 445:661-665.
44. Xue W., Zender L., Miething C., Dickins R.A., Hernando E., Krizhanovsky V., Cordon-Cardo C., Lowe S.W. Nature 2007, 445:656-660.
45. Sullivan K.D., Gallant-Behm C.L., Henry R.E., Fraikin J.L., Espinosa J.M. Biochim. Biophys. Acta 2012, 1825:229-244.