Comparison of a continuous ring layer wet granulation process with batch high shear and fluidized bed granulation processes

Powder Technology

Volumn 275, Issue , 2015, Pages 113-120

  Järvinen, Maiju A ^a   Paavola, Marko ^b   Poutiainen, Sami ^a   Itkonen, Päivi ^a   Pasanen, Ville ^a   Uljas, Katja ^a   Leiviskä, Kauko ^b   Juuti, Mikko ^c   Ketolainen, Jarkko ^a   Järvinen, Kristiina ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF OULU   (Finland)

^c VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

Continuous ring layer process; Fluidized bed process; High shear process; PLS model; Wet granulation

Indexed keywords

BINDERS; DRUG PRODUCTS; FLOW RATE; FLUIDIZATION; FLUIDIZED BED PROCESS; FLUIDIZED BEDS; GRANULATION; INLET FLOW; SHEAR FLOW;

FLUIDIZED BED GRANULATION; HIGH SHEAR; MICRO-CRYSTALLINE CELLULOSE; PHARMACEUTICAL GRANULES; PLS MODELING; POLY VINYL PYRROLIDONE; WET GRANULATION; WET GRANULATION TECHNIQUE;

PROCESS CONTROL;

MICROCRYSTALLINE CELLULOSE; PARACETAMOL; POVIDONE;

ARTICLE; BATCH PROCESS; CONTINUOUS RING LAYER GRANULATION PROCESS; CONTROLLED STUDY; DRUG GRANULATION; DRUG GRANULE; DRUG RELEASE; DRUG SOLUBILITY; FLOW RATE; FLUIDIZED BED; FLUIDIZED BED GRANULATION PROCESS; HIGH SHEAR GRANULATION PROCESS; INTERMETHOD COMPARISON; QUANTITATIVE ANALYSIS; TABLET COMPRESSION; TABLET FORMULATION;

EID: 84922612861     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2015.01.071     Document Type: Article

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