Characterization of continuous convective powder mixing processes

Powder Technology

Volumn 182, Issue 3, 2008, Pages 368-378

  Portillo, Patricia M ^a   Ierapetritou, Marianthi G ^a   Muzzio, Fernando J ^a  

^a The State University of New Jersey   (United States)

Author keywords

Continuous mixing; Powders; Relative Standard Deviation; Residence time; Variance Reduction Ratio

Indexed keywords

DRUG PRODUCTS; INFRARED SPECTROSCOPY; POWDERS;

BLADE ANGLE; CONTINUOUS MIXING; PROCESS ANALYTICAL TECHNOLOGY (PAT);

MIXERS (MACHINERY);

LACTOSE; PARACETAMOL;

DRUG PRODUCTS; INFRARED SPECTROSCOPY; MIXERS (MACHINERY); POWDERS;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL PROCEDURES; DRUG FORMULATION; MIXER; NEAR INFRARED SPECTROSCOPY; POWDER; PROCESS TECHNOLOGY; REACTION TIME; ROTATION; SCALE UP; SHEAR FLOW; TECHNOLOGY; THERMODYNAMICS;

EID: 39649115001     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2007.06.024     Document Type: Article

References (29)

1. Laurent B.F.C., and Bridgwater J. Convection and segregation in a horizontal mixer. Powder Technology 123 (2002) 9-18
2. Laurent B.F.C., and Bridgwater J. Performance of single and size-bladed powder mixers. Chemical Engineering Science 57 (2002) 1695-1709
3. Laurent B.F.C., and Bridgwater J. Influence of agitator design on powder flow. Chemical Engineering Science 57 (2002) 3781-3793
4. Muerza S., Berthiaux H., Massol-Chaudeur S., and Thomas G. A dynamic study of static mixing using on-line image analysis. Powder Technology 128 (2002) 195-204
5. Sudah O., Chester A.W., Kowalski J.A., Beeckman J.W., and Muzzio F.J. Quantitative characterization of mixing processes in rotary calciners. Powder Technology 126 (2002) 166-173
6. Weinkötter R., and Reh L. Characterization of particulate mixtures by in-line measurements. Particle and Particle Systems Characterization 11 4 (1994) 284-290
7. Kehlenbeck V., and Sommer K. Possibilities to improve the short-term dosing constancy of volumetric feeders. Powder Technology 138 (2003) 51-56
8. Williams J.C. Segregation of particulate materials-a review. Powder Technology 15 2 (1976) 245-251
9. Pernenkil L., and Cooney C. A review on the continuous blending of powders. Chemical Engineering Science 61 (2006) 720-742
10. Williams J., and Rahman M. Prediction of the performance of continuous mixers for particulate solids using residence time distributions Part I: theoretical. Powder Technology 5 (1971) 87-92
11. Beaudry J.P. Blender efficiency. Chemical Engineer 55 (1948) 112-113
12. Williams J., and Rahman M. Prediction of the performance of continuous mixers for particulate solids using residence time distributions, Part II: experimental. Powder Technology 5 (1971) 307-316
13. Harwood C., Walanski K., Luebcke E., and Swanstrom C. The performance of continuous mixers for dry powders. Powder Technology 11 (1975) 289-296
14. Weinekötter R., and Reh L. Continuous mixing of fine particles. Particle and Particle Systems Characterization 12 1 (1995) 46-53
15. Berthiaux H., Marikh K., Mizonov V., Ponomarev D., and Barantzeva E. Modeling continuous powder mixing by means of the theory of Markov chains. Particulate Science and Technology 22 4 (2004) 379-389
16. Dankwerts P.V. Continuous flow systems: distribution of residence times. Chemical Engineering Science (1953) 21-11
17. EL-Hagrasy A.S., Morris H.R., D'Amico F., Lodder R.A., and Drennen III J.K. Near-infrared spectroscopy and imaging for the monitoring of powder blend homogeneity. Journal of Pharmaceutical Sciences 90 9 (2001) 1298-1307
18. Weinekötter R., and Reh L. Mixing of Solids (2000), Kluwer Academic Publishers, Dordrecht
19. Gupta S.D., Khakhar D.V., and Bhatia S.K. Axial segregation of particles in a horizontal rotating cylinder. Chemical Engineering Science 46 (1991) 1513-1517
20. Kenney J.F., and Keeping E.S. Geometric mean. Mathematics of Statistics, 3rd ed. (1962), Van Nostrand, Princeton, NJ 54-55
21. Bailey A.G. Electrostatic phenomena during powder handling. Powder Technology 37 (1984) 71-85
22. Dammer S.M., Werth J., and Hinrichsen H. Electrostatically charged granular matter. In: Hinrichsen H., and Wolf D.E. (Eds). The Physics of Granular Media (2004) 253-280
23. Porion P., Sommier N., Faugeréa A.M., and Evesque P. Dynamics of size segregation and mixing of granular materials in a 3D-blender by NMR imaging investigation. Powder Technology 141 (2004) 55-68
24. Alexander A., Shinbrot T., and Muzzio F.J. Granular segregation in the double-cone blender: transitions and mechanisms. Physics of Fluids 13 3 (2001) 578-587
25. Liss E.D., Conway S.L., Zega J.A., and Glasser B.J. Segregation of powders during gravity flow through vertical pipes. Pharmaceutical Technology (2004)
26. Orband J.L.R., and Geldart D. Direct measurement of powder cohesion using a torsional device. Powder Technology 92 (1997) 25-33
27. Liss E.D., and Glasser B.J. The influence of clusters on the stress in a sheared granular material. Powder Technology 116 (2001) 116-132
28. Marikh K., Berthiaux H., Mizonov V., and Barantseva E. Experimental study of the stirring conditions taking place in a pilot plant continuous mixer of particulate solids. Powder Technology 157 (2005) 138-143
29. Conway S.L., Lekhal A., Khinast J.G., and Glasser B.J. Granular flow and segregation in a four-bladed mixer. Chemical Engineering Science 60 (2005) 7091-7107