Transmembrane inhibitor of RICTOR/mTORC2 in hematopoietic progenitors

Stem Cell Reports

Volumn 3, Issue 5, 2014, Pages 832-840

  Lee, Dongjun ^a,b,c   Sykes, Stephen M ^a,b,c   Kalaitzidis, Demetrios ^a,b,c   Lane, Andrew A ^a,b,c,d   Kfoury, Youmna ^a,b,c   Raaijmakers, Marc H G P ^e   Wang, Ying Hua ^a,b,c   Armstrong, Scott A ^f   Scadden, David T ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b Harvard University   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MEMBRANE PROTEIN; PROTEIN KINASE B; PROTEIN KINASE C ALPHA; PROTEIN NDRG1; PROTEIN RICTOR; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; CARRIER PROTEIN; CELL CYCLE PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; N-MYC DOWNSTREAM-REGULATED GENE 1 PROTEIN; NOTCH RECEPTOR; PROTEIN BINDING; RICTOR PROTEIN, MOUSE; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ARTICLE; CANCER MORTALITY; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; 3T3 CELL LINE; ANIMAL; CELL CULTURE; CYTOLOGY; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOBLOTTING; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSGENIC MOUSE;

ANIMALIA;

ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELLS, CULTURED; FORKHEAD TRANSCRIPTION FACTORS; HEK293 CELLS; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOBLOTTING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MULTIPROTEIN COMPLEXES; NIH 3T3 CELLS; PHOSPHORYLATION; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN BINDING; PROTEIN KINASE C-ALPHA; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TOR SERINE-THREONINE KINASES;

EID: 84922574232     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2014.08.011     Document Type: Article

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