Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: Anti-CTGF monoclonal antibody attenuates leukemia growth

Annals of Hematology

Volumn 93, Issue 3, 2014, Pages 485-492

  Lu, Hongbo ^a   Kojima, Kensuke ^a   Battula, Venkata Lokesh ^a   Korchin, Borys ^a   Shi, Yuexi ^a   Chen, Ye ^a   Spong, Suzanne ^b   Thomas, Deborah A ^a   Kantarjian, Hagop ^a   Lock, Richard B ^c   Andreeff, Michael ^a   Konopleva, Marina ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b FIBROGEN INC   (United States)

^c CHILDREN S CANCER INSTITUTE AUSTRALIA FOR MEDICAL RESEARCH   (Australia)

Author keywords

ALL; Apoptosis; CTGF

Indexed keywords

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; ASPARAGINASE; CELL LINE, TUMOR; CHILD; CONNECTIVE TISSUE GROWTH FACTOR; DEXAMETHASONE; GENE SILENCING; HUMANS; MICE; MICE, SCID; MOLECULAR TARGETED THERAPY; NEOPLASM PROTEINS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SIGNAL TRANSDUCTION; TUMOR BURDEN; TUMOR CELLS, CULTURED; VINCRISTINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84894321449     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-013-1939-2     Document Type: Article

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