Antiproliferative activity of n-butanol floral extract from butea monosperma against hct 116 colon cancer cells; drug likeness properties and in silico evaluation of their active compounds toward glycogen synthase kinase-3β/axin and β-catenin/t-cell factor-4 protein complex

Asian Journal of Pharmaceutical and Clinical Research

Volumn 8, Issue 1, 2015, Pages 134-141

  Polachi, Navaneethakrishnan ^a   Nagaraja, Prashantha ^b   Subramaniyan, Boopathi ^a   Mathan, Ganeshan ^a  

^a BHARATHIDASAN UNIVERSITY   (India)

^b Bioinformatics Group   (India)

Author keywords

Absorption; Butea monosperma; Colorectal cancer; Distribution; Excretion and toxicity; Glycogen synthase kinase 3 Axin; Metabolism; Molecular docking; catenin T Cell factor 4

Indexed keywords

ANTINEOPLASTIC AGENT; AXIN; BETA CATENIN; BUTANOL; BUTEA MONOSPERMA EXTRACT; BUTEIN; BUTRIN; GLYCOGEN SYNTHASE KINASE 3BETA; ISOBUTRIN; ISOCOREOPSIN; ISOMONOSPERMOSIDE; MONOSPERMOSIDE; NIKETHAMIDE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; QUERCETIN; T CELL FACTOR 4 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BUTEA MONOSPERMA; CANCER CELL LINE; CANCER INHIBITION; COLON CANCER; COMPUTER MODEL; COMPUTER PROGRAM; DRUG ABSORPTION; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; FLOWER; HUMAN; HUMAN CELL; HYDROGEN BOND; IC50; LD50; MOLECULAR DOCKING; MOUSE; NONHUMAN; PHARMACOPHORE; PHYTOCHEMISTRY; PROTEIN EXPRESSION; PROTEIN STRUCTURE;

EID: 84922568685     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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