Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycle

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1854, Issue 5, 2015, Pages 341-348

  Cortines, Juliana R ^a   Lima, Luís Mauricio T R ^a   Mohana Borges, Ronaldo ^a   De Millen, Thiago A ^a   Gaspar, Luciane Pinto ^a,c   Lanman, Jason K ^b,d   Prevelige, Peter E ^b   Silva, Jerson L ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b University of Alabama at Birmingham   (United States)

^c Instituto de Technologia em Imunobiologicos   (Brazil)

^d PURDUE UNIVERSITY   (United States)

Author keywords

Capsid protein; Cyclophilin; High hydrostatic pressure; Human immunodeficiency virus; SAXS

Indexed keywords

CAPSID PROTEIN; CYCLOPHILIN A; DIMER; CAPSID PROTEINS; PROTEIN BINDING;

ARTICLE; ATMOSPHERIC PRESSURE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; DENATURATION; FLUORESCENCE SPECTROSCOPY; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROSTATIC PRESSURE; IN VITRO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STABILITY; SMALL ANGLE SCATTERING; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMISTRY; HIV-1; HUMANS; METABOLISM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYSIOLOGY; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; SCATTERING, SMALL ANGLE; VIRUS ASSEMBLY; X-RAY DIFFRACTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MIRIDAE;

AMINO ACID SEQUENCE; CAPSID PROTEINS; CYCLOPHILIN A; HIV-1; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; SCATTERING, SMALL ANGLE; VIRUS ASSEMBLY; X-RAY DIFFRACTION;

EID: 84922553321     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2014.12.008     Document Type: Article

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