TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages

Journal of Immunology

Volumn 194, Issue 4, 2015, Pages 1928-1937

  Zheng, Shasha ^a   Hedl, Matija ^a   Abraham, Clara ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AXL RECEPTOR; CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERLEUKIN 10; MER RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; PROTEIN C JUN; RECEPTOR PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR MAFK; TRANSCRIPTION FACTOR PU 1; TRANSFORMING GROWTH FACTOR BETA; TYRO3 RECEPTOR; UNCLASSIFIED DRUG; CYTOKINE; NOD2 PROTEIN, HUMAN; PROTEIN TYROSINE KINASE; SOCS3 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; INTERLEUKIN 10 GENE; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHROMATIN IMMUNOPRECIPITATION; COLITIS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; COLITIS; CYTOKINES; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; NOD2 SIGNALING ADAPTOR PROTEIN; RECEPTOR PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSFECTION;

EID: 84922504294     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401933     Document Type: Article

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