-
1
-
-
84888645566
-
WHO's 2013 global report on tuberculosis: Successes threats and opportunities
-
Zumla, A. George, A., Sharma, V., Herbert, N. & Baroness Masham of Ilton. WHO's 2013 global report on tuberculosis: successes, threats, and opportunities. Lancet 382, 1765-1767 (2013).
-
(2013)
Lancet
, vol.382
, pp. 1765-1767
-
-
Zumla, A.1
George, A.2
Sharma, V.3
Herbert, N.4
-
2
-
-
67650164516
-
Mycobacterial survival strategies in the phagosome: Defence against host stresses
-
Ehrt, S. & Schnappinger, D. Mycobacterial survival strategies in the phagosome: defence against host stresses. Cell. Microbiol. 11, 1170-1178 (2009).
-
(2009)
Cell. Microbiol.
, vol.11
, pp. 1170-1178
-
-
Ehrt, S.1
Schnappinger, D.2
-
3
-
-
0035584286
-
Mycobacterial persistence: Adaptation to a changing environment
-
Honer zu Bentrup, K. & Russell, D. G. Mycobacterial persistence: adaptation to a changing environment. Trends Microbiol. 9, 597-605 (2001).
-
(2001)
Trends Microbiol.
, vol.9
, pp. 597-605
-
-
Honer Zu Bentrup, K.1
Russell, D.G.2
-
4
-
-
67650132403
-
Hypoxia: A window into Mycobacterium tuberculosis latency
-
Rustad, T. R., Sherrid, A. M., Minch, K. J. & Sherman, D. R. Hypoxia: a window into Mycobacterium tuberculosis latency. Cell. Microbiol. 11, 1151-1159 (2009).
-
(2009)
Cell. Microbiol.
, vol.11
, pp. 1151-1159
-
-
Rustad, T.R.1
Sherrid, A.M.2
Minch, K.J.3
Sherman, D.R.4
-
5
-
-
0035432383
-
Mycobacterium tuberculosis: Here today, and here tomorrow
-
Russell, D. G. Mycobacterium tuberculosis: here today, and here tomorrow. Nature Rev. Mol. Cell Biol. 2, 569-577 (2001).
-
(2001)
Nature Rev. Mol. Cell Biol.
, vol.2
, pp. 569-577
-
-
Russell, D.G.1
-
6
-
-
84879214891
-
Feast or famine: The host-pathogen battle over amino acids
-
Zhang, Y. J. & Rubin, E. J. Feast or famine: the host-pathogen battle over amino acids. Cell. Microbiol. 15, 1079-1087 (2013).
-
(2013)
Cell. Microbiol.
, vol.15
, pp. 1079-1087
-
-
Zhang, Y.J.1
Rubin, E.J.2
-
7
-
-
77952884163
-
Carbon metabolism of intracellular bacterial pathogens and possible links to virulence
-
Eisenreich, W., Dandekar, T., Heesemann, J. & Goebel, W. Carbon metabolism of intracellular bacterial pathogens and possible links to virulence. Nature Rev. Microbiol. 8, 401-412 (2010).
-
(2010)
Nature Rev. Microbiol.
, vol.8
, pp. 401-412
-
-
Eisenreich, W.1
Dandekar, T.2
Heesemann, J.3
Goebel, W.4
-
8
-
-
35448984675
-
Nitrogen regulation in bacteria and archaea
-
Leigh, J. A. & Dodsworth, J. A. Nitrogen regulation in bacteria and archaea. Annu. Rev. Microbiol. 61, 349-377 (2007).
-
(2007)
Annu. Rev. Microbiol.
, vol.61
, pp. 349-377
-
-
Leigh, J.A.1
Dodsworth, J.A.2
-
9
-
-
67649410544
-
A genomic view on nitrogen metabolism and nitrogen control in mycobacteria
-
Amon, J., Titgemeyer, F. & Burkovski, A. A genomic view on nitrogen metabolism and nitrogen control in mycobacteria. J. Mol. Microbiol. Biotechnol. 17, 20-29 (2009).
-
(2009)
J. Mol. Microbiol. Biotechnol.
, vol.17
, pp. 20-29
-
-
Amon, J.1
Titgemeyer, F.2
Burkovski, A.3
-
10
-
-
84893156134
-
The role of glutamine oxoglutarate aminotransferase and glutamate dehydrogenase in nitrogen metabolism in Mycobacterium bovis BCG
-
Viljoen, A. J., Kirsten, C. J., Baker, B., van Helden, P. D. & Wiid, I. J. The role of glutamine oxoglutarate aminotransferase and glutamate dehydrogenase in nitrogen metabolism in Mycobacterium bovis BCG. PLoS ONE 8, e84452 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e84452
-
-
Viljoen, A.J.1
Kirsten, C.J.2
Baker, B.3
Van Helden, P.D.4
Wiid, I.J.5
-
11
-
-
0032508046
-
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
-
Cole, S. T. et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393, 537-544 (1998).
-
(1998)
Nature
, vol.393
, pp. 537-544
-
-
Cole, S.T.1
-
12
-
-
0038309776
-
Glutamine synthetase GlnA1 is essential for growth of Mycobacterium tuberculosis in human THP-1 macrophages and guinea pigs
-
Tullius, M. V., Harth, G. & Horwitz, M. A. Glutamine synthetase GlnA1 is essential for growth of Mycobacterium tuberculosis in human THP-1 macrophages and guinea pigs. Infect. Immun. 71, 3927-3936 (2003).
-
(2003)
Infect. Immun.
, vol.71
, pp. 3927-3936
-
-
Tullius, M.V.1
Harth, G.2
Horwitz, M.A.3
-
13
-
-
77953194775
-
Common patterns-unique features: Nitrogen metabolism and regulation in Gram-positive bacteria
-
Amon, J., Titgemeyer, F. & Burkovski, A. Common patterns-unique features: nitrogen metabolism and regulation in Gram-positive bacteria. FEMS Microbiol. Rev. 34, 588-605 (2010).
-
(2010)
FEMS Microbiol. Rev.
, vol.34
, pp. 588-605
-
-
Amon, J.1
Titgemeyer, F.2
Burkovski, A.3
-
14
-
-
0035105144
-
P(II) signal transduction proteins, pivotal players in microbial nitrogen control
-
Arcondeguy, T., Jack, R. & Merrick, M. P(II) signal transduction proteins, pivotal players in microbial nitrogen control. Microbiol. Mol. Biol. Rev. 65, 80-105 (2001).
-
(2001)
Microbiol. Mol. Biol. Rev.
, vol.65
, pp. 80-105
-
-
Arcondeguy, T.1
Jack, R.2
Merrick, M.3
-
15
-
-
0033819147
-
GlnE is an essential gene in Mycobacterium tuberculosis
-
Parish, T. & Stoker, N. G. glnE is an essential gene in Mycobacterium tuberculosis. J. Bacteriol. 182, 5715-5720 (2000).
-
(2000)
J. Bacteriol.
, vol.182
, pp. 5715-5720
-
-
Parish, T.1
Stoker, N.G.2
-
16
-
-
77955114169
-
Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein
-
Shetty, N. D., Reddy, M. C., Palaninathan, S. K., Owen, J. L. & Sacchettini, J. C. Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein. Protein Sci. 19, 1513-1524 (2010).
-
(2010)
Protein Sci.
, vol.19
, pp. 1513-1524
-
-
Shetty, N.D.1
Reddy, M.C.2
Palaninathan, S.K.3
Owen, J.L.4
Sacchettini, J.C.5
-
17
-
-
84875226526
-
Adenylylation of mycobacterial Glnk (PII) protein is induced by nitrogen limitation
-
Williams, K. J., Bennett, M. H., Barton, G. R., Jenkins, V. A. & Robertson, B. D. Adenylylation of mycobacterial Glnk (PII) protein is induced by nitrogen limitation. Tuberculosis (Edinb.) 93, 198-206 (2013).
-
(2013)
Tuberculosis (Edinb.)
, vol.93
, pp. 198-206
-
-
Williams, K.J.1
Bennett, M.H.2
Barton, G.R.3
Jenkins, V.A.4
Robertson, B.D.5
-
18
-
-
34250760897
-
The role of GlnD in ammonia assimilation in Mycobacterium tuberculosis
-
Read, R., Pashley, C. A., Smith, D. & Parish, T. The role of GlnD in ammonia assimilation in Mycobacterium tuberculosis. Tuberculosis (Edinb.) 87, 384-390 (2007).
-
(2007)
Tuberculosis (Edinb.)
, vol.87
, pp. 384-390
-
-
Read, R.1
Pashley, C.A.2
Smith, D.3
Parish, T.4
-
19
-
-
2542474955
-
Adenylylation and catalytic properties of Mycobacterium tuberculosis glutamine synthetase expressed in Escherichia coli versus mycobacteria
-
Mehta, R. et al. Adenylylation and catalytic properties of Mycobacterium tuberculosis glutamine synthetase expressed in Escherichia coli versus mycobacteria. J. Biol. Chem. 279, 22477-22482 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22477-22482
-
-
Mehta, R.1
-
20
-
-
66149097000
-
An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis
-
Nott, T. J. et al. An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis. Sci Signal 2, ra12 (2009).
-
(2009)
Sci Signal 2, ra12
-
-
Nott, T.J.1
-
21
-
-
56749105898
-
Regulation of glutamate metabolism by protein kinases in mycobacteria
-
O'Hare, H. M. et al. Regulation of glutamate metabolism by protein kinases in mycobacteria. Mol. Microbiol. 70, 1408-1423 (2008).
-
(2008)
Mol. Microbiol.
, vol.70
, pp. 1408-1423
-
-
O'Hare, H.M.1
-
22
-
-
20744445530
-
Proteomic identification of M. Tuberculosi s protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions
-
Villarino, A. et al. Proteomic identification of M. tuberculosi s protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions. J. Mol. Biol. 350, 953-963 (2005).
-
(2005)
J. Mol. Biol.
, vol.350
, pp. 953-963
-
-
Villarino, A.1
-
23
-
-
65649121899
-
The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis
-
Malm, S. et al. The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis. Microbiology 155, 1332-1339 (2009).
-
(2009)
Microbiology
, vol.155
, pp. 1332-1339
-
-
Malm, S.1
-
24
-
-
84876987238
-
Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis
-
Jenkins, V. A., Barton, G. R., Robertson, B. D. & Williams, K. J. Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis. BMC Genomics 14, 301 (2013).
-
(2013)
BMC Genomics
, vol.14
, pp. 301
-
-
Jenkins, V.A.1
Barton, G.R.2
Robertson, B.D.3
Williams, K.J.4
-
25
-
-
84887873037
-
Nitrogen starvation-induced transcriptome alterations and influence of transcription regulator mutants in Mycobacterium smegmatis
-
Jessberger, N. et al. Nitrogen starvation-induced transcriptome alterations and influence of transcription regulator mutants in Mycobacterium smegmatis. BMC Res. Notes 6, 482 (2013).
-
(2013)
BMC Res. Notes
, vol.6
, pp. 482
-
-
Jessberger, N.1
-
26
-
-
84903271497
-
Amino acid capture and utilization within the Mycobacterium tuberculosis phagosome
-
Gouzy, A., Poquet, Y. & Neyrolles, O. Amino acid capture and utilization within the Mycobacterium tuberculosis phagosome. Future Microbiol. 9, 631-637 (2014).
-
(2014)
Future Microbiol.
, vol.9
, pp. 631-637
-
-
Gouzy, A.1
Poquet, Y.2
Neyrolles, O.3
-
27
-
-
0001062786
-
Utilization of amino acids during growth of Mycobacterium tuberculosis in rotary cultures
-
Lyon, R. H., Hall, W. H. & Costas-Martinez, C. Utilization of amino acids during growth of Mycobacterium tuberculosis in rotary cultures. Infect. Immun. 1, 513-520 (1970).
-
(1970)
Infect. Immun.
, vol.1
, pp. 513-520
-
-
Lyon, R.H.1
Hall, W.H.2
Costas-Martinez, C.3
-
28
-
-
42949135614
-
Nutrient acquisition by mycobacteria
-
Niederweis, M. Nutrient acquisition by mycobacteria. Microbiology 154, 679-692 (2008).
-
(2008)
Microbiology
, vol.154
, pp. 679-692
-
-
Niederweis, M.1
-
29
-
-
84856695691
-
Nitrate reduction pathways in mycobacteria and their implications during latency
-
Khan, A. & Sarkar, D. Nitrate reduction pathways in mycobacteria and their implications during latency. Microbiology 158, 301-307 (2012).
-
(2012)
Microbiology
, vol.158
, pp. 301-307
-
-
Khan, A.1
Sarkar, D.2
-
30
-
-
84866481440
-
Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacterium tuberculosis
-
Giffin, M. M., Raab, R. W., Morganstern, M. & Sohaskey, C. D. Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacterium tuberculosis. PLoS ONE 7, e45459 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e45459
-
-
Giffin, M.M.1
Raab, R.W.2
Morganstern, M.3
Sohaskey, C.D.4
-
31
-
-
84895458423
-
Systems-based approaches to probing metabolic variation within the Mycobacterium tuberculosis complex
-
Lofthouse, E. K. et al. Systems-based approaches to probing metabolic variation within the Mycobacterium tuberculosis complex. PLoS ONE 8, e75913 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e75913
-
-
Lofthouse, E.K.1
-
32
-
-
84895761851
-
Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection
-
Gouzy, A. et al. Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection. PLoS Pathog. 10, e1003928 (2014).
-
(2014)
PLoS Pathog.
, vol.10
, pp. e1003928
-
-
Gouzy, A.1
-
33
-
-
50049085780
-
Anaerobic arginine metabolism of Mycobacterium tuberculosis is mediated by arginine deiminase (arcA), but is not essential for chronic persistence in an aerogenic mouse model of infection
-
Surken, M., Keller, C., Rohker, C., Ehlers, S. & Bange, F. C. Anaerobic arginine metabolism of Mycobacterium tuberculosis is mediated by arginine deiminase (arcA), but is not essential for chronic persistence in an aerogenic mouse model of infection. Int. J. Med. Microbiol. 298, 657-661 (2008).
-
(2008)
Int. J. Med. Microbiol.
, vol.298
, pp. 657-661
-
-
Surken, M.1
Keller, C.2
Rohker, C.3
Ehlers, S.4
Bange, F.C.5
-
34
-
-
84857848741
-
Uptake of sulphate but not phosphate by Mycobacterium tuberculosis is slower than that for Mycobacterium smegmatis
-
Song, H. & Niederweis, M. Uptake of sulphate but not phosphate by Mycobacterium tuberculosis is slower than that for Mycobacterium smegmatis. J. Bacteriol. 194, 956-964 (2012).
-
(2012)
J. Bacteriol.
, vol.194
, pp. 956-964
-
-
Song, H.1
Niederweis, M.2
-
35
-
-
84886600677
-
Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate
-
Gouzy, A. et al. Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate. Nature Chem. Biol. 9, 674-676 (2013).
-
(2013)
Nature Chem. Biol.
, vol.9
, pp. 674-676
-
-
Gouzy, A.1
-
36
-
-
0033973240
-
Amino acid transport and metabolism in mycobacteria: Cloning, interruption, and characterization of an l-Arginine/γ-aminobutyric acid permease in Mycobacterium bovis BCG
-
Seth, A. & Connell, N. D. Amino acid transport and metabolism in mycobacteria: cloning, interruption, and characterization of an l-Arginine/γ-aminobutyric acid permease in Mycobacterium bovis BCG. J. Bacteriol. 182, 919-927 (2000).
-
(2000)
J. Bacteriol.
, vol.182
, pp. 919-927
-
-
Seth, A.1
Connell, N.D.2
-
37
-
-
44349094977
-
Glycine betaine uptake by the ProXVWZ ABC transporter contributes to the ability of Mycobacterium tuberculosis to initiate growth in human macrophages
-
Price, C. T., Bukka, A., Cynamon, M. & Graham, J. E. Glycine betaine uptake by the ProXVWZ ABC transporter contributes to the ability of Mycobacterium tuberculosis to initiate growth in human macrophages. J. Bacteriol. 190, 3955-3961 (2008).
-
(2008)
J. Bacteriol.
, vol.190
, pp. 3955-3961
-
-
Price, C.T.1
Bukka, A.2
Cynamon, M.3
Graham, J.E.4
-
38
-
-
72749117648
-
Mycobacterium tuberculosis modulates its cell surface via an oligopeptide permease (Opp) transport system
-
Flores-Valdez, M. A., Morris, R. P., Laval, F., Daffe, M. & Schoolnik, G. K. Mycobacterium tuberculosis modulates its cell surface via an oligopeptide permease (Opp) transport system. FASEB J. 23, 4091-4104 (2009).
-
(2009)
FASEB J.
, vol.23
, pp. 4091-4104
-
-
Flores-Valdez, M.A.1
Morris, R.P.2
Laval, F.3
Daffe, M.4
Schoolnik, G.K.5
-
39
-
-
0033972395
-
A peptide permease mutant of Mycobacterium bovis BCG resistant to the toxic peptides glutathione and S-nitrosoglutathione
-
Green, R. M., Seth, A. & Connell, N. D. A peptide permease mutant of Mycobacterium bovis BCG resistant to the toxic peptides glutathione and S-nitrosoglutathione. Infect. Immun. 68, 429-436 (2000).
-
(2000)
Infect. Immun.
, vol.68
, pp. 429-436
-
-
Green, R.M.1
Seth, A.2
Connell, N.D.3
-
40
-
-
0033819143
-
The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis
-
Braibant, M., Gilot, P. & Content, J. The ATP binding cassette (ABC) transport systems of Mycobacterium tuberculosis. FEMS Microbiol. Rev. 24, 449-467 (2000).
-
(2000)
FEMS Microbiol. Rev.
, vol.24
, pp. 449-467
-
-
Braibant, M.1
Gilot, P.2
Content, J.3
-
41
-
-
84864818523
-
Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism
-
Lin, W. et al. Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism. Infect. Immun. 80, 2771-2779 (2012).
-
(2012)
Infect. Immun.
, vol.80
, pp. 2771-2779
-
-
Lin, W.1
-
42
-
-
0029591917
-
Purification, characterization, and genetic analysis of Mycobacterium tuberculosis urease, a potentially critical determinant of host-pathogen interaction
-
Clemens, D. L., Lee, B. Y. & Horwitz, M. A. Purification, characterization, and genetic analysis of Mycobacterium tuberculosis urease, a potentially critical determinant of host-pathogen interaction. J. Bacteriol. 177, 5644-5652 (1995).
-
(1995)
J. Bacteriol.
, vol.177
, pp. 5644-5652
-
-
Clemens, D.L.1
Lee, B.Y.2
Horwitz, M.A.3
-
43
-
-
0034255209
-
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
-
Nathan, C. & Shiloh, M. U. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc. Natl Acad. Sci. USA 97, 8841-8848 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 8841-8848
-
-
Nathan, C.1
Shiloh, M.U.2
-
44
-
-
84884188211
-
Haemoglobins of mycobacteria: Structural features and biological functions
-
Davidge, K. S. & Dikshit, K. L. Haemoglobins of mycobacteria: structural features and biological functions. Adv. Microb. Physiol. 63, 147-194 (2013).
-
(2013)
Adv. Microb. Physiol.
, vol.63
, pp. 147-194
-
-
Davidge, K.S.1
Dikshit, K.L.2
-
45
-
-
84887276558
-
Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression
-
Cunningham-Bussel, A., Zhang, T. & Nathan, C. F. Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression. Proc. Natl Acad. Sci. USA 110, E4256-E4265 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. E4256-E4265
-
-
Cunningham-Bussel, A.1
Zhang, T.2
Nathan, C.F.3
-
46
-
-
84884258229
-
The intracellular environment of human macrophages that produce nitric oxide promotes growth of mycobacteria
-
Jung, J. Y. et al. The intracellular environment of human macrophages that produce nitric oxide promotes growth of mycobacteria. Infect. Immun. 81, 3198-3209 (2013).
-
(2013)
Infect. Immun.
, vol.81
, pp. 3198-3209
-
-
Jung, J.Y.1
-
47
-
-
37849036848
-
Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes
-
Davis, A. S. et al. Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes. PLoS Pathog. 3, e186 (2007).
-
(2007)
PLoS Pathog.
, vol.3
, pp. e186
-
-
Davis, A.S.1
-
48
-
-
0031010661
-
Identification of nitric oxide synthase as a protective locus against tuberculosis
-
MacMicking, J. D. et al. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl Acad. Sci. USA 94, 5243-5248 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 5243-5248
-
-
Macmicking, J.D.1
-
49
-
-
33750503812
-
Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice
-
Aly, S. et al. Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. J. Pathol. 210, 298-305 (2006).
-
(2006)
J. Pathol.
, vol.210
, pp. 298-305
-
-
Aly, S.1
-
50
-
-
79955801104
-
1H NMR-based metabolomic profiling in mice infected with Mycobacterium tuberculosis
-
1H NMR-based metabolomic profiling in mice infected with Mycobacterium tuberculosis. J. Proteome Res. 10, 2238-2247 (2011).
-
(2011)
J. Proteome Res.
, vol.10
, pp. 2238-2247
-
-
Shin, J.H.1
-
51
-
-
80052496075
-
1H magic angle spinning NMR studies
-
1H magic angle spinning NMR studies. J. Proteome Res. 10, 4186-4195 (2011).
-
(2011)
J. Proteome Res.
, vol.10
, pp. 4186-4195
-
-
Somashekar, B.S.1
-
52
-
-
84883173541
-
13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis
-
13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis. Chem. Biol. 20, 1012-1021 (2013).
-
(2013)
Chem. Biol.
, vol.20
, pp. 1012-1021
-
-
Beste, D.J.1
-
53
-
-
0035931926
-
Massive gene decay in the leprosy bacillus
-
Cole, S. T. et al. Massive gene decay in the leprosy bacillus. Nature 409, 1007-1011 (2001).
-
(2001)
Nature
, vol.409
, pp. 1007-1011
-
-
Cole, S.T.1
-
54
-
-
84905719886
-
Survival of mycobacteria depends on proteasome-mediated amino acid recycling under nutrient limitation
-
Elharar, Y. et al. Survival of mycobacteria depends on proteasome-mediated amino acid recycling under nutrient limitation. EMBO J. 33, 1802-1814 (2014).
-
(2014)
EMBO J.
, vol.33
, pp. 1802-1814
-
-
Elharar, Y.1
-
55
-
-
77958132278
-
The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide
-
Gandotra, S., Lebron, M. B. & Ehrt, S. The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide. PLoS Pathog. 6, e1001040 (2010).
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1001040
-
-
Gandotra, S.1
Lebron, M.B.2
Ehrt, S.3
-
56
-
-
0037022296
-
Human macrophage activation programs induced by bacterial pathogens
-
Nau, G. J. et al. Human macrophage activation programs induced by bacterial pathogens. Proc. Natl Acad. Sci. USA 99, 1503-1508 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 1503-1508
-
-
Nau, G.J.1
-
57
-
-
38849177346
-
Probing host pathogen crosstalk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages
-
Tailleux, L. et al. Probing host pathogen crosstalk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages. PLoS ONE 3, e1403 (2008).
-
(2008)
PLoS ONE
, vol.3
, pp. e1403
-
-
Tailleux, L.1
-
58
-
-
84863810737
-
Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome
-
Campbell-Valois, F. X. et al. Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome. Mol Cell Proteomics 11, M111016378 (2012).
-
(2012)
Mol Cell Proteomics
, vol.11
, pp. M111016378
-
-
Campbell-Valois, F.X.1
-
59
-
-
84867632839
-
Francisella tularensis regulates the expression of the amino acid transporter SLC1A5 in infected THP-1 human monocytes
-
Barel, M., Meibom, K., Dubail, I., Botella, J. & Charbit, A. Francisella tularensis regulates the expression of the amino acid transporter SLC1A5 in infected THP-1 human monocytes. Cell. Microbiol. 14, 1769-1783 (2012).
-
(2012)
Cell. Microbiol.
, vol.14
, pp. 1769-1783
-
-
Barel, M.1
Meibom, K.2
Dubail, I.3
Botella, J.4
Charbit, A.5
-
60
-
-
14844304337
-
Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5
-
Wieland, H., Ullrich, S., Lang, F. & Neumeister, B. Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5. Mol. Microbiol. 55, 1528-1537 (2005).
-
(2005)
Mol. Microbiol.
, vol.55
, pp. 1528-1537
-
-
Wieland, H.1
Ullrich, S.2
Lang, F.3
Neumeister, B.4
-
61
-
-
78649977572
-
Cationic amino acid transporters and Salmonella Typhimurium ArgT collectively regulate arginine availability towards intracellular Salmonella growth
-
Das, P. et al. Cationic amino acid transporters and Salmonella Typhimurium ArgT collectively regulate arginine availability towards intracellular Salmonella growth. PLoS ONE 5, e15466 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e15466
-
-
Das, P.1
-
62
-
-
33745436997
-
Arginine homeostasis in J774.1 macrophages in the context of Mycobacterium bovis BCG infection
-
Talaue, M. T. et al. Arginine homeostasis in J774.1 macrophages in the context of Mycobacterium bovis BCG infection. J. Bacteriol. 188, 4830-4840 (2006).
-
(2006)
J. Bacteriol.
, vol.188
, pp. 4830-4840
-
-
Talaue, M.T.1
-
63
-
-
84866434542
-
Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1
-
Qualls, J. E. et al. Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1. Cell Host Microbe 12, 313-323 (2012).
-
(2012)
Cell Host Microbe
, vol.12
, pp. 313-323
-
-
Qualls, J.E.1
-
64
-
-
84890037649
-
Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing
-
Zhang, Y. J. et al. Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing. Cell 155, 1296-1308 (2013).
-
(2013)
Cell
, vol.155
, pp. 1296-1308
-
-
Zhang, Y.J.1
-
65
-
-
79959463532
-
Tryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense
-
Chu, P., Rodriguez, A. R., Arulanandam, B. P. & Klose, K. E. Tryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense. Infect. Immun. 79, 2356-2361 (2011).
-
(2011)
Infect. Immun.
, vol.79
, pp. 2356-2361
-
-
Chu, P.1
Rodriguez, A.R.2
Arulanandam, B.P.3
Klose, K.E.4
-
66
-
-
34250716965
-
M. Tuberculosi s and M. Lepra e translocate from the phagolysosome to the cytosol in myeloid cells
-
van der Wel, N. et al. M. tuberculosi s and M. lepra e translocate from the phagolysosome to the cytosol in myeloid cells. Cell 129, 1287-1298 (2007).
-
(2007)
Cell
, vol.129
, pp. 1287-1298
-
-
Van Der Wel, N.1
-
67
-
-
84864330080
-
Toward a systemic understanding of Listeria monocytogenes metabolism during infection
-
Fuchs, T. M., Eisenreich, W., Kern, T. & Dandekar, T. Toward a systemic understanding of Listeria monocytogenes metabolism during infection. Front. Microbiol. 3, 23 (2012).
-
(2012)
Front. Microbiol.
, vol.3
, pp. 23
-
-
Fuchs, T.M.1
Eisenreich, W.2
Kern, T.3
Dandekar, T.4
-
68
-
-
84883401064
-
Francisella tularensis harvests nutrients derived via ATG5-independent autophagy to support intracellular growth
-
Steele, S. et al. Francisella tularensis harvests nutrients derived via ATG5-independent autophagy to support intracellular growth. PLoS Pathog. 9, e1003562 (2013).
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003562
-
-
Steele, S.1
-
69
-
-
84881547839
-
Autophagy as an immune effector against tuberculosis
-
Bradfute, S. B. et al. Autophagy as an immune effector against tuberculosis. Curr. Opin. Microbiol. 16, 355-365 (2013).
-
(2013)
Curr. Opin. Microbiol.
, vol.16
, pp. 355-365
-
-
Bradfute, S.B.1
-
70
-
-
47249147003
-
Functional analysis of GlnE, an essential adenylyl transferase in Mycobacterium tuberculosis
-
Carroll, P., Pashley, C. A. & Parish, T. Functional analysis of GlnE, an essential adenylyl transferase in Mycobacterium tuberculosis. J. Bacteriol. 190, 4894-4902 (2008).
-
(2008)
J. Bacteriol.
, vol.190
, pp. 4894-4902
-
-
Carroll, P.1
Pashley, C.A.2
Parish, T.3
-
71
-
-
70349420809
-
Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors
-
Nilsson, M. T. et al. Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors. J. Mol. Biol. 393, 504-513 (2009).
-
(2009)
J. Mol. Biol.
, vol.393
, pp. 504-513
-
-
Nilsson, M.T.1
-
72
-
-
77049156477
-
Studies on the metabolism of Mycobacterium tuberculosis. II. The effect of compounds related to the Kreb's tricarboxylic acid cycle on the growth of Mycobacterium tuberculosis var. Hominis
-
Youmans, A. S. & Youmans, G. P. Studies on the metabolism of Mycobacterium tuberculosis. II. The effect of compounds related to the Kreb's tricarboxylic acid cycle on the growth of Mycobacterium tuberculosis var. hominis. J. Bacteriol. 65, 96-99 (1953).
-
(1953)
J. Bacteriol.
, vol.65
, pp. 96-99
-
-
Youmans, A.S.1
Youmans, G.P.2
-
73
-
-
41949119272
-
Mycobacterial persistence requires the utilization of host cholesterol
-
Pandey, A. K. & Sassetti, C. M. Mycobacterial persistence requires the utilization of host cholesterol. Proc. Natl Acad. Sci. USA 105, 4376-4380 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4376-4380
-
-
Pandey, A.K.1
Sassetti, C.M.2
-
74
-
-
79959815079
-
Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages
-
Daniel, J., Maamar, H., Deb, C., Sirakova, T. D. & Kolattukudy, P. E. Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages. PLoS Pathog. 7, e1002093 (2011).
-
(2011)
PLoS Pathog.
, vol.7
, pp. e1002093
-
-
Daniel, J.1
Maamar, H.2
Deb, C.3
Sirakova, T.D.4
Kolattukudy, P.E.5
-
75
-
-
84893020254
-
Reversible lipid accumulation and associated division arrest of Mycobacterium avium in lipoprotein-induced foamy macrophages may resemble key events during latency and reactivation of tuberculosis
-
Caire-Brandli, I. et al. Reversible lipid accumulation and associated division arrest of Mycobacterium avium in lipoprotein-induced foamy macrophages may resemble key events during latency and reactivation of tuberculosis. Infect. Immun. 82, 476-490 (2014).
-
(2014)
Infect. Immun.
, vol.82
, pp. 476-490
-
-
Caire-Brandli, I.1
-
76
-
-
57149096869
-
Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. Tuberculosi s persistence
-
Peyron, P. et al. Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosi s persistence. PLoS Pathog. 4, e1000204 (2008).
-
(2008)
PLoS Pathog.
, vol.4
, pp. e1000204
-
-
Peyron, P.1
-
77
-
-
69049108875
-
Foamy macrophages and the progression of the human tuberculosis granuloma
-
Russell, D. G., Cardona, P. J., Kim, M. J., Allain, S. & Altare, F. Foamy macrophages and the progression of the human tuberculosis granuloma. Nature Immunol. 10, 943-948 (2009).
-
(2009)
Nature Immunol.
, vol.10
, pp. 943-948
-
-
Russell, D.G.1
Cardona, P.J.2
Kim, M.J.3
Allain, S.4
Altare, F.5
-
78
-
-
84869176200
-
Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype
-
Singh, V. et al. Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype. Cell Host Microbe 12, 669-681 (2012).
-
(2012)
Cell Host Microbe
, vol.12
, pp. 669-681
-
-
Singh, V.1
-
79
-
-
84875071289
-
Glucose phosphorylation is required for Mycobacterium tuberculosis persistence in mice
-
Marrero, J., Trujillo, C., Rhee, K. Y. & Ehrt, S. Glucose phosphorylation is required for Mycobacterium tuberculosis persistence in mice. PLoS Pathog. 9, e1003116 (2013).
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003116
-
-
Marrero, J.1
Trujillo, C.2
Rhee, K.Y.3
Ehrt, S.4
-
80
-
-
79959913123
-
Central carbon metabolism in Mycobacterium tuberculosis: An unexpected frontier
-
Rhee, K. Y. et al. Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier. Trends Microbiol. 19, 307-314 (2011).
-
(2011)
Trends Microbiol.
, vol.19
, pp. 307-314
-
-
Rhee, K.Y.1
-
81
-
-
79960933284
-
13C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation
-
13C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation. PLoS Pathog. 7, e1002091 (2011).
-
(2011)
PLoS Pathog.
, vol.7
, pp. e1002091
-
-
Beste, D.J.1
-
82
-
-
84889092846
-
Francisella tularensis intracellular survival: To eat or to die
-
Barel, M. & Charbit, A. Francisella tularensis intracellular survival: to eat or to die. Microbes Infect. (2013).
-
(2013)
Microbes Infect.
-
-
Barel, M.1
Charbit, A.2
-
83
-
-
84893862884
-
Asparagine assimilation is critical for intracellular replication and dissemination of Francisella
-
Gesbert, G. et al. Asparagine assimilation is critical for intracellular replication and dissemination of Francisella. Cell. Microbiol. (2013).
-
(2013)
Cell. Microbiol.
-
-
Gesbert, G.1
-
84
-
-
22244434967
-
The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages
-
Sauer, J. D., Bachman, M. A. & Swanson, M. S. The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages. Proc. Natl Acad. Sci. USA 102, 9924-9929 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 9924-9929
-
-
Sauer, J.D.1
Bachman, M.A.2
Swanson, M.S.3
-
85
-
-
83855160757
-
Host proteasomal degradation generates amino acids essential for intracellular bacterial growth
-
Price, C. T., Al-Quadan, T., Santic, M., Rosenshine, I. & Abu Kwaik, Y. Host proteasomal degradation generates amino acids essential for intracellular bacterial growth. Science 334, 1553-1557 (2011).
-
(2011)
Science
, vol.334
, pp. 1553-1557
-
-
Price, C.T.1
Al-Quadan, T.2
Santic, M.3
Rosenshine, I.4
Abu Kwaik, Y.5
|