The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide

PLoS Pathogens

Volumn 6, Issue 8, 2010, Pages 25-26

  Gandotra, Sheetal ^a   Lebron, Maria B ^a   Ehrt, Sabine ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROTEASOME; THREONINE; BACTERIAL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; FEMALE; IMMUNE DEFICIENCY; IMMUNOCOMPETENCE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRCB GENE; PRCBA GENE; TUBERCULOSIS; ANIMAL; C57BL MOUSE; CHEMISTRY; ENZYME ACTIVE SITE; GENE INACTIVATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOBLOTTING; METABOLISM; MUTATION; PATHOGENICITY; POLYMERASE CHAIN REACTION;

BACILLI (CLASS); MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; FEMALE; GENE KNOCKOUT TECHNIQUES; IMMUNOBLOTTING; MICE; MICE, INBRED C57BL; MUTATION; MYCOBACTERIUM TUBERCULOSIS; NITRIC OXIDE; POLYMERASE CHAIN REACTION; PROTEASOME ENDOPEPTIDASE COMPLEX; THREONINE; TUBERCULOSIS;

EID: 77958132278     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001040     Document Type: Article

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