Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions

Journal of Molecular Biology

Volumn 350, Issue 5, 2005, Pages 953-963

  Villarino, A ^a   Duran, R ^b   Wehenkel, A ^a   Fernandez, P ^a   England, P ^a   Brodin, P ^a   Cole, S T ^a   Zimny Arndt, U ^c   Jungblut, P R ^c   Cervenansky C ^b   Alzari, P M ^a  

^a INSTITUT PASTEUR   (France)

^b INSTITUTO DE INVESTIGACIONES BIOLÓGICAS CLEMENTE ESTABLE   (Uruguay)

^c MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

Activation loop; Forkhead associated domain; GarA (Rv1827); Ser Thr protein kinase; Substrate docking

Indexed keywords

BACTERIAL PROTEIN; DOCKING PROTEIN; PROTEIN; PROTEIN GARA; PROTEIN PKNB; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ACTINOBACTERIA; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL CELL; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR MODEL; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEOMICS; SIGNAL TRANSDUCTION;

CORYNEBACTERINEAE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA;

EID: 20744445530     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.05.049     Document Type: Article

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