DNA methylation analysis of human myoblasts during in vitro myogenic differentiation: De novo methylation of promoters of muscle-related genes and its involvement in transcriptional down-regulation

Human Molecular Genetics

Volumn 24, Issue 2, 2015, Pages 410-423

  Miyata, Kohei ^a,b   Miyata, Tomoko ^a,c   Nakabayashi, Kazuhiko ^a   Okamura, Kohji ^a   Naito, Masashi ^d   Kawai, Tomoko ^a   Takada, Shuji ^a   Kato, Kiyoko ^c   Miyamoto, Shingo ^b   Hata, Kenichiro ^a   Asahara, Hiroshi ^a,d,e  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CPG ISLAND; DEVELOPMENTAL GENE; DNA FLANKING REGION; DNA METHYLATION; DNA MICROARRAY; DNA SEQUENCE; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE ONTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL; MUSCLE DEVELOPMENT; MYOBLAST; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; CELL CULTURE; CYTOLOGY; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; SKELETAL MUSCLE;

ID4 PROTEIN, HUMAN; INHIBITOR OF DIFFERENTIATION PROTEIN; REPRESSOR PROTEIN; ZNF238 PROTEIN, HUMAN;

CELLS, CULTURED; DNA METHYLATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEINS; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; MYOBLASTS; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84922463818     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu457     Document Type: Article

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