Cathepsin B regulates the appearance and severity of mercury-induced inflammation and autoimmunity

Toxicological Sciences

Volumn 142, Issue 2, 2014, Pages 339-349

  Toomey, Christopher B ^a   Cauvi, David M ^b   Hamel, John C ^c   Ramirez, Andrea E ^c   Michael Pollard, K ^c  

^a DUKE UNIVERSITY EYE CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Autoimmunity; Cathepsin B; Cytokines; Inflammation; Mercuric chloride; T cell activation

Indexed keywords

AUTOANTIBODY; CATHEPSIN B; CATHEPSIN L; CATHEPSIN S; CRYOPYRIN; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; INFLAMMASOME; INTERLEUKIN 1BETA; MERCURY; MERCURY CHLORIDE; N (3 PROPYLCARBAMOYLOXIRANE 2 CARBONYL)ISOLEUCYLPROLINE; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL MARKER; CYTOKINE; DIPEPTIDE; MERCURIC CHLORIDE; N-(3-PROPYLCARBAMOYLOXIRANE-2-CARBONYL)-ISOLEUCYL-PROLINE;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; EXPOSURE; HYPERGAMMAGLOBULINEMIA; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; MERCURY INDUCED AUTOIMMUNITY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; SKIN; SKIN INDURATION; SPLENOMEGALY; T LYMPHOCYTE ACTIVATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CYTOLOGY; DERMATITIS; DISEASE PREDISPOSITION; DRUG EFFECTS; ENZYMOLOGY; GENETICS; IMMUNOLOGY; INBRED MOUSE STRAIN; METABOLISM; SPLEEN; T LYMPHOCYTE;

MURINAE; MUS;

ANIMALS; AUTOIMMUNITY; BIOMARKERS; CATHEPSIN B; CYTOKINES; DERMATITIS; DIPEPTIDES; DISEASE SUSCEPTIBILITY; IMMUNOGLOBULIN G; MERCURIC CHLORIDE; MICE; MICE, INBRED STRAINS; SKIN; SPLEEN; T-LYMPHOCYTES;

EID: 84922459223     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu189     Document Type: Article

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