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Volumn 5, Issue 10, 2014, Pages

Caspase-9 mediates Puma activation in UCN-01-induced apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

7 HYDROXYSTAUROSPORINE; CASPASE 3; CASPASE 9; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PUMA PROTEIN; TRANSCRIPTION FACTOR FKHRL1; X LINKED INHIBITOR OF APOPTOSIS; 7-HYDROXYSTAUROSPORINE; APOPTOSIS REGULATORY PROTEIN; BBC3 PROTEIN, HUMAN; DIABLO PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; ONCOPROTEIN; PROTEIN BCL X; PROTEIN P53; PUMA PROTEIN, MOUSE; SIGNAL PEPTIDE; STAUROSPORINE; TUMOR SUPPRESSOR PROTEIN;

EID: 84922434956     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.461     Document Type: Article
Times cited : (27)

References (32)
  • 1
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams JM, Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 2007; 26: 1324-1337.
    • (2007) Oncogene , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0345256652 scopus 로고    scopus 로고
    • Cisplatin: Mode of cytotoxic action and molecular basis of resistance
    • Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003; 22: 7265-7279.
    • (2003) Oncogene , vol.22 , pp. 7265-7279
    • Siddik, Z.H.1
  • 3
    • 33947324515 scopus 로고    scopus 로고
    • Absence of Bcl-xL downregulation in response to cisplatin is associated with chemoresistance in ovarian carcinoma cells
    • Villedieu M, Louis MH, Dutoit S, Brotin E, Lincet H, Duigou F et al. Absence of Bcl-xL downregulation in response to cisplatin is associated with chemoresistance in ovarian carcinoma cells. Gynecol Oncol 2007; 105: 31-44.
    • (2007) Gynecol Oncol , vol.105 , pp. 31-44
    • Villedieu, M.1    Louis, M.H.2    Dutoit, S.3    Brotin, E.4    Lincet, H.5    Duigou, F.6
  • 6
    • 34250880206 scopus 로고    scopus 로고
    • SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events.
    • Yu J, Wang P, Ming L, Wood MA, Zhang L. SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events. Oncogene 2007; 26: 4189-4198.
    • (2007) Oncogene , vol.26 , pp. 4189-4198
    • Yu, J.1    Wang, P.2    Ming, L.3    Wood, M.A.4    Zhang, L.5
  • 7
    • 84860847695 scopus 로고    scopus 로고
    • JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells
    • Zhao Z, Wang J, Tang J, Liu X, Zhong Q, Wang F et al. JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells. Biochem J 2012; 444: 291-301.
    • (2012) Biochem J , vol.444 , pp. 291-301
    • Zhao, Z.1    Wang, J.2    Tang, J.3    Liu, X.4    Zhong, Q.5    Wang, F.6
  • 8
    • 82855168143 scopus 로고    scopus 로고
    • The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1.
    • Yuan Z, Cao K, Lin C, Li L, Liu HY, Zhao XY et al. The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1. Mol Med 2011; 17: 1262-1274.
    • (2011) Mol Med , vol.17 , pp. 1262-1274
    • Yuan, Z.1    Cao, K.2    Lin, C.3    Li, L.4    Liu, H.Y.5    Zhao, X.Y.6
  • 9
    • 34247481285 scopus 로고    scopus 로고
    • Targeting checkpoint kinase 1 in cancer therapeutics
    • Tse AN, Carvajal R, Schwartz GK. Targeting checkpoint kinase 1 in cancer therapeutics. Clin Cancer Res 2007; 13: 1955-1960.
    • (2007) Clin Cancer Res , vol.13 , pp. 1955-1960
    • Tse, A.N.1    Carvajal, R.2    Schwartz, G.K.3
  • 10
    • 0024916449 scopus 로고
    • Evolution of family policy in the light of demographic development in West European countries
    • Gilliand P. Evolution of family policy in the light of demographic development in West European countries. Int Soc Secur Rev 1989; 42: 395-426.
    • (1989) Int Soc Secur Rev , vol.42 , pp. 395-426
    • Gilliand, P.1
  • 11
    • 0034655281 scopus 로고    scopus 로고
    • The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1
    • Busby EC, Leistritz DF, Abraham RT, Karnitz LM, Sarkaria JN. The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. Cancer Res 2000; 60: 2108-2112.
    • (2000) Cancer Res , vol.60 , pp. 2108-2112
    • Busby, E.C.1    Leistritz, D.F.2    Abraham, R.T.3    Karnitz, L.M.4    Sarkaria, J.N.5
  • 12
    • 0042441979 scopus 로고    scopus 로고
    • Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKTrelated pathways
    • Jia W, Yu C, Rahmani M, Krystal G, Sausville EA, Dent P et al. Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKTrelated pathways. Blood 2003; 102: 1824-1832.
    • (2003) Blood , vol.102 , pp. 1824-1832
    • Jia, W.1    Yu, C.2    Rahmani, M.3    Krystal, G.4    Sausville, E.A.5    Dent, P.6
  • 13
    • 3042531148 scopus 로고    scopus 로고
    • Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: A potential target for UCN-01
    • Amornphimoltham P, Sriuranpong V, Patel V, Benavides F, Conti CJ, Sauk J et al. Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01. Clin Cancer Res 2004; 10(Part 1): 4029-4037.
    • (2004) Clin Cancer Res , vol.10 , pp. 4029-4037
    • Amornphimoltham, P.1    Sriuranpong, V.2    Patel, V.3    Benavides, F.4    Conti, C.J.5    Sauk, J.6
  • 14
    • 0036729867 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy
    • Krystal GW, Sulanke G, Litz J. Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy. Mol Cancer Ther 2002; 1: 913-922.
    • (2002) Mol Cancer Ther , vol.1 , pp. 913-922
    • Krystal, G.W.1    Sulanke, G.2    Litz, J.3
  • 15
    • 34548821574 scopus 로고    scopus 로고
    • MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism.
    • Pei XY, Dai Y, Tenorio S, Lu J, Harada H, Dent P et al. MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism. Blood 2007; 110: 2092-2101.
    • (2007) Blood , vol.110 , pp. 2092-2101
    • Pei, X.Y.1    Dai, Y.2    Tenorio, S.3    Lu, J.4    Harada, H.5    Dent, P.6
  • 16
    • 19944432818 scopus 로고    scopus 로고
    • The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein
    • Bhonde MR, Hanski ML, Magrini R, Moorthy D, Muller A, Sausville EA et al. The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein. Oncogene 2005; 24: 148-156.
    • (2005) Oncogene , vol.24 , pp. 148-156
    • Bhonde, M.R.1    Hanski, M.L.2    Magrini, R.3    Moorthy, D.4    Muller, A.5    Sausville, E.A.6
  • 17
    • 0034662619 scopus 로고    scopus 로고
    • Caspase-3 is essential for procaspase-9 processing and cisplatin-induced apoptosis of MCF-7 breast cancer cells
    • Blanc C, Deveraux QL, Krajewski S, Janicke RU, Porter AG, Reed JC et al. Caspase-3 is essential for procaspase-9 processing and cisplatin-induced apoptosis of MCF-7 breast cancer cells. Cancer Res 2000; 60: 4386-4390.
    • (2000) Cancer Res , vol.60 , pp. 4386-4390
    • Blanc, C.1    Deveraux, Q.L.2    Krajewski, S.3    Janicke, R.U.4    Porter, A.G.5    Reed, J.C.6
  • 18
    • 80052666457 scopus 로고    scopus 로고
    • Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: Activation of caspase- 9 in the absence of Apaf-1
    • Manns J, Daubrawa M, Driessen S, Paasch F, Hoffmann N, Loffler A et al. Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase- 9 in the absence of Apaf-1. FASEB J 2011; 25: 3250-3261.
    • (2011) FASEB J , vol.25 , pp. 3250-3261
    • Manns, J.1    Daubrawa, M.2    Driessen, S.3    Paasch, F.4    Hoffmann, N.5    Loffler, A.6
  • 19
    • 0033601746 scopus 로고    scopus 로고
    • Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
    • Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD et al. Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J Cell Biol 1999; 144: 281-292.
    • (1999) J Cell Biol , vol.144 , pp. 281-292
    • Slee, E.A.1    Harte, M.T.2    Kluck, R.M.3    Wolf, B.B.4    Casiano, C.A.5    Newmeyer, D.D.6
  • 20
    • 36348934636 scopus 로고    scopus 로고
    • Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members
    • Chen M, Guerrero AD, Huang L, Shabier Z, Pan M, Tan TH et al. Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members. J Biol Chem 2007; 282: 33888-33895.
    • (2007) J Biol Chem , vol.282 , pp. 33888-33895
    • Chen, M.1    Guerrero, A.D.2    Huang, L.3    Shabier, Z.4    Pan M.Tan, T.H.5
  • 22
    • 0032473496 scopus 로고    scopus 로고
    • Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: Evidence for a caspase-mediated, proteolytic inactivation of Bcl-2
    • Grandgirard D, Studer E, Monney L, Belser T, Fellay I, Borner C et al. Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2. EMBO J 1998; 17: 1268-1278.
    • (1998) EMBO J , vol.17 , pp. 1268-1278
    • Grandgirard, D.1    Studer, E.2    Monney, L.3    Belser, T.4    Fellay, I.5    Borner, C.6
  • 23
    • 79551632028 scopus 로고    scopus 로고
    • Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis
    • Hornle M, Peters N, Thayaparasingham B, Vorsmann H, Kashkar H, Kulms D. Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis. Oncogene 2011; 30: 575-587.
    • (2011) Oncogene , vol.30 , pp. 575-587
    • Hornle, M.1    Peters, N.2    Thayaparasingham, B.3    Vorsmann, H.4    Kashkar, H.5    Kulms, D.6
  • 24
    • 0035282570 scopus 로고    scopus 로고
    • A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
    • Srinivasula SM, Hegde R, Saleh A, Datta P, Shiozaki E, Chai J et al. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature 2001; 410: 112-116.
    • (2001) Nature , vol.410 , pp. 112-116
    • Srinivasula, S.M.1    Hegde, R.2    Saleh, A.3    Datta, P.4    Shiozaki, E.5    Chai, J.6
  • 25
    • 78649684224 scopus 로고    scopus 로고
    • PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01
    • Dudgeon C,Wang P, Sun X, Peng R, Sun Q, Yu J et al. PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01. Mol Cancer Ther 2010; 9: 2893-2902.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2893-2902
    • Dudgeon, C.1    Wang, P.2    Sun, X.3    Peng, R.4    Sun, Q.5    Yu, J.6
  • 26
    • 0031213555 scopus 로고    scopus 로고
    • 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53
    • Shao RG, Shimizu T, Pommier Y. 7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53. Exp Cell Res 1997; 234: 388-397.
    • (1997) Exp Cell Res , vol.234 , pp. 388-397
    • Shao, R.G.1    Shimizu, T.2    Pommier, Y.3
  • 27
    • 33744942924 scopus 로고    scopus 로고
    • PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
    • Ming L, Wang P, Bank A, Yu J, Zhang L. PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells. J Biol Chem 2006; 281: 16034-16042.
    • (2006) J Biol Chem , vol.281 , pp. 16034-16042
    • Ming, L.1    Wang, P.2    Bank, A.3    Yu, J.4    Zhang, L.5
  • 29
    • 58149101589 scopus 로고    scopus 로고
    • Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells
    • Shawgo ME, Shelton SN, Robertson JD. Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells. J Biol Chem 2008; 283: 35532-35538.
    • (2008) J Biol Chem , vol.283 , pp. 35532-35538
    • Shawgo, M.E.1    Shelton, S.N.2    Robertson, J.D.3
  • 30
    • 84855293917 scopus 로고    scopus 로고
    • Proapoptotic protein Smac mediates apoptosis in cisplatin-resistant ovarian cancer cells when treated with the anti-tumor agent AT101
    • Hu W, Wang F, Tang J, Liu X, Yuan Z, Nie C et al. Proapoptotic protein Smac mediates apoptosis in cisplatin-resistant ovarian cancer cells when treated with the anti-tumor agent AT101. J Biol Chem 2012; 287: 68-80.
    • (2012) J Biol Chem , vol.287 , pp. 68-80
    • Hu, W.1    Wang, F.2    Tang, J.3    Liu, X.4    Yuan, Z.5    Nie, C.6
  • 31
    • 79957851071 scopus 로고    scopus 로고
    • BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.
    • Yuan Z, Wang F, Zhao Z, Zhao X, Qiu J, Nie C et al. BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells. PLoS One 2011; 6: e20586.
    • (2011) PLoS One , vol.6 , pp. e20586
    • Yuan, Z.1    Wang, F.2    Zhao, Z.3    Zhao, X.4    Qiu, J.5    Nie, C.6
  • 32
    • 84897448414 scopus 로고    scopus 로고
    • SKLB-163, a new benzothiazole-2-thiol derivative, exhibits potent anticancer activity by affecting RhoGDI/JNK-1 signaling pathway
    • Peng X, Xie G, Wang Z, Lin H, Zhou T, Xiang P et al. SKLB-163, a new benzothiazole-2-thiol derivative, exhibits potent anticancer activity by affecting RhoGDI/JNK-1 signaling pathway. Cell Death Dis 2014; 5: e1143.
    • (2014) Cell Death Dis , vol.5 , pp. e1143
    • Peng, X.1    Xie, G.2    Wang, Z.3    Lin, H.4    Zhou, T.5    Xiang, P.6


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