Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture

Journal of Neurochemistry

Volumn 131, Issue 4, 2014, Pages 498-508

  Han, Zhenying ^a,b   Li, Li ^a   Wang, Liang ^a   Degos, Vincent ^a,c   Maze, Mervyn ^a   Su, Hua ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c HÔPITAL ROBERT DEBRÉ   (France)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

macrophage polarization; middle cerebral artery occlusion; neuroinflammation; oxidative stress

Indexed keywords

BUNGAROTOXIN RECEPTOR; CD68 ANTIGEN; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHYLLYCACONITINE; NICOTINIC AGENT; PHA 568487; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; CYTOKINE; DIOXIN; ENOLASE; HETEROCYCLIC COMPOUND; PHA-568487E; SUPEROXIDE DISMUTASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EXPERIMENTAL BEHAVIORAL TEST; GENE EXPRESSION REGULATION; GPX1 GENE; INHIBITION KINETICS; MACROPHAGE; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SOD1 GENE; TIBIA FRACTURE; UPREGULATION; AGONISTS; ANIMAL; BRAIN INFARCTION; BRAIN INJURIES; C57BL MOUSE; CEREBRAL ARTERY DISEASE; COMPLICATION; DRUG EFFECTS; ENCEPHALITIS; FRACTURE; METABOLISM; NICK END LABELING; PSYCHOMOTOR PERFORMANCE;

MUS;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; AZA COMPOUNDS; BRAIN INFARCTION; BRAIN INJURIES; CYTOKINES; DIOXINS; ENCEPHALITIS; FRACTURES, BONE; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; NICOTINIC AGONISTS; OXIDATIVE STRESS; PHOSPHOPYRUVATE HYDRATASE; PSYCHOMOTOR PERFORMANCE; SUPEROXIDE DISMUTASE;

EID: 84922395259     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12817     Document Type: Article

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