Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: Is smoking reduced or nicotine-free products really safe?

BMC Neuroscience

Volumn 15, Issue , 2014, Pages

  Naik, Pooja ^a   Fofaria, Neel ^a   Prasad, Shikha ^a   Sajja, Ravi K ^a   Weksler, Babette ^b   Couraud, Pierre Olivier ^c,d,e   Romero, Ignacio A ^f   Cucullo, Luca ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c INSTITUT COCHIN   (France)

^d CNRS   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f OPEN UNIVERSITY   (United Kingdom)

Author keywords

Blood brain barrier; In vitro; Inflammation; Nicotine; Nicotine Free; Oxidative stress; Permeability; Smoking; Tobacco; Ultralow nicotine, alternative

Indexed keywords

CD31 ANTIGEN; CIGARETTE SMOKE; CLAUDIN 5; GELATINASE A; HYDROGEN PEROXIDE; INTERLEUKIN 6; NICOTINE; NITRATE; NITRITE; OCCLUDIN; PROTEIN ZO1; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TAR; TIGHT JUNCTION PROTEIN; VASCULAR CELL ADHESION MOLECULE 1; VASCULAR ENDOTHELIAL CADHERIN; AUTACOID;

ACTIN FILAMENT; ARTICLE; BLOOD BRAIN BARRIER; CELL DAMAGE; CELL MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; FLAVOR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INFLAMMATION; MICROVASCULAR ENDOTHELIAL CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; SMOKING; TOBACCO; UPREGULATION; ANALYSIS; CELL LINE; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SMOKING CESSATION;

BLOOD-BRAIN BARRIER; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; NICOTINE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SMOKING CESSATION; TOBACCO PRODUCTS;

EID: 84900399375     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-15-51     Document Type: Article

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