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Volumn 43, Issue 3, 2012, Pages 844-850

α7 nicotinic acetylcholine receptor agonism confers neuroprotection through GSK-3β inhibition in a mouse model of intracerebral hemorrhage

Author keywords

7 nicotinic acetylcholine receptor; apoptosis; caspase 3; glycogen synthase kinase 3; intracerebral hemorrhage; PHA 282987; PHA 543613

Indexed keywords

4 CHLORO N (3 QUINUCLIDINYL)BENZAMIDE; CASPASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; METHYLLYCACONITINE; N (3 QUINUCLIDINYL)FURO[2,3 C]PYRIDINE 5 CARBOXAMIDE; NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA 7; NICOTINIC RECEPTOR; PROTEIN KINASE B; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 84857644494     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.639989     Document Type: Article
Times cited : (96)

References (33)
  • 1
    • 0029008248 scopus 로고
    • Intracerebral hemorrhage versus infarction: Stroke severity, risk factors, and prognosis
    • Jorgensen HS, Nakayama H, Raaschou HO, Olsen TS. Intracerebral hemorrhage versus infarction: stroke severity, risk factors, and prognosis. Ann Neurol. 1995;38:45-50.
    • (1995) Ann Neurol. , vol.38 , pp. 45-50
    • Jorgensen, H.S.1    Nakayama, H.2    Raaschou, H.O.3    Olsen, T.S.4
  • 2
    • 0027562635 scopus 로고
    • Hemorrhagic transformation after cerebral ischemia: Mechanisms and incidence
    • Lyden PD, Zivin JA. Hemorrhagic transformation after cerebral ischemia: mechanisms and incidence. Cerebrovasc Brain Metab Rev. 1993;5:1-16.
    • (1993) Cerebrovasc Brain Metab Rev. , vol.5 , pp. 1-16
    • Lyden, P.D.1    Zivin, J.A.2
  • 4
    • 17144403822 scopus 로고    scopus 로고
    • New horizons for primary intracerebral hemorrhage treatment: Experience from preclinical studies
    • Aronowski J, Hall CE. New horizons for primary intracerebral hemorrhage treatment: experience from preclinical studies. Neurol Res. 2005;27:268-279.
    • (2005) Neurol Res. , vol.27 , pp. 268-279
    • Aronowski, J.1    Hall, C.E.2
  • 6
    • 41249094915 scopus 로고    scopus 로고
    • Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators
    • Lightfoot AP, Kew JN, Skidmore J. Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators. Prog Med Chem. 2008;46:131-171.
    • (2008) Prog Med Chem. , vol.46 , pp. 131-171
    • Lightfoot, A.P.1    Kew, J.N.2    Skidmore, J.3
  • 7
    • 33747044365 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade
    • Takada-Takatori Y, Kume T, Sugimoto M, Katsuki H, Sugimoto H, Akaike A. Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade. Neuropharmacology. 2006;51:474-486.
    • (2006) Neuropharmacology. , vol.51 , pp. 474-486
    • Takada-Takatori, Y.1    Kume, T.2    Sugimoto, M.3    Katsuki, H.4    Sugimoto, H.5    Akaike, A.6
  • 8
    • 84856222572 scopus 로고    scopus 로고
    • α7 nicotinic acetylcholine receptor agonist pnu-282987 attenuates early brain injury in a perforation model of subarachnoid hemorrhage in rats
    • Duris K, Manaenko A, Suzuki H, Rolland WB, Krafft PR, Zhang JH. α7 nicotinic acetylcholine receptor agonist pnu-282987 attenuates early brain injury in a perforation model of subarachnoid hemorrhage in rats. Stroke. 2011;42:3530-3536.
    • (2011) Stroke , vol.42 , pp. 3530-3536
    • Duris, K.1    Manaenko, A.2    Suzuki, H.3    Rolland, W.B.4    Krafft, P.R.5    Zhang, J.H.6
  • 9
    • 0346460961 scopus 로고    scopus 로고
    • Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against a beta-(1-42) amyloid
    • Shaw S, Bencherif M, Marrero MB. Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against a beta-(1-42) amyloid. J Biol Chem. 2002;277:44920-44924.
    • (2002) J Biol Chem. , vol.277 , pp. 44920-44924
    • Shaw, S.1    Bencherif, M.2    Marrero, M.B.3
  • 10
    • 0034859101 scopus 로고    scopus 로고
    • The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
    • Grimes CA, Jope RS. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol. 2001;65:391-426.
    • (2001) Prog Neurobiol. , vol.65 , pp. 391-426
    • Grimes, C.A.1    Jope, R.S.2
  • 11
    • 79952369773 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production
    • Valerio A, Bertolotti P, Delbarba A, Perego C, Dossena M, Ragni M, et al. Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production. J Neurochem. 2011;116:1148-1159.
    • (2011) J Neurochem. , vol.116 , pp. 1148-1159
    • Valerio, A.1    Bertolotti, P.2    Delbarba, A.3    Perego, C.4    Dossena, M.5    Ragni, M.6
  • 12
    • 0034718421 scopus 로고    scopus 로고
    • Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
    • Bhat RV, Shanley J, Correll MP, Fieles WE, Keith RA, Scott CW, et al. Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration. Proc Natl Acad Sci U S A. 2000;97:11074-11079.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 11074-11079
    • Bhat, R.V.1    Shanley, J.2    Correll, M.P.3    Fieles, W.E.4    Keith, R.A.5    Scott, C.W.6
  • 13
    • 0035900197 scopus 로고    scopus 로고
    • Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium
    • King TD, Bijur GN, Jope RS. Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium. Brain Res. 2001;919:106-114.
    • (2001) Brain Res. , vol.919 , pp. 106-114
    • King, T.D.1    Bijur, G.N.2    Jope, R.S.3
  • 14
    • 33747183699 scopus 로고    scopus 로고
    • Akt/gsk3beta survival signaling is involved in acute brain injury after subarachnoid hemorrhage in rats
    • Endo H, Nito C, Kamada H, Yu F, Chan PH. Akt/gsk3beta survival signaling is involved in acute brain injury after subarachnoid hemorrhage in rats. Stroke. 2006;37:2140-2146.
    • (2006) Stroke , vol.37 , pp. 2140-2146
    • Endo, H.1    Nito, C.2    Kamada, H.3    Yu, F.4    Chan, P.H.5
  • 15
    • 46749109127 scopus 로고    scopus 로고
    • The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole blood
    • Wang J, Fields J, Dore S. The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole blood. Brain Res. 2008;1222:214-221.
    • (2008) Brain Res. , vol.1222 , pp. 214-221
    • Wang, J.1    Fields, J.2    Dore, S.3
  • 16
    • 85028103629 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice
    • Ma Q, Manaenko A, Khatibi NH, Chen W, Zhang JH, Tang J. Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice. J Cereb Blood Flow Metab. 2010;31:881-893.
    • (2010) J Cereb Blood Flow Metab. , vol.31 , pp. 881-893
    • Ma, Q.1    Manaenko, A.2    Khatibi, N.H.3    Chen, W.4    Zhang, J.H.5    Tang, J.6
  • 17
    • 33745808357 scopus 로고    scopus 로고
    • Discovery of n-[(3r)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5- carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: Synthesis and structure-activity relationship
    • Wishka DG, Walker DP, Yates KM, Reitz SC, Jia S, Myers JK, et al. Discovery of n-[(3r)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5- carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure-activity relationship. J Med Chem. 2006;49:4425-4436.
    • (2006) J Med Chem. , vol.49 , pp. 4425-4436
    • Wishka, D.G.1    Walker, D.P.2    Yates, K.M.3    Reitz, S.C.4    Jia, S.5    Myers, J.K.6
  • 18
    • 0028959038 scopus 로고
    • Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats: Statistical validation
    • Garcia JH, Wagner S, Liu KF, Hu XJ. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats: statistical validation. Stroke. 1995;26:627-634.
    • (1995) Stroke , vol.26 , pp. 627-634
    • Garcia, J.H.1    Wagner, S.2    Liu, K.F.3    Hu, X.J.4
  • 19
    • 0036791849 scopus 로고    scopus 로고
    • Behavioral tests after intracerebral hemorrhage in the rat
    • Hua Y, Schallert T, Keep RF, Wu J, Hoff JT, Xi G. Behavioral tests after intracerebral hemorrhage in the rat. Stroke. 2002;33:2478-2484.
    • (2002) Stroke , vol.33 , pp. 2478-2484
    • Hua, Y.1    Schallert, T.2    Keep, R.F.3    Wu, J.4    Hoff, J.T.5    Xi, G.6
  • 21
    • 17644363739 scopus 로고    scopus 로고
    • Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage
    • Ostrowski RP, Colohan AR, Zhang JH. Mechanisms of hyperbaric oxygen-induced neuroprotection in a rat model of subarachnoid hemorrhage. J Cereb Blood Flow Metab. 2005;25:554-571.
    • (2005) J Cereb Blood Flow Metab. , vol.25 , pp. 554-571
    • Ostrowski, R.P.1    Colohan, A.R.2    Zhang, J.H.3
  • 24
    • 33947668266 scopus 로고    scopus 로고
    • T-maze alternation in the rodent
    • Deacon RM, Rawlins JN. T-maze alternation in the rodent. Nat Protoc. 2006;1:7-12.
    • (2006) Nat Protoc. , vol.1 , pp. 7-12
    • Deacon, R.M.1    Rawlins, J.N.2
  • 25
    • 29044441975 scopus 로고    scopus 로고
    • Mechanisms of brain injury after intracerebral haemorrhage
    • Xi G, Keep RF, Hoff JT. Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol. 2006;5:53-63.
    • (2006) Lancet Neurol. , vol.5 , pp. 53-63
    • Xi, G.1    Keep, R.F.2    Hoff, J.T.3
  • 26
    • 0032996631 scopus 로고    scopus 로고
    • Progression of mass effect after intracerebral hemorrhage
    • Zazulia AR, Diringer MN, Derdeyn CP, Powers WJ. Progression of mass effect after intracerebral hemorrhage. Stroke. 1999;30:1167-1173.
    • (1999) Stroke , vol.30 , pp. 1167-1173
    • Zazulia, A.R.1    Diringer, M.N.2    Derdeyn, C.P.3    Powers, W.J.4
  • 27
    • 77954584878 scopus 로고    scopus 로고
    • Alpha7 nicotinic receptor agonists: Potential therapeutic drugs for treatment of cognitive impairments in schizophrenia and Alzheimer's disease
    • Toyohara J, Hashimoto K. Alpha7 nicotinic receptor agonists: potential therapeutic drugs for treatment of cognitive impairments in schizophrenia and Alzheimer's disease. Open Med Chem J. 2010;4:37-56.
    • (2010) Open Med Chem J. , vol.4 , pp. 37-56
    • Toyohara, J.1    Hashimoto, K.2
  • 28
    • 0025160022 scopus 로고
    • Methyllycaconitine: A selective probe for neuronal alpha-bungarotoxin binding sites
    • Ward JM, Cockcroft VB, Lunt GG, Smillie FS, Wonnacott S. Methyllycaconitine: a selective probe for neuronal alpha-bungarotoxin binding sites. FEBS Lett. 1990;270:45-48.
    • (1990) FEBS Lett. , vol.270 , pp. 45-48
    • Ward, J.M.1    Cockcroft, V.B.2    Lunt, G.G.3    Smillie, F.S.4    Wonnacott, S.5
  • 29
    • 34547558959 scopus 로고    scopus 로고
    • The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation
    • de Jonge WJ, Ulloa L. The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation. Br J Pharmacol. 2007;151:915-929.
    • (2007) Br J Pharmacol. , vol.151 , pp. 915-929
    • De Jonge, W.J.1    Ulloa, L.2
  • 30
    • 79952487267 scopus 로고    scopus 로고
    • Application of alpha7 nicotinic acetylcholine receptor agonists in inflammatory diseases: An overview
    • Marrero MB, Bencherif M, Lippiello PM, Lucas R. Application of alpha7 nicotinic acetylcholine receptor agonists in inflammatory diseases: an overview. Pharm Res. 2011;28:413-416.
    • (2011) Pharm Res. , vol.28 , pp. 413-416
    • Marrero, M.B.1    Bencherif, M.2    Lippiello, P.M.3    Lucas, R.4
  • 31
    • 77956545744 scopus 로고    scopus 로고
    • Preclinical and clinical research on inflammation after intracerebral hemorrhage
    • Wang J. Preclinical and clinical research on inflammation after intracerebral hemorrhage. Prog Neurobiol. 2010;92:463-477.
    • (2010) Prog Neurobiol. , vol.92 , pp. 463-477
    • Wang, J.1
  • 32
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science. 2004;303:1483-1487.
    • (2004) Science. , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 33
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H, Bauer A, Stappert J, Kispert A, Kemler R. Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 1997;16:3797-3804.
    • (1997) EMBO J. , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.